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1.
Prev Sci ; 24(6): 1078-1090, 2023 08.
Article in English | MEDLINE | ID: mdl-37052866

ABSTRACT

Major research breakthroughs over the past 30 years in the field of substance use prevention have served to: (1) enhance understanding of pharmacological effects on the central and peripheral nervous systems and the health and social consequences of use of psychoactive substances, particularly for children and adolescents; (2) delineate the processes that increase vulnerability to or protect from initiation of substance use and progression to substance use disorders (SUDs) and, based on this understanding, (3) develop effective strategies and practices to prevent the initiation and escalation of substance use. The challenge we now face as a field is to "normalize" what we have learned from this research so that it is incorporated into the work of those involved in supporting, planning, and delivering prevention programming to populations around the world, is integrated into health and social service systems, and helps to shape public policies. But we wish to go further, to incorporate these effective prevention practices into everyday life and the mind-sets of the public, particularly parents and educators. This paper reviews the advances that have been made in the field of prevention and presents a framework and recommendations to achieve these objectives generated during several meetings of prevention and implementation science researchers sponsored by the International Consortium of Universities for Drug Demand Reduction (ICUDDR) that guides a roadmap to achieve "normalization."


Subject(s)
Substance-Related Disorders , Adolescent , Child , Humans , Substance-Related Disorders/prevention & control , Cognition , Implementation Science , Learning , Parents
2.
Clin Child Fam Psychol Rev ; 26(1): 1-16, 2023 03.
Article in English | MEDLINE | ID: mdl-36542196

ABSTRACT

The recently released National Drug Control Strategy (2022) from the White House Office of National Drug Control Policy (ONDCP) lays out a comprehensive plan to, not only enhance access to treatment and increase harm reduction strategies, but also increase implementation of evidence-based prevention programming at the community level. Furthermore, the Strategy provides a framework for enhancing our national data systems to inform policy and to evaluate all components of the plan. However, not only are there several missing components to the Strategy that would assure its success, but there is a lack of structure to support a national comprehensive service delivery system that is informed by epidemiological data, and trains and credentials those delivering evidence-based prevention, treatment, and harm reduction/public health interventions within community settings. This paper provides recommendations for the establishment of such a structure with an emphasis on prevention. Systematically addressing conditions known to increase liability for behavioral problems among vulnerable populations and building supportive environments are strategies consistently found to avert trajectories away from substance use in general and substance use disorders (SUD) in particular. Investments in this approach are expected to result in significantly lower rates of SUD in current and subsequent generations of youth and, therefore, will reduce the burden on our communities in terms of lowered social and health systems involvement, treatment needs, and productivity. A national strategy, based on strong scientific evidence, is presented to implement public health policies and prevention services. These strategies work by improving child development, supporting families, enhancing school experiences, and cultivating positive environmental conditions.


Subject(s)
Opioid-Related Disorders , Child , Humans , Adolescent , Opioid-Related Disorders/epidemiology , Opioid-Related Disorders/prevention & control
3.
J Drug Educ ; 51(3-4): 82-100, 2022 09.
Article in English | MEDLINE | ID: mdl-37365824

ABSTRACT

This group-randomized trial assessed the effects of a universal prevention training curriculum for school administrators and teachers that focused on effective strategies to prevent adolescent substance use and related problems. Twenty-eight schools in three regions of Peru were randomly assigned to either an intervention or control condition (14 schools per condition). Repeated cross-sectional samples of 11 to 19-year-old students participated in four surveys from May 2018 to November 2019 (N = 24,529). School administrators and teachers at intervention schools participated in a universal prevention training curriculum focusing on the development of a positive school climate as well as effective policies related to school substance use. All intervention and control schools were offered Unplugged, a classroom-based substance use prevention curriculum. Outcome measures included: lifetime drug use; past-year and past-month tobacco, alcohol, marijuana, and other drug use; awareness of school tobacco and alcohol use policies; perceived enforcement of school policies; school bonding; perceived friends' use of tobacco, alcohol, marijuana and other drugs; and personal problems in general and problems related to substance use. Multi-level analyses indicated significant reductions in past-year and past-month smoking, friends' substance use, and problems related to substance use and in general at intervention relative to control schools. Significant increases were found in intervention vs. control schools related to students' awareness of school substance use policies, perceived likelihood of getting caught for smoking, and school bonding. These findings suggest that the universal prevention training curriculum and the school policy and climate changes it promoted reduced substance use and related problems in the study population of Peruvian adolescents.


