ABSTRACT
Effects have been studied of multimodality treatment on the function of external breathing in patients with disseminated pulmonary tuberculosis using food additives Trace Minerals. Positive dynamics has been recordable of changes in indices for forced lung vital capacity, minute oxygen consumption, both prior and after loading, and maximum volume speed (MVS75) before loading. The obtained data are indicative of the efficacy of using vitamin-mineral additives Trace Minerals evidenced by improvement in bronchial patency and normalization of ventilation-and-perfusion relations in patients with destructive forms of pulmonary tuberculosis.
Subject(s)
Food Additives/therapeutic use , Trace Elements/therapeutic use , Tuberculosis, Pulmonary/therapy , Adult , Bronchi/physiopathology , Combined Modality Therapy , Food Additives/administration & dosage , Forced Expiratory Flow Rates , Forced Expiratory Volume , Humans , Middle Aged , Oxygen Consumption , Respiratory Function Tests , Trace Elements/administration & dosage , Tuberculosis, Pulmonary/physiopathology , Vital CapacityABSTRACT
The content was studied of vasoactive intestinal peptide (VIP), substantia P (SP), bombesine (BMB), prostaglandins (PG) E2, F2alpha, 6-keto-F1alpha, Tx A2, and leukotrien (LT) B4 in the expired air condensate with the aid of the radioimmune technique to reveal a relation between pulmonary tachykinins and eicosanoids in obstructive type respiratory incompetence in patients with pulmonary tuberculosis. In patients with pulmonary tuberculosis, a high level of BMB was measurable in the expired air condensate. A linear negative correlation has been established between BMB content and forced expiratory volume, SP and respiratory volume, SP and lung capacity. In pulmonary tuberculosis, PGE2 and PGF2alpha levels are significantly evaluated. There was a positive correlation between BMB content and PGF2a in the expired air condensate, which fact suggests their synergic action on the smooth muscles of the bronchi and bronchioles.
