Performance of glycated haemoglobin (HbA1c) as a screening test for diabetes and impaired glucose tolerance (IGT) in a high risk population--the Brazilian Xavante Indians.

AIMS: To examine the properties of HbA1c to detect diabetes and IGT in adult Brazilian Xavante Indians, a high risk population for diabetes. METHODS: The survey was carried out between October 2010 and January 2012 and based on a 75 g oral glucose tolerance test (OGTT). Basal and 2h capillary glycaemia were measured by HemoCue Glucose 201+; HbA1c using an automated high-performance liquid chromatography analyzer (Tosoh G7). RESULTS: 630 individuals aged ≥ 20 years were examined and 80 had a previous diagnosis of diabetes. Sensitivity, specificity and accuracy for HbA1c ≥ 6.5% (≥ 48 mmol/mol) were 71.3%, 90.5% and 87.2%. The areas under the ROC curve (AUC) was 0.88 (95%CI: 0.83-0.93). To identify IGT, HbA1c values between 5.7% and 6.4% (39-47 mmol/mol) presented sensitivity, specificity and accuracy of 87.2%, 24.7% and 51.4%, with an AUC of 0.62 (95%CI: 0.57-0.67). CONCLUSIONS: The ADA/WHO proposed cut-off of 6.5% (48 mmol/mol) for HbA1c was adequate to detect diabetes among the Xavante. However, the performance of the ADA proposed cut-off points for pre-diabetes, when used to detect IGT was inadequate and should not be recommended.

Effects of different pretreatments on the bond strength of a dual-cure resin core material to various fiber-reinforced composite posts.

The aim of this study was to evaluate the effects of different pretreatments on the bond strength of a dual-cure resin core to 3 types of fiber posts. Bond strength was measured using a push-out design. One-sided t-Test of Hypothesis with unknown variance was performed (p-values < 5%). Sandblasting abrasion with 50 micro alumina particles at a specific distance, pressure and time was the only surface treatment in DT Light Post and Transluma Post that increased the bond strength to dual cure resin composite cores. FRC Postec Plus post did not shown an increase in bond strength in any group.

The relationship between fibre post geometry and flexural properties: an assessment through a modified three-point bending test.

The aim of this study was to investigate the flexural properties of five types of fiber-reinforced dowels using a modified three-point bending test. Fiber-reinforced resin dowels were tested by a modified three-point bending test associated with models for cylindrical and conical simple-supported beams. The fracture load ranged from 86 to 246 N and the flexural strength from 423 to 1192 MPa. FRC Postec had significantly higher flexural strength and fracture loads values. Thus, the present study demonstrated higher flexural strength values for the FRC Postec fibre posts, suggesting that this system would present a better response to the forces of mastication.

Ro 5-3350 (Lexotan) endovenoso como medicacao pre-anestesica. / Intravenous bromazepam as a premedication

Investigou-se, em ensaio aberto, a atuacao do bromazepam (Lexotan Roche) como medicacao pre-anestesica, em 20 pacientes com idade media de 36 anos, de ambos os sexos e peso medio de 64 kg. Os pacientes apresentavam risco cirurgico grau I (55% dos casos) e grau II (45% dos casos). Empregou-se anestesia condutiva para melhor observacao do efeito ansiolitico e sedativo do bromazepam. Os resultados concordam com a literatura mundial no que se refere a boa tolerabilidade cardiorespiratoria e ao efeito ansiolitico apreciavel (80% dos pacientes apresentavam-se tranquilos e cooperativos) do bromazepam, que se revelou seguro em pacientes idosos. Todos os pacientes referiram sensacao de bem-estar e ausencia de recordacoes desagradaveis