Subject(s)
Schools , Substance-Related Disorders , Humans , Adolescent , Child , Young Adult , Adult , Peru , Cross-Sectional Studies , Curriculum , Substance-Related Disorders/prevention & control , Substance-Related Disorders/epidemiology
4.
Prev Sci ; 22(1): 84-90, 2021 01.
Article in English | MEDLINE | ID: mdl-32886318

ABSTRACT

Despite significant progress in prevention science over the past 30 years in developing evidence-based interventions and policies, there has not been equal success in attracting support from policymakers and gaining acceptance by communities. In recognition of this gap, the editors of Prevention Science put out a call to scientists to help clarify and define the concept of a "culture of prevention." Such a culture would influence the creation of an infrastructure for implementing and sustaining the most effective strategies informed by research. The journal call stated a culture of prevention was a "general orientation or readiness of a group of people… to address problems by using a preventive, rather than a reactive approach." This commentary examines the concept demonstrated in the array of papers presented here in which the "culture of prevention" is applied in different contexts-occupational safety and health, substance use, school, governmental, community, around problem behaviors, and violence. It is important to note that the papers represent perspectives and experiences from several countries, including some cross-national experiences providing an international framework. While a final definition awaits further research, the commentary summarizes important elements that might constitute that evolving definition and pave the way for the implementation of more effective prevention programming.


Subject(s)
Substance-Related Disorders , Violence/prevention & control , Humans , Occupational Health , Substance-Related Disorders/prevention & control
6.
Cent Eur J Public Health ; 27 Suppl: S74-S82, 2019 12.
Article in English | MEDLINE | ID: mdl-31901195

ABSTRACT

OBJECTIVE: Comprehensive bachelor's, master's, and doctorate-level curricula of Addiction Studies (Addictology) were developed and implemented at Charles University (First Faculty of Medicine) between 2003 and 2012. This Prague model combines three evidence-based approaches to addressing substance use - prevention, treatment, and public health - into a balanced professionalised discipline. Graduates from this programme are licensed by the State Authority as addictology, a regulated profession in the Czech Republic. Professionals with these degrees are recognised as healthcare professionals, can perform directly in the field and can be contracted by health insurance companies. In 2016, it was decided to integrate the Universal Prevention Curriculum (UPC) into these programmes of study. The UPC was developed by a group of prevention researchers from the United States. This article describes the technical steps involved when adapting the UPC into an established university degree programme. We describe the requirements needed for successful implementation and reaccreditation. Finally, we examine both barriers and enhancers of the adoption of UPC as a university programme. METHODS: A qualitative process evaluation study was conducted on the activities carried out in 2017-2018, demarcated by a successful university accreditation of the new curricula combining the original Prague model and the UPC curriculum. Field records, observation methods, official documents, curricular documents, syllabuses, content analysis, and thematic analysis were used for this process. RESULTS: We identified three clusters of issues and challenges during the adaptation and implementation process: technical (developing a new credit scheme, adopting new terminology using local and culture-specific examples, and cancelling, establishing, and/or fusing particular courses, identifying some critical issues for any practical implementation of the UPC); teaching staff-related (team work, involving motivated and qualified staff for moving from a national to an international perspective); and content and contextual (the conflict between different theoretical perspectives such as public health vs. mental health and drug use prevention vs. risk behaviour prevention). CONCLUSION: The adaptation of the UPC had a significant impact on study profiles and competencies. Such an implementation necessarily requires a team of staff members with sufficient capacities to be able to coordinate the process, facilitating each step and supervising it. The current adaptation of the UPC involved specific merging procedures to fit in with existing courses and emphasising an international perspective. This process opened a national discussion about the implementation of the UPC in the system of life-long education programmes and training. Beginning in September 2019, when the first group of students will attend this new model of Addictology studies, we will continue our evaluation of the implementation process and the factors that played a role in either hindering or supporting the implementation. The findings from this evaluation will be used to make adjustments to the curriculum.


