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Ter Arkh ; 70(3): 29-32, 1998.
Article in Russian | MEDLINE | ID: mdl-9575584

ABSTRACT

AIM: Assessment of the effect of a new Russian selective sympathomimetic salben (powder for inhalations) on bronchial secretion viscosity and adhesion. MATERIALS AND METHODS: Salben or placebo (sodium bensoate) were given to 82 and 30 patients (control) with bronchial asthma, respectively. The response was assessed by clinical, laboratory and instrumental findings. RESULTS: A statistically significant (p < 0.05) reduction of the viscosity and adhesion (by 15 and 20%, respectively) was noted in the salben group which also demonstrated improved external respiration. CONCLUSION: Salben induced positive effect on bronchial secretion viscosity and adhesion.


Subject(s)
Albuterol/pharmacology , Bronchi/drug effects , Bronchi/metabolism , Bronchodilator Agents/pharmacology , Expectorants/pharmacology , Sympathomimetics/pharmacology , Administration, Inhalation , Adult , Aged , Albuterol/administration & dosage , Asthma/drug therapy , Asthma/physiopathology , Benzoates/administration & dosage , Benzoates/pharmacology , Benzoic Acid , Bronchodilator Agents/administration & dosage , Double-Blind Method , Drug Combinations , Expectorants/administration & dosage , Female , Humans , Male , Middle Aged , Powders , Sputum/drug effects , Sputum/metabolism , Sympathomimetics/administration & dosage , Viscosity/drug effects
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