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1.
Vrach Delo ; (2): 107-9, 1989 Feb.
Article in Russian | MEDLINE | ID: mdl-2711647

ABSTRACT

A study is presented of indices of unspecific resistance of the body in 63 patients with erysipelas during the acute period of the disease and during recovery. In the acute period of the disease all patients revealed depending on the degree of endogenous intoxication: reduction of the content of fibronectin in the blood, significant reduction of the resistance of erythrocytes--increase of the per cent of peroxidation hemolysis, increase of the content of malonic dialdehyde--an index of disorders of lipid peroxidation, increased content middlemolecular peptides, circulating immune complexes and products of fibrin-fibrinogen degradation. The authors substantiate the expediency of using sodium thiosulfate possessing detoxicating, antiinflammatory and antiallergic antioxidant properties and the capacity to bind circulating immune complexes.


Subject(s)
Erysipelas/immunology , Adolescent , Adult , Antigen-Antibody Complex/analysis , Antioxidants , Erysipelas/blood , Erysipelas/drug therapy , Humans , Immunity, Innate , Lipid Peroxidation , Middle Aged , Thiosulfates/therapeutic use
4.
Vopr Med Khim ; 26(4): 548-52, 1980.
Article in Russian | MEDLINE | ID: mdl-7456399

ABSTRACT

Gas chromatography of total lipids from blood serum exhibits about 40% error in diagnosis of liver functional insufficiency. Combination of gas chromatography with quantitative thin-layer chromatography and subsequent gas chromatographic analysis of the lipid fractions obtained enabled to increase by 25% the efficiency of diagnoses not only of icteric but also of non-icteric forms of liver functional insufficiency. Simultaneous gas- thin-layer chromatographic analysis of total lipids will apparently improve the differential diagnosis of diseases accompanied by liver functional insufficiency; it permits also to study pathogenesis of impairments in lipid metabolism under conditions of liver functional insufficiency and of other pathologies.


Subject(s)
Lipids/blood , Liver Diseases/blood , Adolescent , Adult , Chromatography, Gas , Chromatography, Thin Layer , Diagnosis, Differential , Humans , Middle Aged
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