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Vestn Oftalmol ; 140(2. Vyp. 2): 94-101, 2024.
Article in Russian | MEDLINE | ID: mdl-38739137

ABSTRACT

This case report presents the diagnostic features of isolated primary intraocular lymphoma, which was initially misdiagnosed as neovascular age-related macular degeneration. A comprehensive examination using ultrasound, optical coherence tomography, and fundus autofluorescence revealed changes characteristic of vitreoretinal lymphoma. Molecular genetic analysis of the vitreous body showed the presence of a MYD88 gene mutation and B-cell clonality by immunoglobulin heavy chain (IGH) gene rearrangement tests, which confirmed the diagnosis.


Subject(s)
Retinal Neoplasms , Tomography, Optical Coherence , Vitreous Body , Humans , Vitreous Body/pathology , Vitreous Body/diagnostic imaging , Retinal Neoplasms/diagnosis , Tomography, Optical Coherence/methods , Diagnosis, Differential , Intraocular Lymphoma/diagnosis , Male , Myeloid Differentiation Factor 88/genetics , Fluorescein Angiography/methods , Aged , Eye Neoplasms/diagnosis
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