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Bioorg Med Chem Lett
; 21(10): 3117-21, 2011 May 15.
Article
in English
| MEDLINE
| ID: mdl-21458262
ABSTRACT
A series of 6-azanaphthoquinone pyrrolo-annelated derivatives carrying different basic side chains have been synthesized. The antiproliferative activities of all compounds were evaluated on at least four different cell lines with Mitoxantrone as reference compound. Cytotoxic effects and DNA intercalation behavior were investigated.