ABSTRACT
Cardiointervalometry was used to investigate functional parameters of the cardiorespiratory system during text reading. A total of healthy women aged from 17 to 28 years and 11 women with hypotonic dysphonia 17 to 31 years of age entered the study. Both groups exhibited a low index of parasympathetic component of cardiorhythm regulation in shortening of the RR-interval. Correlation inhalation/expiration has changed with prolongation of inhalation and shortening of expiration in reading in women suffering from hypotonic dysphonia. Parameters of the respiratory cycle at rest did not correlate with relevant parameters in reading text in both groups.
Subject(s)
Heart Rate/physiology , Muscle Hypotonia/epidemiology , Muscle Hypotonia/physiopathology , Respiration Disorders/epidemiology , Voice Disorders/epidemiology , Voice Disorders/physiopathology , Adolescent , Adult , Female , Humans , Laryngeal Muscles/physiopathology , Vagus Nerve/physiology , Voice Disorders/diagnosisSubject(s)
Respiration , Vocal Cords/physiology , Voice/physiology , Adolescent , Adult , Breath Tests , Bronchi/physiology , Female , Humans , Male , Phonetics , Sex FactorsSubject(s)
Blood Donors , Immunization , Leukapheresis , Plasmapheresis , Staphylococcal Toxoid/immunology , HumansABSTRACT
Analysis of the socioeconomic effectiveness of the use of immune antimeningococcal plasma in patients with the grave patterns of meningococcal infection has shown that introduction of the preparation into multimodality therapy results not only in a considerable medicosocial effect (reduction of lethality, lowering of the patients' stay at a hospital, a more rapid, as compared with the control group, removal of the symptoms of intoxication, elimination of hemodynamic disorders underlying the infectious toxic shock) but also in an appreciable economic effect.
Subject(s)
Immune Sera/administration & dosage , Immunization, Passive/economics , Meningococcal Infections/therapy , Neisseria meningitidis/immunology , Child , Cost-Benefit Analysis , Humans , Meningococcal Infections/economics , RussiaSubject(s)
Antibodies, Bacterial/blood , Blood Bactericidal Activity , Immunization , Adolescent , Adult , Female , Humans , Male , Middle AgedSubject(s)
Meningococcal Infections/therapy , Neisseria meningitidis/immunology , Plasma/immunology , Antibodies, Bacterial/administration & dosage , Antibodies, Bacterial/analysis , Child, Preschool , Combined Modality Therapy , Drug Evaluation , Humans , Infant , Leukocyte Count , Male , Meningococcal Infections/immunology , Time FactorsABSTRACT
In patients with a severe course of suppurative lactation mastitis there develops a relative deficiency in the cellular and humoral links of immunity. The compensatory activation of factors of nonspecific antiinflammatory resistance of the organism fails to exert a substantial positive effect on the development of the destructive process in these patients. On the basis of the data obtained, in order to improve results of the surgical treatment of patients with suppurative lactation mastitis means of the cellular anti-infection therapy, transfusions of donor leukocyte masses in particular, must be included in the complex of curative measures in the postoperative period.
Subject(s)
Leukocytes/physiology , Mastitis/immunology , Puerperal Infection/immunology , Antibody Formation , Cell Movement , Female , Humans , Immunity, Cellular , Leukocyte Count , Phagocytosis , Pregnancy , Rosette FormationABSTRACT
Use in the composition of complex therapy of patients suffering from chronic lympholeukemia of antilymphocytic immunoglobulin with an associated antibacterial activity aided normalization of the leukocytic differential count and prevented development of inflammatory and septic complications in these patients.
Subject(s)
Anti-Infective Agents , Antilymphocyte Serum/therapeutic use , Leukemia, Lymphoid/drug therapy , Anemia, Hemolytic, Autoimmune/drug therapy , Antilymphocyte Serum/administration & dosage , Autoimmune Diseases/drug therapy , Clinical Trials as Topic , Drug Evaluation , Female , Humans , Immunity/drug effects , Immunity, Innate/drug effects , Leukemia, Lymphoid/complications , Leukemia, Lymphoid/immunology , MaleABSTRACT
Immunoglobulin was obtained from rabbit sera following immunization of the animals with a complex antigen composed of a suspension of human thymocytes and killed microbe polyvaccine. The preparation possessed not only antilymphocytic activity in vitro, but also protected the animals after their artificial infection.
Subject(s)
Antilymphocyte Serum/isolation & purification , Immunoglobulins/isolation & purification , Animals , Antigens/administration & dosage , Antilymphocyte Serum/administration & dosage , Bacterial Infections/prevention & control , Clone Cells/immunology , Drug Evaluation, Preclinical , Epitopes , Humans , Immunization , Immunoglobulins/administration & dosage , Immunosuppression Therapy , Lymphocytes/immunology , Mice , Rabbits , Transplantation ImmunologyABSTRACT
In sera of patients with acute leucosis the authors have determined antibodies to alpha-toxin, streptolysin-O, the complement, lysosyme. B-lysins and C-reactive protein. It was found that the indices of immune reactivity in patients with acute leucosis are dependent on a morphological variant of the disease, the duration of the conducted therapy and presence of complications. The most high immunity indices in patients with acute leucosis were observed in a primary active stage of the disease and during the period of remission. Considerable reduction of the immunity was noted in the terminal stage of the disease.
