ABSTRACT
The article discusses the main, modern provisions of the programs of medical and social rehabilitation of patients with occupational diseases of the ENT organs. The criteria of the degree of loss of professional ability to work in hearing loss and malignant neoplasms of the upper respiratory tract are presented. Rehabilitation programs and forms are developed taking into account the needs of the victim in medical, social and vocational rehabilitation, taking into account the potential capabilities and abilities of the victim to carry out professional, domestic and social activities.
Subject(s)
Deafness , Larynx , Occupational Diseases , Humans , Occupational Diseases/diagnosis , Occupational Diseases/etiology , Nose , TracheaSubject(s)
Cholestasis/physiopathology , Cytoprotection , Jaundice, Obstructive/physiopathology , Liver/physiopathology , S-Adenosylmethionine/administration & dosage , Succinates/administration & dosage , Animals , Cholestasis/complications , Cholestasis/pathology , Disease Models, Animal , Jaundice, Obstructive/etiology , Jaundice, Obstructive/pathology , Liver/drug effects , Liver/pathology , Male , Rats , Rats, WistarABSTRACT
Remaxol is a new infusion hepatoprotector that contains succinic acid, inosine, methionine and methylglucamine. The hepatoprotective effect of remaxol on the liver function has been studied on the model of obstructive jaundice in rats, on the terms of one and two weeks after ligation of the common bile duct (M. A. Aller, et al., 2004). Sixty rats were randomly divided into six groups: sham-operated rats with cholestasis, 0.9% NaCl treated rats with cholestasis, and remaxol treated rats with cholestasis, all on the one week (per os n=10) and two weeks (n=10) terms. Remaxol was injected into the tail vein in a dose of 1 ml/100 g during the first week after the induction of cholestasis. The rats were removed from the experiment after one and two weeks of postoperative period, respectively. The size and weight of the liver and the degree of ascites were measured, and the blood samples were taken to analyze for bilirubin, alkaline phosphatase, gamma-glutamyl transpeptidase, alanineaminotransferase, aspartataminotransferase. Morphological changes in the liver were also studied. The biochemical parameters of blood and morphological evolution of tissue of liver in both one and two weeks after the induction of cholestasis showed a significant hepatoprotective effect of remaxol.
