1.
Bull Exp Biol Med
; 150(4): 436-9, 2011 Feb.
Article
in English
| MEDLINE
| ID: mdl-22268037
ABSTRACT
We demonstrated an increase in glutamate neurocytotoxicity in cultured cerebellar cells from rat pups subjected to lead poisoning during the prenatal development or early lactation period. The toxic effect of glutamate was weaker, if lead was applied in combination with antioxidant comenic acid. These data are discussed in view of practical use of comenic acid for the therapy of the brain tissues subjected to lead poisoning.
Subject(s)
Carboxylic Acids/pharmacology , Glutamates/toxicity , Lead Poisoning, Nervous System/drug therapy , Neurons/drug effects , Neuroprotective Agents/pharmacology , Pyrones/pharmacology , Animals , Animals, Newborn , Brain/drug effects , Brain/metabolism , Brain/pathology , Cells, Cultured , Female , Neurons/metabolism , Neurons/pathology , Pregnancy , Rats , Rats, Wistar
2.
Bull Exp Biol Med
; 138(3): 262-3, 2004 Sep.
Article
in English
| MEDLINE
| ID: mdl-15665919
ABSTRACT
Addition of green tea extract in concentrations of 0.004-0.006% to the nutrient medium markedly stimulated the growth of spinal ganglion neurites of 1-2-day-old rats.
