ABSTRACT
Fibroma of the tendon sheath is an uncommon soft tissue tumor presenting as a solitary, slow-growing, firm, painless, small nodule, which shows strong attachment to the tendon or tendon sheath. It is usually localized on fingers and hand tendons in adults between the age of 20 and 40 years old. This case concerns a 61-year-old man presenting with a 5-year history of multiple cutaneous nodules on both palms and soles. Skin biopsy confirmed fibroma of the tendon sheath. Blood tests showed a high titer of rheumatoid factor and positivity to anti-nuclear antibody. No case of fibroma of the tendon sheath occurring multifocally on both palms and soles has been previously reported. Herein, we report on a very rare case of multiple fibromas of the tendon sheath arising from palms and soles, which supports the pathogenetic hypothesis that this tumor may be a reactive process rather than a true neoplasm.
Subject(s)
Adult , Humans , Middle Aged , Biopsy , Fibroma , Fingers , Hand , Hematologic Tests , Rheumatoid Factor , Skin , TendonsABSTRACT
BACKGROUND: Dermatological diseases can occur with atopic dermatitis. OBJECTIVE: The purpose of this study was to analyze diseases associated with atopic dermatitis in Koreans. METHODS: From November, 2007, to May, 2008, 948 patients with atopic dermatitis who visited the department of dermatology at 19 hospitals were evaluated for associated diseases. RESULTS: Of 948 patients, 53.8% (510) had symptoms associated with other dermatological diseases. In order of frequency, diseases associated with atopic dermatitis included acne, hand/foot eczema, seborrheic dermatitis, urticaria, warts, and recurrent herpes simplex. The number of associated diseases did not change significantly with the severity of atopic dermatitis. However, the incidence of hand/foot eczema and eczema herpeticum correlated significantly with the severity of atopic dermatitis. CONCLUSION: There is a distinct pattern of diseases associated with atopic dermatitis in Koreans.
Subject(s)
Humans , Acne Vulgaris , Dermatitis, Atopic , Dermatitis, Seborrheic , Dermatology , Eczema , Herpes Simplex , Incidence , Kaposi Varicelliform Eruption , Methylmethacrylates , Polystyrenes , Urticaria , WartsABSTRACT
No abstract available.
Subject(s)
Follow-Up Studies , Itraconazole , Nails , Onychomycosis , RecurrenceABSTRACT
Pyomyositis is an acute, suppurative bacterial infection of striated muscle. It occurs primarily, and not from contiguous infection. It is considered rare in temperate climates. There has been no report of pyomyositis in the Korean dermatologic literature to date. We report a case of pyomyositis which developed in a 53-year-old male. The patient was admitted for the treatment of cutaneous leukocytoclastic vasculitis on his entire body. He was treated with oral corticosteroids for approximately three weeks. The skin condition did show improvement; however, the patient developed a persistent fever and a newly-found mass on the right upper back. The mass was diagnosed as an abscess, replacing the striated muscles of the back by sono-guided needle aspiration. After surgical intervention and IV antibiotic treatment, the symptoms and mass on the back disappeared. We speculate that the underlying skin condition and long-term use of oral corticosteroids predisposed the patient to pyomyositis.
Subject(s)
Humans , Male , Middle Aged , Abscess , Adrenal Cortex Hormones , Bacterial Infections , Climate , Fever , Muscle, Striated , Needles , Pyomyositis , Skin , Vasculitis, Leukocytoclastic, CutaneousABSTRACT
BACKGROUND: Sarcoidosis is a systemic noncaseating granulomatous disorder of unknown origin, which can involve any organs including the skin. OBJECTIVE: The purpose of this study is to investigate the clinical characteristics of sarcoidosis in patients in Seoul and Gyeonggi-do. METHODS: A total of 62 patients with sarcoidosis, where sarcoidosis was confirmed by histopathologic examinations at seven university hospitals in Seoul and Gyeonggi-do from 2000 to 2006, were enrolled in this study. The clinical characteristics were analyzed by a thorough review of medical records, histopathologic and radiologic examinations. RESULTS: Man to woman ratio was 1 : 1.48 and 42% of the patients were in their fifth decade. The most frequent chief complaints were cutaneous symptoms (37%), followed by respiratory symptoms (31%). The most frequently involved organs were intrathoracic organs (84%), followed by the skin (37%), peripheral lymph nodes (13%), bones (11%), spleen (8%) and eyes (5%). The most common cutaneous lesion was subcutaneous nodule (74%), followed by papule (13%). Extremities (65%) were the most frequent sites of cutaneous lesions. Systemic organ involvements were observed in 70% of patients with cutaneous sarcoidosis. Among them, the most frequently involved organs were intrathoracic organs (81%), followed by bones (25%), eyes (19%), and peripheral lymph nodes (19%). CONCLUSION: The results were generally similar with the previous domestic reports. Compared with the foreign reports, cutaneous involvement was more frequent and ophthalmic involvement was less frequent. Subcutaneous nodule was the most frequent cutaneous lesion which seems to be a unique feature of this study.
