1.
J Med Chem
; 19(11): 1290-4, 1976 Nov.
Article
in English
| MEDLINE
| ID: mdl-63551
ABSTRACT
A series of polyhedral borane derivatives containing protein-binding functional groups has been synthesized. Problems encountered in earlier studies (low incorporation levels, gross precipitation of conjugates) have been overcome by including a water-solubilizing gluconamide group in the structure. This modification has allowed high levels of boron to be covalently bound to HGG, forming a completely water-soluble conjugate.