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1.
J Laryngol Otol ; 126(3): 260-6, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22017979

ABSTRACT

OBJECTIVES: This study aimed to analyse demographic profiles and pre-injection stroboscopic findings for patients with unilateral vocal fold paralysis, to investigate possible predictive factors for voice outcomes of injection laryngoplasty. MATERIALS AND METHODS: Fifty-nine unilateral vocal fold paralysis patients underwent vocal fold augmentation, using transcutaneous Artecoll (polymethyl methacrylate microspheres plus bovine collagen) injection into the paralysed vocal fold via the cricothyroid space. Three months later, patients were divided into improved (n = 44) and unimproved (n = 15) groups, using the perceptual grade-roughness-breathiness-asthenia-strain scale, and their clinical characteristics and pre-operative stroboscopic findings compared. RESULTS: The improved group were significantly younger than the unimproved group (p = 0.000). The size of the posterior gap on phonation was closely associated with the outcome of injection laryngoplasty (p = 0.015). CONCLUSION: Younger patients with a smaller posterior glottic gap on phonation can be expected to have a more favourable outcome following injection laryngoplasty for correction of glottic insufficiency due to unilateral vocal fold paralysis.


Subject(s)
Glottis/pathology , Laryngoplasty/methods , Vocal Cord Paralysis/surgery , Voice Disorders/surgery , Voice Quality/physiology , Adult , Age Factors , Aged , Animals , Cattle , Collagen/administration & dosage , Collagen/therapeutic use , Female , Glottis/physiopathology , Glottis/surgery , Humans , Injections , Logistic Models , Male , Microspheres , Middle Aged , Phonation/physiology , Polymethyl Methacrylate/administration & dosage , Polymethyl Methacrylate/therapeutic use , Stroboscopy , Treatment Outcome , Vocal Cord Paralysis/physiopathology , Voice Disorders/physiopathology
2.
J Laryngol Otol ; 123(7): 807-10, 2009 Jul.
Article in English | MEDLINE | ID: mdl-18808728

ABSTRACT

OBJECTIVE: Local extension of thyroid carcinoma can result in massive invasion of the trachea, causing severe airway compromise. The pre- and peri-operative management of such airway compromise is difficult but critical. We report the use of extracorporeal oxygenation support as an alternative peri-operative airway management option in such a situation. This approach facilitated curative surgery in a patient with papillary thyroid carcinoma invading the trachea. METHOD: We present a case report regarding extracorporeal oxygenation support in a patient with locally advanced thyroid carcinoma. RESULTS: The patient was a 68-year-old woman with aggressive thyroid papillary carcinoma invading the trachea. The airway was almost totally obstructed, and tracheal resection and end-to-end anastomosis was planned. A venovenous bypass catheter was placed for cardiopulmonary bypass, using the bilateral femoral veins. Curative surgery and reconstruction were then performed successfully, under general anaesthesia assisted by cardiopulmonary bypass oxygenation. CONCLUSION: Cardiopulmonary bypass oxygenation is a safe and effective alternative airway management option in patients with locally aggressive thyroid cancer.


Subject(s)
Carcinoma, Papillary/pathology , Extracorporeal Membrane Oxygenation/methods , Thyroid Neoplasms/pathology , Tracheal Neoplasms/pathology , Aged , Carcinoma, Papillary/surgery , Female , Humans , Neoplasm Invasiveness , Thyroid Neoplasms/surgery , Tomography, X-Ray Computed
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