Subject(s)
Female , Humans , Extremities , Hospitals, University , Lymph Nodes , Medical Records , Sarcoidosis , Seoul , Skin , SpleenABSTRACT
BACKGROUND: Pitted keratolysis is a superficial bacterial infection which usually affects the pressure bearing areas of the feet. Some bacterial organisms were identified as etiologic agents, including Corynebacterium species, Micrococcus species and Dermatophilus congolensis. However, in Korea, studies to prove the causative organisms have not been performed. OBJECTIVE: We performed this study to identify causative organisms of pitted keratolysis in Korea. METHOD: Twelve normal healthy men and 27 pitted keratolysis patients were enrolled. We cultured the scraped specimens of the stratum corneum and identified the cultured organisms. We compared the cultured organisms of pitted keratolysis group with those of control group. We also compared the distribution of cultured organisms in pitted keratolysis with and without tinea pedis. RESULT: Micrococcus species and Corynebacterium species were identified in pitted keratolysis group much more frequently than in normal control group. In most cases of pitted keratolysis combined with tinea pedis, the identified organisms were Micrococcus species. CONCLUSION: Micrococcus species and Corynebacterium species are thought to be the major causative organisms of pitted keratolysis in Korea. Micrococcus species might play a certain antagonistic role, especially in patients of pitted keratolysis with tinea pedis.
Subject(s)
Humans , Male , Bacterial Infections , Corynebacterium , Foot , Korea , Micrococcus , Tinea PedisABSTRACT
BACKGROUND: The number of patients infected with human immunodeficiency virus (HIV) in Korea has increased steadily. Cutaneous disorders are common during the course of HIV disease as a result of the acquired immunodeficiency or are related to treatment. However, there have only been a few studies on cutaneous disease in HIV infected patients in Korea. OBJECTIVE: The aim of the study was to investigate the characteristics of cutaneous disease in HIV infected patients in Korea. METHODS: We surveyed questionnaires answered by 35 human immunodeficiency virus (HIV) infected patients. Clinical data was also collected through physical examination by a dermatologist and, if available, medical records were reviewed. RESULTS: The most frequent and persistent cutaneous disease in HIV infected patients in Korea was seborrheic dermatitis. Oral candidiasis, folliculitis, condyloma accuminata, and syphilis were also common. About 30% of patients who received antiretroviral treatment complained of adverse drug effects related to antiretroviral treatment. There was a positive correlation between the duration of HIV infection and the frequency of cutaneous disorders. CONCLUSION: We found that HIV infected patients want to have more information on cutaneous disorders associated with HIV infection. The patient education should be focused on seborrheic dermatitis, oral candidiasis, folliculitis, condyloma acuminata, syphilis, and the adverse drug effects associated with antiretroviral treatment.
Subject(s)
Humans , Candidiasis, Oral , Dermatitis, Seborrheic , Folliculitis , HIV Infections , HIV , Korea , Medical Records , Patient Education as Topic , Physical Examination , Surveys and Questionnaires , Skin Diseases , SyphilisABSTRACT
BACKGROUND: Recently, the use of cellular phones has greatly increased, and allergic contact dermatitis (ACD) ascribed to the use of cellular phones has been one of the problems. OBJECTIVE: The purpose of this study was to evaluate clinical characteristics of allergic contact dermatitis due to cellular phone use. METHODS: Three male and 7 female patients who were diagnosed as ACD due to cellular phone use were evaluated. A patch test was performed on the upper back and any history of metal allergy was checked. We also evaluated the content of nickel in the cellular phones currently being sold on the market, using a dimethylglyoxime spot test. RESULTS: The results of this study are summarized as follows; There was female predominance in cellular phone dermatitis with an average onset of age 27.4 years old. A history of metal allergy was found in 40.0% of the patients. The most common site and mobile phone type were cheek (60.0%) and slider type (60.0%), respectively. In addition to erythematous patches, itching was accompanied in 60.0% of the patients. But the other patients did not report any pruritus at all. Except in three cases, patch tests were performed on the upper back. Five patients were positive to nickel and 4 patients were positive to chrome. The dimethylglyoxime test showed 21.2% positivity in 104 cellular phones of 27 different models. CONCLUSION: Cellular phone dermatitis usually occurs on both cheeks, or the dominant hand-sided cheek area. The causative metals are mostly nickle and chrome.
