ABSTRACT
The medical records of 11 Cavalier King Charles spaniels with idiopathic, asymptomatic thrombocytopenia and large-to-giant platelets were identified from a 10-year retrospective search using the Veterinary Medical Data Base at Purdue University. Eight of the dogs had been treated with various immunosuppressive drugs. Six of the treated dogs remained thrombocytopenic, one was not reevaluated, and one developed a normal platelet count. The underlying etiology of idiopathic, asymptomatic thrombocytopenia in Cavalier King Charles spaniels has not been identified, but this condition could represent a congenital macrothrombocytopenic disorder.
Subject(s)
Dog Diseases/epidemiology , Thrombocytopenia/veterinary , Animals , Blood Platelets/pathology , Breeding , Dog Diseases/blood , Dog Diseases/drug therapy , Dogs , Female , Immunosuppressive Agents/therapeutic use , Incidence , Male , Prednisone/therapeutic use , Retrospective Studies , Thrombocytopenia/epidemiology , Thrombocytopenia/geneticsSubject(s)
Dog Diseases/diagnosis , Hyphema/veterinary , Uveitis/diagnosis , Uveitis/veterinary , Animals , Dog Diseases/drug therapy , Dogs , Glucocorticoids/therapeutic use , Hyphema/complications , Hyphema/diagnosis , Hyphema/drug therapy , Male , Prednisone/therapeutic use , Retinal Hemorrhage/complications , Retinal Hemorrhage/diagnosis , Retinal Hemorrhage/veterinary , Uveitis/complications , Uveitis/drug therapyABSTRACT
A two-year-old, neutered male Labrador retriever was anesthetized with intravenous propofol for bronchoscopy to remove a bronchial foreign body. The dog previously had been diagnosed with idiopathic epilepsy. During anesthetic recovery, the dog exhibited excitatory movements characterized by forelimb extensor rigidity, opisthotonos, generalized tremors, paddling, horizontal nystagmus, and facial twitching. Intravenous administration of pentobarbital temporarily stopped the motor activity. The excitatory movements persisted for 20 hours. The dog went on to recover completely, although he remained an epileptic, having one brief, generalized grand mal seizure every three-to-four months.
