[Oral cavity microbial coenobia in healthy children and children with chronic recurrent aphthous stomatitis]. / Osoblyvosti mikrobiotsenozu rotovoï porozhnyny u zdorovykh ditei ta khvorykh na khronichnyi retsydyvnyi aftoznyi stomatyt.

Peculiarities of quantitative and qualitative composition of microbiocenosis of the oral cavity in healthy children and children with chronic aphthous recurrent stomatitis have been studied. Strains of microorganisms (n = 259) have been isolated and identified. The results obtained showed that the studied biotope is characterised by a wide spectrum of isolated microflora. The growth of microorganism association is observed in all the studied samples. The analysis of genus and species composition of microbiocenosis of the mucous membrane indicated that streptococci, neiserii, corynebacteria, enterococci, lactobacilli, epidermal staphylococci and candidas were distinguished as to isolation frequency among the isolated strains. These bacteria were isolated from oral cavity of healthy and sick children, but their quantity in 1 mm2 of sick children mucosa prevailed, except for Streptococcus salivarius, S. mitis and Lactobacillus sp.: their quantity was far less. Golden staphylococci, escherichia, klebsiella, clostridia, hemophilic rods and campylobacteria were isolated from sick children only.

[Investigation of the activity of the preparation cerbiden against Candida spp]. / Doslidzhennia aktyvnosti preparatu tserbidenu shchodo Candida spp.

Antifungal activity of a new complex antibiotical preparation cerbiden obtained from medical plant Bidens cernua L. of the Asteraceae family, was investigated in vitro against the clinical and museum strains of Candida spp. High cerbiden activity against clinical and museum strains of Candida albicans, C. tropicalis, C. krusei, C. parapsilosis, C. guilliermondii, sensitive and resistant to nystatin, amphotericin B and clotrimazole was determined.