[The characteristics of the course of the acute and recovery periods in myocardial infarct in patients who resided in the neighborhood of the Chernobyl Atomic Electric Power Station]. / Osobennosti techeniia ostrogo i vosstanovitel'nogo periodov infarkta miokarda u bol'nykh, nakhodivshikhsia na territorii, priblizhennoi k ChAES.

Results are submitted of a 6-month follow-up of 30 patients with prior myocardial infarction residing in the neighbourhood of the Chernobyl Nuclear Power Plant, involving investigations designed to study hemodynamics together with immunologic reactivity. A comparison group was formed of 25 Kievites. Both groups demonstrated alterations of immunologic respectively. A conclusion has been reached that there exists association between the above findings and development of myocardial infarction but no relationship was found with exposure to radiation.

[Ventricular fibrillation in myocardial infarct patients: the factors determining the prognosis]. / Fibrilliatsiia zheludochka u bol'nykh infarktom miokarda: faktory, opredeliaiushchee prognoz.

Improvement of methods for diagnosis and treatment of myocardial infarction and its complications permitted the mortality and disability resulting from this condition to be considerably reduced. The aim of the study was to analyse in retrospect clinical and functional disorders in subjects with a history of ventricular fibrillation in the acute phase. Over 3 years, 1096 patients with acute myocardial infarction had been admitted to the Department of Cardioresuscitation. Ventricular Fibrillation was cause of death in 2.1% of cases. Over this time period, resuscitation was a success in 2.9%. The following item was found out to be a factor of unfavourable prognosis during the first two years after development of acute myocardial infarction: it was postinfarction dilatation of the left ventricle having a part in the evolution of cardiac insufficiency and contributing to formation of arrhythmogenic substrate and, to a lesser degree, to ventricular fibrillation in the acute phase.

[The characteristics of the rehabilitative treatment of patients with a history of unstable stenocardia]. / Osobennosti vosstanovitel'nogo lecheniia bol'nykh, perenesshikh nestabil'nuiu stenokardiiu.

While examining forty-nine patients with the history of unstable angina pectoris (UAP), it was established that the sanatorium stage of rehabilitation with the proper extension of sick leave being accorded to such patients, is indicated in cases of low tolerability of physical exercise (50 wt and less) when discharged from hospital. Those patients with prior UAP who can tolerate physical exercise at 75 wt and above, are recommended to resume their work. In addition, improvement in tolerability of physical work loads in patients with prior UAP was found to be accompanied by diminution in the left ventricle cavity size.

[The use of the preparation Lomir in patients with arterial hypertension and postinfarct cardiosclerosis]. / Primenenie preparata "Lomir" u bol'nykh s arterial'noi gipertenziei ipostinfarktnym kardiosklerozom.

As many as 26 patients with arterial hypertension (AH) associated with postmyocardial infarction cardiosclerosis were examined for assessing the efficacy of a new preparation belonging to a panel of calcium antagonists, viz. isradipine (<> by SANDOZ). Of note, a positive result was observed in 88%, which fact was manifested by normalization of AH without any side effects. Half the patient population showed improved tolerability of physical loads by lowering AH increments and reduction in the myocardium oxygen demand. Thus, use of <> in a combined treatment of patients surviving myocardial infarction and suffering from AH, furthers reconvalescence and improves tolerability of physical loads.

[The results of the rehabilitative treatment of patients who have had a myocardial infarct complicated by a block of the right branch of the atrioventricular bundle]. / Rezul'taty vosstanovitel'nogo lecheniia bol'nykh, perenesshikh infarkt miokarda, oslozhnennyi blokadoi pravoi nozhki predserdno-zheludochkovogo puchka.

The disturbances in the cardiac left ventricular contractility have been shown to be much graver in complete blockade of the right bundle of His as evidenced by the examination of 35 patients who had a history of myocardial infarction, and data from the two-year follow-up. The data obtained should be considered in determining time for the patients fo return to their ordinary activities and become functional members of society.

[The rehabilitative treatment of patients after a myocardial infarct who reside in an area close to the Chernobyl Atomic Electric Power Station]. / Vosstanovitel'noe lechenie bol'nykh posle infarkta miokarda, nakhodivshikhsia v zone, priblizhennoi k Chernobyl'skoi AES.

