Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Emerg Infect Dis ; 22(4): 590-7, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26982243

ABSTRACT

We evaluated clinical Shiga toxin-producing Escherichia coli O157 infections in England and Wales during 1983-2012 to describe changes in microbiological and surveillance methods. A strain replacement event was captured; phage type (PT) 2 decreased to account for just 3% of cases by 2012, whereas PT8 and PT21/28 strains concurrently emerged, constituting almost two thirds of cases by 2012. Despite interventions to control and reduce transmission, incidence remained constant. However, sources of infection changed over time; outbreaks caused by contaminated meat and milk declined, suggesting that interventions aimed at reducing meat cross-contamination were effective. Petting farm and school and nursery outbreaks increased, suggesting the emergence of other modes of transmission and potentially contributing to the sustained incidence over time. Studies assessing interventions and consideration of policies and guidance should be undertaken to reduce Shiga toxin-producing E. coli O157 infections in England and Wales in line with the latest epidemiologic findings.


Subject(s)
Disease Outbreaks , Escherichia coli Infections/epidemiology , Escherichia coli O157/metabolism , Shiga Toxin/isolation & purification , Shiga-Toxigenic Escherichia coli/metabolism , Adolescent , Adult , Animals , Child , Child, Preschool , Coliphages/classification , Coliphages/genetics , Coliphages/isolation & purification , Communicable Disease Control , England/epidemiology , Epidemiological Monitoring , Escherichia coli Infections/microbiology , Escherichia coli Infections/pathology , Escherichia coli Infections/transmission , Escherichia coli O157/isolation & purification , Escherichia coli O157/pathogenicity , Escherichia coli O157/physiology , Feces/microbiology , Female , Humans , Incidence , Infant , Infant, Newborn , Male , Meat/microbiology , Middle Aged , Milk/microbiology , Molecular Typing , Shiga Toxin/biosynthesis , Shiga-Toxigenic Escherichia coli/pathogenicity , Shiga-Toxigenic Escherichia coli/physiology , Wales/epidemiology
SELECTION OF CITATIONS
SEARCH DETAIL
...