Subject(s)
Female , Humans , Male , Cell Phone , Cheek , Dermatitis , Dermatitis, Allergic Contact , Hypersensitivity , Korea , Metals , Nickel , Patch Tests , PruritusABSTRACT
The increased aging of the population in the developed world is an accepted fact. Consequently, the number of patients aged 90 years or above (super-old age: from 90 to 99), and centenarians (above 100) will increase in the coming years. The objective was to determine the prevalence and characteristics of skin diseases in the population of super-old ages and centenarians. A total of 50 volunteers, aged from 90 to 106 years, were enrolled on this study. They completed a questionnaire about skin diseases and underwent a cutaneous examination during the period of July 26 to 30, and Aug 23 to 28, 2004. The average age of the volunteers was 96.3 years. 28 volunteers were women and 22 were men. The common diseases were found to be senile lentigo, seborrheic keratosis, idiopathic guttate hypomelanosis, xerosis, telangiectasia, onychomycosis, tinea pedis, and cherry hemangioma. Wrinkle grading of men was less severe than in women. The degree of pigmentation was independent of age and sex. However, activity and pigmentation scale showed a significant statistical correlation. Gray hair and alopecia in men was more severe than in women. As for aging factors, smoking, activity, location, and occupation did not appear to play an important role in wrinkle formation. The incidence of skin disorders increased with age, due to changes in skin structure and lifelong exposure to environmental aggravations. Super-old aged people often have many skin diseases. However, only a small number of volunteers were included in this study. Therefore, further dermatologic studies need to be conducted.
Subject(s)
Aged, 80 and over , Female , Humans , Male , Aging , Alopecia , Hair , Hemangioma , Hypopigmentation , Incidence , Keratosis, Seborrheic , Lentigo , Occupations , Onychomycosis , Pigmentation , Prevalence , Prunus , Skin Diseases , Skin , Smoke , Smoking , Telangiectasis , Tinea Pedis , Volunteers , Surveys and QuestionnairesABSTRACT
BACKGROUND: Pitted keratolysis (PK) is a bacterial infection of the stratum corneum. The infection is characterized by 1 to 7 mm discrete and coalescing craterlike pits on the plantar surfaces of the feet and toes, especially the weight-bearing areas. Topically applied antibiotics such as clindamycin, benzoyl peroxide erythromycin, and clotrimazole are curative. OBJECTIVE: We performed this study to compare treatment efficacy of benzoyl peroxide (BP) and clindamycin phosphate (CP) in PK. METHOD: The clinical study was made in 44 patients with PK. Among 44 patients, 17 patients were treated by BP topical application alone, 15 patients treated by CP. And the others by combined topical application of BP and CP. RESULT: There were no significant differences in the treatment efficacy between BP and CP, and between monotherapy and combination therapy, neither. 1) Gender ratio showed extreme male predominance (M: F = 43: 1), and the mean age of onset was 22 years old. 2) Mean disease duration was 2.8 months and mean period for complete cure was 2.6 weeks. And there was no significant relation between disease duration and mean period for complete cure. 3) Hyperhidrosis (18.1%) was the most commonly associated condition with PK. The followings were Tinea pedis (13.6%), T. cruris (6.8%), erythrasma (6.8%), cellulitis (6.8%), osmidrosis (6.8%), wart (6.8%), and corn (6.8%) in the order of frequency. 4) There was no statistically significant difference in the treatment efficacy between BP and CP (p> 0.05). 5) Among 44 patients, irritation was observed in 4 cases (9.1%). Two cases were related with BP, and the others with CP. But these adverse effects were trivial and disappeared soon. 6) Four cases (9.1%) showed recurrence within 3 month-follow up. And they were all related with hyperhidrosis. There was no statistically significant difference in the recurrence rate between BP and CP, although patients treated with CP showed slightly higher recurrence rate (p> 0.05). CONCLUSION: Our study shows that no significant difference in the treatment efficacy between benzoyl peroxide and clindamycin phosphate, and between monotherapy and combined therapy, neither. Therefore, combination therapy should be spared for only intractable PK.
