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Chem Biodivers ; 12(11): 1678-95, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26567946

ABSTRACT

The content of biogenic compounds and the biological activities of barley (Hordeum vulgare L.)-grain extracts was evaluated. The sufficiently large and heterogeneous set of barley genotypes (100 accessions) enabled the selection of special genotypes interesting for potential industrial, pharmaceutical, and medicinal applications. Barley genotypes with the highest contents of phenols, phenolic acids, flavonoids, biogenic thiols, and amines, radical-scavenging activity, as well as inhibitory activities of trypsin, thrombin, collagenase, urokinase, and cyclooxygenase were identified.


Subject(s)
Antioxidants/pharmacology , Enzyme Inhibitors/pharmacology , Hordeum/chemistry , Plant Extracts/chemistry , Antioxidants/chemistry , Antioxidants/isolation & purification , Collagenases/metabolism , Enzyme Inhibitors/chemistry , Enzyme Inhibitors/isolation & purification , Genotype , Hordeum/genetics , Humans , Prostaglandin-Endoperoxide Synthases/metabolism , Structure-Activity Relationship , Thrombin/antagonists & inhibitors , Thrombin/metabolism , Trypsin/metabolism , Urokinase-Type Plasminogen Activator/antagonists & inhibitors , Urokinase-Type Plasminogen Activator/metabolism
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