Subject(s)
Addiction Medicine/education , Curriculum , Education, Medical, Graduate/organization & administration , Education, Medical, Undergraduate/organization & administration , Czech Republic , Humans , Program Evaluation , Qualitative Research
7.
Prev Sci ; 17(6): 765-78, 2016 08.
Article in English | MEDLINE | ID: mdl-27220838

ABSTRACT

Internet-connected devices are changing the way people live, work, and relate to one another. For prevention scientists, technological advances create opportunities to promote the welfare of human subjects and society. The challenge is to obtain the benefits while minimizing risks. In this article, we use the guiding principles for ethical human subjects research and proposed changes to the Common Rule regulations, as a basis for discussing selected opportunities and challenges that new technologies present for prevention science. The benefits of conducting research with new populations, and at new levels of integration into participants' daily lives, are presented along with five challenges along with technological and other solutions to strengthen the protections that we provide: (1) achieving adequate informed consent with procedures that are acceptable to participants in a digital age; (2) balancing opportunities for rapid development and broad reach, with gaining adequate understanding of population needs; (3) integrating data collection and intervention into participants' lives while minimizing intrusiveness and fatigue; (4) setting appropriate expectations for responding to safety and suicide concerns; and (5) safeguarding newly available streams of sensitive data. Our goal is to promote collaboration between prevention scientists, institutional review boards, and community members to safely and ethically harness advancing technologies to strengthen impact of prevention science.


Subject(s)
Human Experimentation/ethics , Preventive Medicine , Safety , Technology , Guidelines as Topic , Health Policy , Human Experimentation/legislation & jurisprudence , Humans , Internet
9.
Adicciones ; 26(1): 3-9, 2014.
Article in English | MEDLINE | ID: mdl-24652393

ABSTRACT

The field of drug use prevention has been advanced through a convergence of theories of human behavior, a more enhanced understanding of the factors that have been found to be associated with the onset of drug use, and more sophisticated research methodologies impacting not only study design and measurement but also data analysis. For these reasons, there is a need for a reconceptualization of the intent and function of prevention in order to refine intervention development and implementation. This review will focus primarily on drug use prevention but the implications are clear for other prevention outcome behaviors. The concepts included in this paper are stimulated by recent advances in understanding neurobiological development and revised understanding of the interaction between individual vulnerability and environmental influences. It also draws on the concept of socialization and the role of socialization and socializing agents in any society.


Subject(s)
Substance-Related Disorders/prevention & control , Decision Making , Humans , Socialization , Substance-Related Disorders/psychology
10.
Adicciones (Palma de Mallorca) ; 26(1): 3-9, 2014. ilus, graf
Article in English | IBECS | ID: ibc-119035

ABSTRACT

The field of drug use prevention has been advanced through a convergence of theories of human behavior, a more enhanced understanding of the factors that have been found to be associated with the onset of drug use, and more sophisticated research methodologies impacting not only study design and measurement but also data analysis. For these reasons, there is a need for a reconceptualization of the intent and function of prevention in order to refine intervention development and implementation. This review will focus primarily on drug use prevention but the implications are clear for other prevention outcome behaviors. The concepts included in this paper are stimulated by recent advances in understanding neurobiological development and revised understanding of the interaction between individual vulnerability and environmental influences. It also draws on the concept of socialization and the role of socialization and socializing agents in any society


En el campo de la prevención del consumo de drogas se ha avanzado mediante la convergencia de las teorías del comportamiento humano, una mejor comprensión de los factores asociados con el inicio de dicho consumo, y unas metodologías de investigación más sofisticadas que no afectan sólo al diseño del estudio y la medición, sino también al análisis de datos. Por todas estas razones, se precisa de una reconceptualización de la intención y la función de la prevención con el fin de perfeccionar el desarrollo de la intervención y de la aplicación. Esta revisión se centra principalmente en la prevención del consumo de drogas, pero sus implicaciones son claras para otros comportamientos de resultado de la prevención. Los conceptos incluidos en este artículo se ven estimulados por los avances recientes en la comprensión del desarrollo neurobiológico y se han revisado tomando en consideración la interacción entre vulnerabilidad individual e influencias ambientales. También se recurre al concepto de socialización y al papel de la socialización y de los agentes socializadores en cualquier sociedad


