The Dermal Ridges as the Infallible Signature of Skin: An Overview.

Our skin is the largest organ and is composed of the dermis and epidermis. The skin surface has lines in the direction of elastic tension. The palmar and plantar skin lines are established before birth in the intrauterine development of the embryo. Dermatoglyphics is the study of epidermal lines on the palmar and plantar surface. It is a branch of biology, anthropology, genetics, and dermatology. Dermatoglyphics are closely associated with genetic factors. These attributes once formed in the womb remain unique and persist throughout the life of an individual unless the dermis is damaged. Digital and palmar dermatoglyphics are represented by fingerprint patterns, atd angle, a, b, c, d triradii, mail line index, etc. Sometimes either due to hereditary reasons, the pressure of intrauterine factors, or external environmental factors, chromosomal aberrations occur in the fetus. These aberrations are reflected in the form of increased angle of atd, variation in pattern frequency or ridge count between a-b triradii (ABRC), presence of unnatural flexion creases, and others in the fingerprints, palmprints, or footprints. These aberrations in dermatoglyphics are useful in studying the genetic abnormalities in ailments, personality disorders, and criminal tendencies.

Neuroinvasive West Nile Virus Post-Heart Transplantation: A Case Report.

First described in the United States in the late 1990s, West Nile virus (WNV) infection following solid organ transplantation is a rare but life-threatening complication. The many ways in which WNV may be acquired, patient specific risk factors, and variability in clinical severity present challenges to health care providers caring for these patients.

Dynamics of latent fingerprints: the effect of physical factors on quality of ninhydrin developed prints--a preliminary study.

The conditions under which latent fingerprints are deposited affect the process of development that can be used to effectively recover these marks. The conditions which can play a part include environmental conditions, the type of surface on which latents are deposited, the ability of the donor to deposit fingerprints, contact time, force of contact with the object etc. Very little previous work is available in the scientific literature addressing these conditions and therefore, an attempt has been made in this present study to assess the effect of some of these criteria and their effect on the ability of ninhydrin to develop the marks. Latent fingerprints from good and bad donors were obtained on paper with variable pressure under controlled conditions. Laboratory prepared 1% ninhydrin solution was used to visualise the prints.

Small particle reagents: development of fluorescent variants.

Small particle reagent (SPR) is a widely used method to develop latent fingerprints on non-porous and wet surfaces. Conventionally, molybdenum disulfide based SPR has been used for the development of latent fingerprints while some SPR based on other materials such as charcoal powder, zinc carbonate and titanium dioxide have been reported. Fluorescent preparations of molybdenum disulfide based SPR have also been reported. In the present work, a number of SPR based on zinc carbonate have been developed in combination with various fluorescent dyes to develop latent fingerprints on a number of non-porous surfaces. The quality of the developed fingerprints have been evaluated and found to be reproducible. The shelf life of the reagents developed is found to be acceptable for case work purposes. The relationship between the immersion period of the substrate bearing the latent fingerprints and reagent has also been examined.

Development of latent fingerprints on compact disc and its effect on subsequent data recovery.

Chance fingerprints may be found on every type of surfaces of contact and when they are latent, need to be developed by various methods. The type of surface on which latent prints are to be developed is one of the important factors when a choice for a method of development is to be made. The matter becomes more crucial when the surface is unique like a compact disc containing digital data. In this case, to develop the fingerprints is not the only matter to be taken care of but also, is very important to select such a method which may not effect the stored data and its retrieval. In present investigation, various methods have been tried to develop fingerprints on the writing surface of a CD and results are discussed with respect to their development as well as its effect on stored data and data retrieval.

Powder method for detecting latent fingerprints: a review.

The powder technique for detecting latent fingerprints involves the application of a finely divided formulation to the fingermark impression, generally with a glass-fibre or a camel hair brush. The powder gets mechanically adhered to the sweat residue defining the ridge pattern. The furrows which are devoid of the fingerprint residue, do not adhere the powder onto them. The final outcome is that the powder formulation sticks to the ridges, but is easily blown off the furrows. Since the powder is normally coloured, the ridge pattern becomes visible and the latent print is said to have developed.

Fingermarks detection by eosin-blue dye.

Eosin-blue (I) dye, along with a phase transfer catalyst, has been used to detect latent fingerprints on a wide range of surfaces, including paper, glass, steel, lamination sheets, polythene, plastic and bakelite.

Structure Determination and Anti-Inflammatory Activity of some Purine Complexes.

Organomercury(II)-purine derivatives of the type, p-MeOC(6)H(4)HgL(1) (I), p-NO(2)C(6)H(4)HgCl(L(2))(II), p-MeC(6)H(4)HgCl(L(3))(III) and p-NO(2)C(6)H(4)HgCl(L(3))(IV) [ HL(1) = theophylline, L(2) = theobromine, L(3) = caffeine] have been synthesised and characterised on the basis of spectral studies (IR, UV, (1)H & (13)C NMR). The complexes have been screened for anti-inflammatory activity.

Organomercury (II) complexes with anti-carcinogenic agents. I. Synthesis and characterization.