Subject(s)
Humans , Male , Young Adult , Age of Onset , Anti-Bacterial Agents , Bacterial Infections , Benzoyl Peroxide , Cellulitis , Clindamycin , Clotrimazole , Erythrasma , Erythromycin , Foot , Hyperhidrosis , Recurrence , Tinea Pedis , Toes , Treatment Outcome , Warts , Weight-Bearing , Zea maysABSTRACT
Intravascular papillary endothelial hyperplasia(IPEH) is a solitary slowly enlarging, often tender, blue to red elevated nodule. The predilection sites include the head and neck region, and the extremities, especially the fingers. Histologically, IPEH is characterized by the well-circumscribed intravascular papillary structures, which are formed by fibrous cores that are lined by endothelial cells. We report a case of intravascular papillary endothelial hyperplasia developed on the unusual site of lip.
Subject(s)
Endothelial Cells , Extremities , Fingers , Head , Hyperplasia , Lip , NeckABSTRACT
BACKGROUND: Dermatologic practice occurs mainly in the outpatient setting. The reasons for, frequency, and impact of inpatient dermatologic consultation may be quite different from outpatient practice and there has been a lot of changes in dermatologic consultation recently. Several studies about characteristics of dermatologic consultation have been reported. OBJECTIVE: The purpose of this study was to examine the characteristics of inpatient dermatologic consultation in Ewha womans university hospital for 3 years and also to compare the result of the report in 1991. METHODS: During a period of 3 years (1996.2-1998.3), we prospectively recorded the demographics of the patients for whom consultation was requested, the final diagnosis of the dermatologic service, and the tests necessary to arrive at diagnosis, and reasons for dermatologic consultation. RESULTS: 1) The consulted patients were 1019 among 38,402 inpatients (2.7%). 2) The total number of male and female patients were 547(53.7%) and 472(46.3%), respectively (M:F = 1.2:1). 3) The most frequent age group was the 6th decade(18.4%) and the highest incidence of seasonal distribution was spring. 4) The patients in internal medicine were the most frequently consulted. 5) The most common dermatoses were eczema group, followed by drug eruption, fungal infection, viral infection, acne vulgaris, urticaria, etc. 6) Distribution of dermatoses according to seasons and individual departments was statistically different in various dermatoses. 7) Frequent causes of consultation were as follows : the dermatologic diseases or conditions 68.3%, the diseases related to treatment 12.3%, the skin lesions of systemic diseases 10.0%, the dermatologic tests 3.5%, and admission to other departments with dermatologic diseases 1.9%, respectively. 8) The rate of consultation for drug eruption was increased markedly compared to that of new patients at OPD in 1998. CONCLUSIONS: The characteristics of inpatient dermatologic consultation in our hospital have been changed and furthermore the characteristics were quite different from that of oupatient practice.
Subject(s)
Female , Humans , Male , Acne Vulgaris , Demography , Diagnosis , Drug Eruptions , Eczema , Incidence , Inpatients , Internal Medicine , Outpatients , Prospective Studies , Seasons , Skin , Skin Diseases , UrticariaABSTRACT
We report a case of AIDS-related Kaposi's sarcoma in a 65-year-old male. He developed many asymptomatic purplish colored patches and nodules on his four extremities and anterior chest with edema of both legs for 2 months. The ELISA for the anti-HIV antibody was positive and it was confirmed by Western blot. The histologic finding showed abnormally proliferated and dilated vessels, vascular slits, spindle-shaped cells and extravasated erythrocytes in the dermis. In immunohistochemical study, the cryptic vessels were positive with CD31. Human herpesvirus-8 was detected by PCR.