Subject(s)
Humans , Substance-Related Disorders/prevention & control , Vulnerable Populations , Evaluation of Results of Preventive Actions/trends , Decision Support Techniques
11.
Prev Sci ; 14(4): 319-51, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23430579

ABSTRACT

Evidence-based preventive interventions developed over the past two decades represent great potential for enhancing public health and well-being. Research confirming the limited extent to which these interventions have been broadly and effectively implemented, however, indicates much progress is needed to achieve population-level impact. In part, progress requires Type 2 translation research that investigates the complex processes and systems through which evidence-based interventions are adopted, implemented, and sustained on a large scale, with a strong orientation toward devising empirically-driven strategies for increasing their population impact. In this article, we address two core challenges to the advancement of T2 translation research: (1) building infrastructure and capacity to support systems-oriented scaling up of evidence-based interventions, with well-integrated practice-oriented T2 research, and (2) developing an agenda and improving research methods for advancing T2 translation science. We also summarize a heuristic "Translation Science to Population Impact (TSci Impact) Framework." It articulates key considerations in addressing the core challenges, with three components that represent: (1) four phases of translation functions to be investigated (pre-adoption, adoption, implementation, and sustainability); (2) the multiple contexts in which translation occurs, ranging from community to national levels; and (3) necessary practice and research infrastructure supports. Discussion of the framework addresses the critical roles of practitioner-scientist partnerships and networks, governmental agencies and policies at all levels, plus financing partnerships and structures, all required for both infrastructure development and advances in the science. The article concludes with two sets of recommended action steps that could provide impetus for advancing the next generation of T2 translation science and, in turn, potentially enhance the health and well-being of subsequent generations of youth and families.


Subject(s)
Evidence-Based Practice , Translational Research, Biomedical
12.
Prev Sci ; 14(2): 144-56, 2013 Apr.
Article in English | MEDLINE | ID: mdl-21360061

ABSTRACT

This paper presents new methods for synthesizing results from subgroup and moderation analyses across different randomized trials. We demonstrate that such a synthesis generally results in additional power to detect significant moderation findings above what one would find in a single trial. Three general methods for conducting synthesis analyses are discussed, with two methods, integrative data analysis and parallel analyses, sharing a large advantage over traditional methods available in meta-analysis. We present a broad class of analytic models to examine moderation effects across trials that can be used to assess their overall effect and explain sources of heterogeneity, and present ways to disentangle differences across trials due to individual differences, contextual level differences, intervention, and trial design.


Subject(s)
Observer Variation , Randomized Controlled Trials as Topic
14.
Subst Use Misuse ; 47(13-14): 1557-68, 2012.
Article in English | MEDLINE | ID: mdl-23186473

ABSTRACT

This article describes the challenge of sustaining a balanced agenda for drug use research in the USA to advance understanding of the nature and extent of drug use and drug use disorders in a population; the processes and mechanisms that underlie onset, continuing, and stopping drug dependence; how to effectively prevent the onset of and early drug use as well as the social and health consequences of such use; and how to treat and maintain those with drug use disorders. This review concludes with recommendations to achieve sustained stability of funding for and to promote the progress of epidemiologic, prevention, and treatment policy research.


Subject(s)
Health Planning Guidelines , National Institutes of Health (U.S.)/economics , Research Support as Topic/economics , Research Support as Topic/trends , Substance-Related Disorders/economics , Humans , National Institutes of Health (U.S.)/organization & administration , Research Support as Topic/methods , Research Support as Topic/standards , Substance-Related Disorders/epidemiology , Substance-Related Disorders/prevention & control , Substance-Related Disorders/therapy , United States/epidemiology
16.
Subst Use Misuse ; 47(8-9): 944-62, 2012.
Article in English | MEDLINE | ID: mdl-22676565

ABSTRACT

Over the past 20 years we have accumulated a greater knowledge and understanding of the genetic, neurobiological, and behavioral factors that may be associated with young people initiating the use of drugs and other substances and to progressing from use to abuse and dependence. This knowledge suggests that individuals may be "predisposed" to substance use disorders (SUD) and that the actual engagement in these behaviors depends on their environmental experiences from micro to macro levels. This paper summarizes this knowledge base and supports a developmental framework that examines the interaction of posited genetic, psychological, and neurobiological "predispositions" to SUD and those environmental influences that exacerbate this vulnerability.


