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1.
Micromachines (Basel) ; 14(5)2023 Apr 25.
Article in English | MEDLINE | ID: mdl-37241548

ABSTRACT

In this paper, the behavior of the Bi-Material Cantilever (B-MaC) response deflection upon fluidic loading was experimentally studied and modeled for bilayer strips. A B-MaC consists of a strip of paper adhered to a strip of tape. When fluid is introduced, the paper expands while the tape does not, which causes the structure to bend due to strain mismatch, similar to the thermal loading of bi-metal thermostats. The main novelty of the paper-based bilayer cantilevers is the mechanical properties of two different types of material layers, a top layer of sensing paper and a bottom layer of actuating tape, to create a structure that can respond to moisture changes. When the sensing layer absorbs moisture, it causes the bilayer cantilever to bend or curl due to the differential swelling between the two layers. The portion of the paper strip that gets wet forms an arc, and as the fluid advances and fully wets the B-MaC, the entire B-MaC assumes the shape of the initial arc. This study showed that paper with higher hygroscopic expansion forms an arc with a smaller radius of curvature, whereas thicker tape with a higher Young's modulus forms an arc with a larger radius of curvature. The results showed that the theoretical modeling could accurately predict the behavior of the bilayer strips. The significance of paper-based bilayer cantilevers lies in their potential applications in various fields, such as biomedicine, and environmental monitoring. In summary, the novelty and significance of paper-based bilayer cantilevers lie in their unique combination of sensing and actuating capabilities using a low-cost and environmentally friendly material.

2.
Micromachines (Basel) ; 13(9)2022 Sep 09.
Article in English | MEDLINE | ID: mdl-36144125

ABSTRACT

The novel paper-based Bi-Material Cantilever (B-MaC) valve allows the autonomous loading and control of multiple fluid reagents which contributes to the accurate operation of paper-based microfluidic devices utilized for biological and chemical sensing applications. In this paper, an extensive parametric study is presented to evaluate the effects of key geometric parameters of the valve, such as paper direction, cantilever width, paper type, tape type, and sample volume, in addition to the effects of relative humidity and temperature on the functionality of the B-MaC and to provide a better understanding of the rate of fluid flow and resulting deflection of the cantilever. Machine direction, cantilever width, paper type, and tape type were found to be important parameters that affect the B-MAC's activation time. It was also observed that the rate of fluid imbibition in the B-MaC is considerably affected by change in humidity for high (55 °C) and low (25 °C) temperatures, while humidity levels have no significant effect during imbibition in the B-MaC at an ambient temperature of 45 °C. It was also found that a minimum distance of 4 mm is required between the B-MaC and the stationary component to prevent accidental activation of the B-MaC prior to sample insertion when relative humidity is higher than 90% and temperature is lower than 35 °C. The rate of fluid imbibition that determines the wetted length of the B-MaC and the final deflection of the cantilever are critical in designing and fabricating point-of-care microfluidic paper-based devices. The B-MaC valve can be utilized in a fluidic circuit to sequentially load several reagents, in addition to the sample to the detection area.

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