Subject(s)
Aged , Humans , Male , Blotting, Western , Dermis , Edema , Enzyme-Linked Immunosorbent Assay , Erythrocytes , Extremities , Leg , Polymerase Chain Reaction , Sarcoma, Kaposi , ThoraxABSTRACT
Ewing's sarcoma is a highly anaplastic, small round cell tumor, primarily arising in the intramedullary portion of the bone, and metastasis is common. Its origin is unknown. We describe a case of cutaneous metastatic Ewing's sarcoma in the pubic area in a 23-year-old female, who had been diagnosed as having Ewing's sarcoma of the pelvic bone three years ago, and treated by wide excision, chemotherapy and radiation therapy. Histopathologic examination of her nodular lesion revealed a tumor of small round cells whose membranes were positive for CD99. She was managed by conservative treatment but expired one month later. To our knowledge, Ewing's sarcoma metastatic to the skin has not been reported previously in the world. This case supports the neuroectodermal origin of this tumor and that cutaneous metastasis of this tumor is a hallmark of grave prognosis.
Subject(s)
Female , Humans , Young Adult , Drug Therapy , Membranes , Neoplasm Metastasis , Neural Plate , Pelvic Bones , Prognosis , Sarcoma, Ewing , SkinABSTRACT
Systemic PUVA therapy can produce various acute reactions and potential long-term damage including benign and malignant skin tumors. Obviously the risk is related to DNA damage, but PUVA-induced down-regulation of immune responses may play an additional role. Keratoacanthoma is etiologically related to sunlight and immunosuppression. PUVA keratoses are raised warty papules with a broad base and a diameter of several millimeters to 1 centimeter, and they are associated with an increased risk of nonmelanoma skin cancer. We report a case of solitary keratoacanthoma and multiple PUVA keratoses all developing in vitiliginous areas in a patient receiving long-term, high-dose PUVA therapy for generalized vitiligo. A 57-year-old Korean female, who had undergone intermittent systemic PUVA therapy for 11 years, noted multiple asymptomatic, yellowish, hyperkeratotic papules on the dorsa of hands and feet 1 year previously, and a bean-sized raised painful nodule filled with keratin plug on the dorsum of right hand 1 month previously. Skin biopsy confirmed the diagnoses of PUVA keratoses and keratoacanthoma, respectively. PCR-SSCP analysis revealed no mutation of p53 tumor suppressor gene in this case.
Subject(s)
Female , Humans , Middle Aged , Biopsy , Diagnosis , DNA Damage , Down-Regulation , Ficusin , Foot , Genes, Tumor Suppressor , Hand , Immunosuppression Therapy , Keratoacanthoma , Keratosis , Photochemotherapy , PUVA Therapy , Skin , Skin Neoplasms , Sunlight , VitiligoABSTRACT
Tufted angioma is a benign, slowly progressive angioma with typical histologic findings of small, circumscribed angiomatous tufts and lobules scattered in the dermis. More than 50% of cases occur during the first year of life, but rarely it develops late in life. There was only one reported case of tufted angioma after trauma in the English literature. We report a case of tufted angioma, which developed after electrocautery in a 61-year-old woman showing histologic features of typical tufted angioma.
Subject(s)
Female , Humans , Middle Aged , Dermis , Electrocoagulation , HemangiomaABSTRACT
Subcorneal pustular dermatosis(SPD) or Sneddon-Wilkinson disease is a chronic, relapsing, pustular eruption generally involving the intertriginous area and affecting mainly elderly women. We report a case of SPD presenting in a 24-year-old female with erythematous circinate annular peripheral scaly patches on her right thigh. Histopathologically, the subcorneal pustules contained numerous neutrophils, with only a few eosinophils. Underlying stratum malpighii was slightly edematous and contained small numbers of neutrophils. No acantholytic cells or spongiosis were found. The patient was treated by dapsone successfully.
Subject(s)
Aged , Female , Humans , Young Adult , Dapsone , Eosinophils , Neutrophils , Skin Diseases, Vesiculobullous , ThighABSTRACT
Trichorrhexis nodosa is the most common hair shaft anomaly in which there is a distinctive response to injury. The hair is fragile and on examination pale `node-like' swelling may be observed. It may affect normal hair following excessive or repeated trauma, or may occur after minimal trauma if there is an inherent defect in keratin synthesis causing abnormally brittle hair. We report a case of localized trichorrhexis nodosa in a 42-year-old male who had scratched frequently for the relief of the pruritus in the parietal area. Scanning electron microscopy revealed longitudinal fissures and fracture in the cortex. A paint brush effect was noted at the site of fracture.