Subject(s)
Risk Reduction Behavior , Substance-Related Disorders/etiology , Substance-Related Disorders/prevention & control , Adolescent , Child , Child Development , Child, Preschool , Female , Genetic Predisposition to Disease/etiology , Humans , Infant , Male , Pregnancy , Prenatal Exposure Delayed Effects , Psychopathology , Social Environment , Substance-Related Disorders/genetics , Substance-Related Disorders/psychology
17.
Drug Alcohol Depend ; 102(1-3): 1-10, 2009 Jun 01.
Article in English | MEDLINE | ID: mdl-19332365

ABSTRACT

OBJECTIVES: The purpose of the study was to determine whether a universal school-based substance abuse prevention program, Take Charge of Your Life (TCYL), prevents or reduces the use of tobacco, alcohol, or marijuana. METHODS: Eighty-three school clusters (representing school districts) from six metropolitan areas were randomized to treatment (41) or control (42) conditions. Using active consenting procedures, 19,529 seventh graders were enrolled in the 5-year study. Self-administered surveys were completed by the students annually. Trained Drug Abuse Resistance Education (D.A.R.E.) police officers presented TCYL in seventh and ninth grades in treatment schools. Analyses were conducted with data from 17,320 students who completed a baseline survey. Intervention outcomes were measured using self-reported past-month and past-year use of tobacco, alcohol, and marijuana when students were in the 11th grade. RESULTS: Main effect analyses show a negative program effect for use of alcohol and cigarettes and no effect for marijuana use. Subgroup analyses indicated that the negative effect occurred among nonusers at baseline, and mostly among white students of both genders. A positive program effect was found for students who used marijuana at baseline. Two complementary papers explore the relationship of the targeted program mediators to the use of alcohol, tobacco, and marijuana and specifically for students who were substance-free or who used substances at baseline. CONCLUSIONS: The negative impact of the program on baseline nonusers of alcohol and tobacco indicate that TCYL should not be delivered as a universal prevention intervention. The finding of a beneficial effect for baseline marijuana users further supports this conclusion. The programmatic and methodological challenges faced by the Adolescent Substance Abuse Prevention Study (ASAPS) and lessons learned offer insights for prevention researchers who will be designing similar randomized field trials in the future.


Subject(s)
Adolescent , Health Education , Substance-Related Disorders/prevention & control , Alcohol Drinking/epidemiology , Black People , Data Interpretation, Statistical , Ethnicity , Female , Humans , Longitudinal Studies , Marijuana Smoking/epidemiology , Risk , Schools , Sex Factors , Smoking/epidemiology , Students , Substance-Related Disorders/epidemiology , Treatment Outcome , White People
18.
Drug Alcohol Depend ; 102(1-3): 19-29, 2009 Jun 01.
Article in English | MEDLINE | ID: mdl-19362433

ABSTRACT

OBJECTIVE: We examined the relationships among targeted constructs of social influences and competence enhancement prevention curricula and cigarette, alcohol and marijuana use outcomes in a diverse sample of high school students. We tested the causal relationships of normative beliefs, perceptions of harm, attitudes toward use of these substances and refusal, communication, and decision-making skills predicting the self-reported use of each substance. In addition, we modeled the meditation of these constructs through the intentions to use each substance and tested the moderating effects of the skills variables on the relationships between intentions to use and self-reported use of each of these substances. METHODS: Logistic regression path models were constructed for each of the drug use outcomes. Models were run using the Mplus 5.0 statistical application using the complex sample function to control for the sampling design of students nested within schools; full information maximum likelihood estimates (FIML) were utilized to address missing data. RESULTS: Relationships among targeted constructs and outcomes differed for each of the drugs with communication skills having a potentially iatrogenic effect on alcohol use. Program targets were mediated through the intentions to use these substances. Finally, we found evidence of a moderating effect of decision-making skills on perceptions of harm and attitudes toward use, depending upon the outcome. CONCLUSIONS: Prevention curricula may need to target specific drugs. In addition to normative beliefs, perceptions of harm, and refusal and decision-making skills, programs should directly target constructs proximal to behavioral outcomes such as attitudes and intentions. Finally, more research on the effects of communication skills on adolescent substance use should be examined.


