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2.
Zh Mikrobiol Epidemiol Immunobiol ; (9): 49-54, 1985 Sep.
Article in Russian | MEDLINE | ID: mdl-4072497

ABSTRACT

The results of the clinico-laboratory and epidemiological study of a newly developed live measles vaccine obtained from strain Moscow-5, genetically homogeneous and cloned from strain JI-16, are presented. The data indicate that the vaccine obtained from strain Moscow-5 is safe and possesses low reactogenicity and high immunological potency, thus meeting all requirements for vaccinal preparations.


Subject(s)
Antibodies, Viral/analysis , Measles Vaccine/immunology , Measles virus/immunology , Measles/immunology , Adolescent , Animals , Child , Child, Preschool , Coturnix , Embryo, Nonmammalian , Female , Follow-Up Studies , Humans , Infant , Measles/prevention & control , Serology/methods , Time Factors
9.
Zh Mikrobiol Epidemiol Immunobiol ; (5): 105-9, 1977 May.
Article in Russian | MEDLINE | ID: mdl-197750

ABSTRACT

As a result of observations carried out on children the authors present immunological characteristics of two-stage smallpox vaccination at different intervals (1 to 60 days) between the injection of inactivated and live vaccine. There proved to be acceleration and intensification of antibody formation after two-stage immunization in comparison with the rutine vaccination. A seven-day interval between the injection of the inactivated and live preparations was recommended on the basis of the data obtained.


Subject(s)
Smallpox Vaccine/administration & dosage , Smallpox/immunology , Antibodies, Viral/isolation & purification , Antibody Formation , Child, Preschool , Evaluation Studies as Topic , Humans , Smallpox Vaccine/therapeutic use , Vaccination/methods , Variola virus/immunology
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