Subject(s)
Corynebacterium diphtheriae/isolation & purification , Military Personnel , Germany , Humans , Incidence , MaleSubject(s)
Liver Abscess/therapy , Methicillin Resistance , Military Personnel , Staphylococcal Infections/therapy , Staphylococcus aureus/drug effects , Adult , Anti-Bacterial Agents/pharmacology , Drug Resistance, Multiple , Humans , Liver/injuries , Liver Abscess/microbiology , Male , Rupture , Staphylococcal Infections/microbiology , Staphylococcus aureus/isolation & purification , United KingdomABSTRACT
Clinical and laboratory staff of the Army and RAF medical services at risk of acquiring infection with hepatitis B were immunised against the virus with a recombinant vaccine. Vaccine was administered in Service hospitals and medical centres located throughout the world. After a primary course of vaccine, 73% of personnel developed anti-HBs titres > or = 100 IU/L to hepatitis B surface antigen and were considered protected; 11% were non-responders (anti-HBs < 10 IU/l). A significantly higher proportion of females than males, and vaccinees under 40 years of age, produced a good response. Among those achieving a good response, antibody titres were higher in the younger age group and in females. After a fourth (booster) dose of vaccine, 87.2% of the poor responders and 37% non-responders, developed anti-HBs titres > or = 100 IU/L.
Subject(s)
Hepatitis B Vaccines/immunology , Hepatitis B/immunology , Hepatitis B/prevention & control , Military Personnel , Occupational Diseases/prevention & control , Adolescent , Adult , Aged , Antibodies, Viral/blood , Female , Follow-Up Studies , Hepatitis B Surface Antigens/blood , Hepatitis B Vaccines/administration & dosage , Humans , Immunization, Secondary , Male , Middle Aged , United KingdomABSTRACT
A case of thoracic discitis secondary to a pyodermal skin condition known as 'Woodbury' rash is described.
Subject(s)
Discitis/microbiology , Pyoderma/complications , Staphylococcal Skin Infections/complications , Streptococcal Infections/complications , Streptococcus pyogenes , Superinfection/complications , Thoracic Vertebrae , Adult , Discitis/diagnostic imaging , Discitis/drug therapy , Humans , Male , Military Personnel , RadiographyABSTRACT
Acetic acid was used topically at concentrations of between 0.5% and 5% to eliminate Pseudomonas aeruginosa from the burn wounds or soft tissue wounds of 16 patients. In-vitro studies indicated the susceptibility of P. aeruginosa to acetic acid; all strains exhibited a minimum inhibitory concentration of 2 per cent. P. aeruginosa was eliminated from the wounds of 14 of the 16 patients within two weeks of treatment. Acetic acid was shown to be an inexpensive and efficient agent for the elimination of P. aeruginosa from burn and soft tissue wounds.
Subject(s)
Acetates/therapeutic use , Burns/drug therapy , Pseudomonas Infections/drug therapy , Pseudomonas aeruginosa/drug effects , Skin/injuries , Wound Infection/drug therapy , Acetates/administration & dosage , Acetic Acid , Administration, Topical , Adult , Aged , Burns/microbiology , Drug Evaluation , Female , Humans , Male , Middle Aged , Prospective Studies , Pseudomonas Infections/microbiology , Pseudomonas aeruginosa/isolation & purification , Skin/microbiology , Wound Infection/microbiologySubject(s)
Abdomen/microbiology , Abscess/microbiology , Endocarditis, Bacterial/diagnosis , Lacticaseibacillus casei/isolation & purification , Abscess/diagnosis , Abscess/drug therapy , Aged , Anti-Bacterial Agents/therapeutic use , Diagnosis, Differential , Drug Resistance, Microbial , Endocarditis, Bacterial/drug therapy , Humans , Lacticaseibacillus casei/drug effects , Male , Vancomycin/therapeutic useABSTRACT
The problem of oxygen diffusion into absorbing tissue is complex, and any attempt to model this process involves simplifications of the actual biological processes. Herein is presented a mathematical model of this problem, using cylindrically-shaped sections of tissue. Experimental data has been found for this problem in the literature, and good agreement is obtained for two cases using this model. It is shown that the truncation method is a useful and accurate method for solving oxygen diffusion-absorption problems. Furthermore, if enough experimental data is available, then some conclusions may be made concerning the boundary shapes and the absorption function obtained by modeling this data. These may possibly be used as predictive guidelines for other studies.