Rehabilitation treatment is evaluated in 55 patients (long-term results) with a history of myocardial infarction residing in the Chernobyl atomic station zone. It was established that the course of the disease in persons who participated in liquidation of the Chernobyl disaster was characterized by a more frequent development of reinfarctions as compared with the Kiev population. Patients residing in the zone neighbouring the Chernobyl station developed more frequently cardiac failure. This requires detailed examination of these patients during their return to work.

[A program for the accelerated activation of myocardial infarct patients and its implementation in the hospitals and sanatoria of Ukraine]. / Programma uskorennoi aktivatsii bol'nykh infarktom miokarda i ee realizatsiia v statsionarakh i sanatoriiakh Ukrainy.

The possibility is shown of reducing the time of hospitalization for 7-12 days in 25% of patients with a history of myocardial infarction. An analysis of health resort rehabilitation of patients according to program of enhanced activation revealed that such rehabilitation program proved effective and showed the possibility of its realization in conditions of practical medicine.

[The age-related characteristics of the cardiodynamics of patients who have had a myocardial infarct]. / Vozrastnye osobennosti kardiodinamiki u bol'nykh, perenesshikh infarkt miokarda.

Age-related effects on the function of restoration in 254 patients with a history of myocardial infarction were investigated. It was found that the age effect influenced tolerance to physical load, the values of which are not always related to the character of the sustained infarction of the myocardium.

[Predicting the efficacy of rehabilitation in patients with prior myocardial infarction]. / Prognozirovanie éffektivnosti vosstanovitel'nogo lecheniia u bol'knykhperenesshikh infarkt miokarda.

The results of a 2-year follow-up of 400 patients with prior myocardial infarction (MI) and bicycle ergometric findings of intracardiac hemodynamic parameters and oxygen supply during exercise tests, and the criteria for tetrachoric index significance within the confidence intervals were used to reveal the factors predicting the efficacy of rehabilitative treatment. To predict decreased working capacity in the long-term period is determined by the extent of lesion after myocardial reinfarction, while angina pectoris and arterial hypertension are of significance in patients without reinfarction. A role of dynamic indices was defined in predicting decreased working capacity. Further lowered working capacity may be judged from the changes occurring in threshold exercise capacity and left ventricular end-diastolic volume in the first 6 months of postinfarction.

[Enterosorbent SKN in the combined rehabilitative treatment of patients who have had a myocardial infarct]. / Enterosorbent SKN v kompleksnom vosstanovitel'nom lechenii bol'nykh, perenesshikh infarkt miokarda.

A study of 34 patients with 2-3 months history of myocardial infarction revealed that 10-day course of treatment with SKN enterosorbent resulted in normalization of lipid peroxidation and several indices of lipid metabolism. These changes were in a part of the patients accompanied by an increase of tolerance to physical load and reduced requirement of the myocardium in oxygen.

[Modeling the effectiveness of the rehabilitation treatment of patients in the post-infarction period]. / Modelirovanie éffektivnosti vosstanovitel'nogo lecheniia bol'nykh, perenesshikh infarkt miokarda.

A two-year follow-up of 400 patients with prior myocardial infarction and usage of regression and discriminant analysis algorithms provided a number of linear models to predict changes in the patients' working capacity over the observed period. A variety of models depending on the feasibility of a laboratory to apply instrumental tools for examination suggested their wide utilization. The advantage of the models is that a small set of signs is used, no computer engineering is required. The models may be used in patients with different clinical disease (uncomplicated, repeated or cardiac aneurysm-complicated myocardial infarction). The modelling provided accurate prediction at 84-100% levels.

[Diastolic function of the left heart ventricle in patients after myocardial infarct]. / Diastolicheskaia funktsiia levogo zheludochka serdtsa u bol'nykh, perenesshikh infarkt miokarda.

Altogether 129 patients were investigated 3 months after the onset of myocardial infarction (MI). Left ventricular diastolic function was assessed using a set of parameters of radionuclide ventriculography, including fractions of filling of the first and second thirds of the diastole, increments of volumes in the phases of fast and slow filling, a maximum rate of filling and the time of achieving it. Marked disorders of isovolumetric relaxation (indices of filling of the first third of the diastole) as well as changes of volumetric compliance (a ratio of increments of volumes of filling of the first and second thirds of the diastole) were revealed in the patients. A degree of disorder of left ventricular diastolic function and MI localization showed no correlation, however more noticeable changes were observed in the group of patients with the anterio-apical localization of myocardial lesion as compared to patients with lesions of posterior-lateral localization.