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Joint Bone Spine ; 76(5): 565-6, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19767229

ABSTRACT

Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal Langerhans cell histiocytosis of bone and skin, revealed by a pain of the left hip and a limp trailing from 2 months. The diagnosis has been established by histological exam. The patient received chemotherapy and steroids. Outcome was favourable over 6-month follow-up. Trailing limp should evoke diagnosis of Langerhans cell histiocytosis. Skin biopsy should be preferred to a bone biopsy because of its safety.


Subject(s)
Hip Joint/pathology , Histiocytosis, Langerhans-Cell/pathology , Adrenal Cortex Hormones/therapeutic use , Female , Femur/diagnostic imaging , Femur/pathology , Functional Laterality , Hip Joint/diagnostic imaging , Histiocytosis, Langerhans-Cell/diagnostic imaging , Histiocytosis, Langerhans-Cell/drug therapy , Humans , Infant , Magnetic Resonance Imaging , Osteosclerosis/diagnostic imaging , Otitis/diagnosis , Pain/etiology , Radiography , Treatment Outcome
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