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1.
Lymphology ; 52(3): 134-142, 2019.
Article in English | MEDLINE | ID: mdl-31874125

ABSTRACT

The objective of this study was to evaluate the accuracy of bioimpedance spectroscopy measurements (L-Dex) in the diagnosis of breast cancer-related lymphedema. A retrospective review of a prospectively maintained database was performed of all patients that underwent surgical treatment for breast cancer at a tertiary medical center. Patients who had preoperative and postoperative evaluation for possible lymphedema by limb circumference measurements and bioimpedance were eligible for inclusion in the study. No significant demographic differences were found between the group of patients clinically diagnosed with lymphedema (N=134) and those without a clinical diagnosis of lymphedema (N=261). The ability of bioimpedance to diagnose lymphedema based on the manufacturer's criteria demonstrated low sensitivity, which was 7.5% when lymphedema was defined as an absolute L-Dex value greater than 10, and 24.6% when defined as a relative change of >10 between preoperative and postoperative measurements. This corresponded with a positive predictive value of 61-71% and a negative predictive value of 67-70%. We are unable to recommend the use of bioimpedance as a screening tool or for measurement of breast cancer-related lymphedema.


Subject(s)
Breast Cancer Lymphedema/diagnosis , Dielectric Spectroscopy , Electric Impedance , Aged , Arm/pathology , Arm/physiopathology , Breast Cancer Lymphedema/etiology , Breast Neoplasms/complications , Breast Neoplasms/surgery , Dielectric Spectroscopy/methods , Female , Humans , Middle Aged , Retrospective Studies , Severity of Illness Index
2.
Ann Burns Fire Disasters ; 28(1): 39-45, 2015 Mar 31.
Article in English | MEDLINE | ID: mdl-26668561

ABSTRACT

The management of patients suffering from burn injury poses unique challenges for the reconstructive surgeon, both in the acute and delayed settings. Once resuscitative measures are optimized and hemodynamic stability is achieved, early burn debridement and coverage is performed. Traditionally, this consists of excision of devitalized tissue and subsequent coverage using split thickness skin grafts. However, in certain instances, and depending on the extent and nature of the burn injury, skin grafting (or even local tissue rearrangement) may not be a reasonable option. in these cases, free tissue transfer may provide a viable reconstructive alternative. While free flap reconstruction is rare in burn surgery, particularly in the acute setting, burn injuries that expose vital structures, such as tendon, nerve, bone, or deep vessels, require robust flap coverage. in the delayed setting, unsightly scar formation and contracture often occurs secondary to skin graft coverage. These significant patient morbidities are often amenable to free tissue transfer as well. This review article discusses the indications, applications, and problems with free flap surgery for burn injuries in both the acute and delayed setting, and summarizes the available literature on microsurgical free tissue transfer for burn management.


La prise en charge des patients atteints de brûlures pose des défis uniques pour le chirurgien de reconstruction, à la fois dans les cadres aigus et retardés. Une fois les mesures de réanimation sont optimisés et la stabilité hémodynamique est obtenue, il faut faire le débridement précoce et la couverture de la brûlure. Traditionnellement, il s'agit de l'excision des tissus dévitalisés et la couverture par division ultérieure en utilisant des greffes de peau partielle épaisse. Cependant, dans certains cas, et en fonction des dimensions et la nature de la brûlure, une greffe de peau n'est pas toujours une option raisonnable. Dans ces cas, le transfert de tissu libre peut fournir une alternative viable. Alors que la reconstruction de lambeau libre est rare dans la chirurgie des brûlures, en particulier dans le cadre aiguë, les brûlures qui exposent les structures vitales, telles que les tendons, nerfs, os, ou les vaisseaux profonds, nécessitent une couverture robuste. Dans le cadre retardé, la formation de cicatrices inesthétiques et de contractures se produit fréquemment secondaire à une couverture de greffe de peau. Souvent ces morbidités importantes sont aussi prêtent au transfert de tissu libre. Cet article de revue discute les indications, les applications, et des problèmes avec la chirurgie de lambeau libre pour des brûlures dans les cadres aigus et retardés. Cet article résume aussi la littérature disponible sur la microchirurgie du transfert de tissu libre pour la prise en charge des brûlures.

4.
Australas Radiol ; 43(4): 495-9, 1999 Nov.
Article in English | MEDLINE | ID: mdl-10901966

ABSTRACT

Adjuvant radiation therapy to the parotid bed is commonly administered following surgical resection using either a pair of angled wedged photon beams or an ipsilateral mixed-beam portal of electrons and photons. The present study seeks to determine the optimal parotid bed treatment technique in the presence of a titanium mandibular implant by investigating perturbations in the dose distribution deep to this implant for a 15-MeV electron beam and a 6-MV photon beam. A titanium mandibular plate was embedded in a tissue-equivalent phantom, and irradiated with 15-MeV electrons, and 6 MV photons. Radiation doses behind the plate were measured with both thermoluminescent dosimeters and radiographic film. With 15-MeV electrons, there is a clinically significant decrease in the dose beyond the titanium plate, which is most important at 5-mm and 10-mm depths (18-27%). With 6-MV photons the dose at the deep interface of titanium and tissue is reduced by between 15 and 18%, but rapidly drops to < 5% at a depth of 5 mm. In adjuvant treatment to the parotid bed, when the clinical target volume includes tissue positioned deep to a titanium implant, significant underdosage occurs with ipsilateral beam arrangements, especially when electrons are used.


Subject(s)
Mandible/surgery , Parotid Gland/radiation effects , Prostheses and Implants , Radiotherapy, High-Energy , Titanium , Electrons , Phantoms, Imaging , Photons , Radiotherapy Dosage
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