[Differentiation and cytogenesis of endocrine elements of the rat duodenum in ontogenesis]. / Differentsirovka i tsitogenez éndokrinnykh élementov dvenadtsatiperstnoi kishki krysy v ontogeneze.

Duodenal endocrine apparatus was studied in rat during individual development using electron microscopy. Endocrinocyte differentiation was demonstrated to occur in embryonic period and it is characterised by fast cytotype number growth. During embryogenesis processes of endocrinocyte differentiation occur more intensely than in adult animals which is manifested by higher incidence of different types of incretory elements in embryos. By the moment of birth EC-, L-, S-, D-, D1-, P and I-cells can be identified in the duodenal epithelium at different stages of differentiation as well as "mixed" exo-endocrine cells. The presence of transitory cellular forms from agranular elements up to mature differentiated endocrinocytes and "mixed" exo-endocrine cells reflects cytogenetic processes in population of endocrine cells and allows to consider duodenal epithelium both structurally and functionally as a tissue with common histogenetic basis.

[The morphofunctional changes in the EC cells of the duodenum in the white rat during starvation]. / Morfofunktsional'nye izmeneniia EC-kletok dvenadtsatiperstnoi kishki beloi krysy pri golodanii.

EC-cells morphofunctional changes were studied in the albino rats duodenal mucosa in different periods of starvation (1, 2, 3, 6 days). Dynamics of the endocrinocyte number increase and change of argentaffine reaction extent indicate active participation of duodenal EC cells in the development of compensatory-adaptive reactions induced by starvation.