Subject(s)
Alcohol Drinking/prevention & control , Health Education , Marijuana Smoking/prevention & control , Smoking Prevention , Substance-Related Disorders/prevention & control , Adolescent , Communication , Data Interpretation, Statistical , Decision Making , Female , Humans , Logistic Models , Male , Models, Statistical , Peer Group , Social Behavior , Surveys and Questionnaires , Treatment Outcome
19.
Drug Alcohol Depend ; 102(1-3): 11-8, 2009 Jun 01.
Article in English | MEDLINE | ID: mdl-19345519

ABSTRACT

OBJECTIVES: In their work examining the effects of the Take Charge of Your Life (TCYL) program, Sloboda and colleagues (This Issue) found that the TCYL program had significant positive effects on baseline marijuana users and significant negative effects on baseline nonusers of cigarettes and alcohol. METHODS: Mediational analyses were used to understand why the program had these differential impacts on baseline users and nonusers. RESULTS: Path models for binary outcomes revealed significant program impacts on marijuana normative beliefs and refusal skills. The treatment impacts were between 1.5 and 3 times larger for the baseline users than for nonusers. These direct effects of the program on normative beliefs and refusal skills mediated the treatment impact on use for baseline marijuana users. In contrast, the negative treatment effects on alcohol and cigarette use could not be explained by the program's targeted mediators (normative beliefs, refusal skills, consequences, attitudes and intentions). The direct effects of treatment on use for the baseline nonusers of cigarettes and alcohol remain unexplained. CONCLUSIONS: Possible explanations for this pattern and implications for strengthening universal prevention programs that are delivered to both users and nonusers are discussed. The importance of mediational analyses for programs that show negative impacts, as well as for those that show positive impacts is stressed.


Subject(s)
Health Education , Substance-Related Disorders/epidemiology , Substance-Related Disorders/prevention & control , Adolescent , Alcohol Drinking/prevention & control , Communication , Decision Making , Female , Humans , Male , Marijuana Smoking/prevention & control , Models, Psychological , Smoking Prevention , Social Behavior , Socioeconomic Factors , Substance-Related Disorders/psychology , Surveys and Questionnaires , Treatment Outcome
20.
Health Educ Behav ; 36(4): 724-45, 2009 Aug.
Article in English | MEDLINE | ID: mdl-18809689

ABSTRACT

Drawing on the elaboration likelihood model of persuasive communication, the authors examine the impact of the perceptions of the instructor or source on students' receptivity to a new substance abuse prevention curriculum. Using survey data from a cohort of students participating in the Adolescent Substance Abuse Prevention Study, the authors use structural equation modeling to determine the effects of the perceptions students have of their program instructor on measures of the targeted program mediators and the use of cigarettes, alcohol, and marijuana. They test these instructor effects after each component of a two-part curriculum is administered (during the seventh and ninth grades). They find that the perceptions of the instructor significantly affect refusal, communication and decision-making skills, normative beliefs, perceived consequences of use, and substance use. The authors discuss the implications of these findings for school-based prevention programming and indications for further research.


Subject(s)
Attitude , Health Education , Persuasive Communication , Police , Substance-Related Disorders/prevention & control , Adolescent , Alcohol Drinking/adverse effects , Alcohol Drinking/prevention & control , Alcohol Drinking/psychology , Child , Cohort Studies , Communication , Culture , Curriculum , Decision Making , Humans , Longitudinal Studies , Marijuana Abuse/prevention & control , Marijuana Abuse/psychology , Models, Psychological , Ohio , Smoking/adverse effects , Smoking/psychology , Smoking Prevention , Substance-Related Disorders/psychology , Treatment Outcome , Treatment Refusal , Trust
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