[Effect of hyperprolactinemia of varying origin on paracrine relationships in rat testes]. / Vliianie giperprolaktinemii razlichnogo geneza na parakrinnye vzaimootnosheniia v semennikakh krys.

Light microscopy characteristics of mature rat testes were studied in control and hyperprolactinemia rats. The number of cells defined as granulocytes in interstitial regions adjacent to seminal ducts at stage VII and XII of spermatogenesis has been calculated. Normal deference difference between these parameters diminish in hyperprolactinemia. It is suggested that prolactin participates in intratesticular paracrine mechanisms regulation.

[Monocyte-macrophage infiltration in portions of atherosclerotic lesions of the human aorta]. / Monotsitarno-makrofagal'naia infil'tratsiia v uchastkakh rannikh ateroskleroticheskikh porazhenii aorty cheloveka.

Human thoracic aorta was taken from trauma victims aged from 6 to 40 years. Cell composition of the intimal layer was investigated in the lesion predisposed (LP) areas of the aorta and in the lesion resistant (LR) areas. By double immunofluorescent staining with mono and polyclonal antibodies to monocytes/macrophages (Mn/Mph) and smooth muscle cells (SMC) the presence of Mn/Mph was revealed in all aortas studied. The number of these cells was 2-6 fold higher in LP areas, compared to LR areas in all persons over 21 years of age. Scanning electron microscopy revealed Mn on the luminal surface of the vessel the number of which was frequently higher in LP areas. Mn/Mph in LP areas were heterogeneous in their structure depending on the depth of their localization in the intima. The revealed Mn/Mph infiltration in aortas of young subjects may be the earliest manifestation of the atherosclerotic lesion.