A few organomercury (II) complexes involving anti-carcinogenic ligands have been synthesized. The compounds are of the type p-MeOC6H4HgL1 (I), p-NO2C6H4HgL2 (II), p-MeOC4H4HgL3 (III) and p-MeC6H4HgL4 (IV) (HL1-6-mercaptopurine, HL2-6-thioguanine, HL3-5-fluorouracil, L4-phenyldithiocarbazate). Their composition has been determined from elemental analysis. Thin layer chromatography (TLC) studies demonstrate that the compounds are pure. Conductance measurement reveal that these derivatives are non-electrolytes. From IR and UV spectral studies the bonding modes of the ligands to the mercury (II) ion have been elucidated. The stoichiometry of the compounds has been confirmed on the basis of 1H and 13C NMR spectra. Some preliminary results of anti-neoplastic activity are reported.

Organomercury (II) complexes with anti-carcinogenic agents. II. Anti-neoplastic activity.

Organomercury(II) complexes of the type, p-MeOC6H4HgL1 (I), p-NO2C6H4HgL2 (II), p-MeOC6H4HgL3 (III) and p-MeC6H4HgL4 (IV) (HL1-6-mercaptopurine, HL2-6-thioguanine, HL3-5-fluorouracil, L4-phenyldithiocarbazate) have been screened against the following cell panels: leukemia, non-small cell lung cancer, small cell lung cancer, brain cancer, melanoma, ovarian cancer and renal cancer. The variation in anti-neoplastic activity has been correlated with the structural parameters of the complexes.

Organomercury(II) complexes of kojic acid and maltol: synthesis, characterization, and biological studies.

A number of organomercury(II) complexes of kojic acid (HL1, I) and maltol (HL2, II) of the type p-XC6H4HgL1 (III) and p-XC6H4HgL2 (IV) [X = Me, MeO, NO2] have been synthesized and characterized. [formula: see text] Conductance measurements indicate the nonelectrolyte behavior of the complexes. From IR and UV studies, the bonding modes of the ligands to the organomercury(II) moieties have been elucidated. The 1H and 13C NMR spectra support the stoichiometry of the complexes. The fragmentation pattern has been analyzed on the basis of mass spectra. From thermal studies (TG and DTA), various kinetic and thermodynamic parameters for thermal degradation have been enumerated. The complexes have been screened against some pathogenic bacterial strains. The bactericidal activity has been correlated with the thermal data.

Diuretic activity of organomercury (II) complexes of theophylline and theobromine.

Organomercury(II) complexes of the types, p-XC6H4HgL (A) and p-XC6H4HgCl(L') (B) [LH = theophylline; L' = theobromine; X = Me, NO2], have been synthesised and characterized. Conductance measurements indicate that the complexes are non-electrolytes. The structures of the complexes have been elucidated by spectral studies (IR, UV, and 1H, 13C NMR). The complexes have been tested for diuretic activity. The structure-activity relationship has been propounded.

Organomercury(II) complexes of 6-thioguanine: synthesis, characterization, and biological studies.

Organomercury(II) complexes involving 6-thioguanine, of the type p-XC6H4HgL (Fig. 1) [LH = 6-thioguanine; X = Me, MeO, NO2], have been synthesized and characterized. Conductance measurements indicate that the complexes are nonelectrolytes. From IR and UV studies, it is concluded that 6-thioguanine acts as a bidentate ligand, coordinating through the 6-thione group and deprotonation of N-7. 1H and 13C NMR support the stoichiometry of the complexes. From thermal studies (TG and DSC) various kinetic and thermodynamic parameters for thermal degradation have been enumerated. In addition, the fragmentation pattern of the complexes have been analyzed on the basis of mass spectra. The p-MeC6H4HgL and p-MeOC6H4HgL complexes display significant activity against L1210 leukemia cells.

Studies on organomercury(II) complexes of isoniazid.

A number of organomercury(II) complexes involving isoniazid (I), of the type RHgCl(L)(II) [R = phenyl(C6H5), o-hydroxyphenyl (o-HOC6H4), p-hydroxyphenyl (p-HOC6H4), p-acetoxyphenyl (p-AcOC6H4), 2-furyl (2-C4H3O); L = isoniazid] have been synthesized and characterized. Conductance measurements indicate that the complexes are nonelectrolytes. From IR and UV studies, it is concluded that isoniazid acts as a bidentate ligand, coordinating through hydrazinic nitrogen and carbonyl oxygen. 1H and 13C NMR support the stoichiometry of the complexes. From fluoroscence studies a number of photochemical parameters have been elucidated. For the C6H5HgCl(L), p-HOC6H4HgCl(L), and p-AcOC6H4HgCl(L) complexes, thermogravimetric studies have been carried out and relevant kinetic and thermodynamic parameters for thermal degradation have been enumerated. In addition, the fragmentation pattern of the complexes has been analyzed on the basis of mass spectra. The C6H5HgCl(L) and p-HOC6H4HgCl(L) complexes have been screened for tuberculosis activity.