[Androgenic function of the adrenal cortex in girl athletes with retarded sexual development]. / Androgennaia funktsiia kory nadpochechnikov u devochek-sportsmenok s zaderzhkoi polovogo razvitiia.

Diurnal excretion of 17-ketosteroids and their fractions was studied in 43 girl athletes with retarded sexual development (RSD) and 22 patients who did not go in for sports. Twenty-five healthy girls with a normal menstrual cycle constituted the control group. Athletes with RSD showed relative hyperandrogeny marked by a higher proportion of more active androgenic fractions (dehydroepiandrosterone and androsterone) in total 17-ketosteroids. Excretion of neutral 17-ketosteroids in athletes examined, as compared with non-athletes with RSD, was within age-associated norms or surpassed them. It is suggested that androgens of the adrenal cortex are involved into the pathogenesis of RSD in female athletes.

[Gonadotropic function of the pituitary gland and the antigonadotropin activity in healthy girls]. / Gonadotropnaia funktsiia gipofiza i aktivnost' antigonadotropinov u zdorovykh devochek.

This clinical and laboratory investigation is devoted to the study of the levels and correlation between the total gonadotropins and antigonadotropin factors excreted in the urine of 10-18-year-old girls. There was found a correlation between the excretion of total gonadotropins and the concentration of their inhibitors. Periods of the greatest fall of the antigonadotropin level corresponded to the peaks of gonadotropin activity.