ABSTRACT
VC, FVC, FEV1/VC%, PEF, MEF25, MEF50, MEF75 were studied in 254 patients with lung diseases with bronchial obstruction before and after berotec and antrovent inhalation. Bronchospasm was detected in most patients with bronchial asthma, in a half with exogenous allergic alveolitis, in more than a third with chronic bronchitis and pulmonary tuberculosis, and in a fifth with pulmonary sarcoidosis. In most examinees with bronchospasm, the proportion of the latter in bronchial obstruction amounted to 61-100%.
Subject(s)
Bronchial Spasm/diagnosis , Lung Diseases/physiopathology , Adolescent , Adult , Aged , Alveolitis, Extrinsic Allergic/physiopathology , Asthma/physiopathology , Bronchi/physiopathology , Bronchial Spasm/physiopathology , Bronchitis/physiopathology , Chronic Disease , Female , Humans , Male , Middle Aged , Models, Theoretical , Sarcoidosis, Pulmonary/physiopathology , Tuberculosis, Pulmonary/physiopathologyABSTRACT
The examination of 90 patients suffering from pulmonary tuberculosis with bronchial obstruction (BO) has found bronchospasm in one third of the examinees. In spite of the spasm weakness, its contribution to development of BO is significant: 21-40, 41-80, 81-100% in 4, 6 and 27% of patients.
Subject(s)
Airway Obstruction/etiology , Bronchial Spasm/complications , Tuberculosis, Pulmonary/complications , Airway Obstruction/diagnosis , Airway Obstruction/physiopathology , Bronchial Spasm/diagnosis , Bronchial Spasm/physiopathology , Bronchodilator Agents , Diagnosis, Differential , Follow-Up Studies , Humans , Respiratory Function Tests , Retrospective Studies , Severity of Illness Index , Tuberculosis, Pulmonary/physiopathologyABSTRACT
The results of the clinico-roentgenologic and functional examination of 434 patients with different forms of pulmonary tuberculosis were subjected to analysis. The obstructive syndrome of ventilation disorders was detected in more than 60% of pulmonary tuberculosis patients. The prevalent significance in its pathogenesis was played by disorders of patency of fine bronchi and air distribution in the lungs. They were associated with extension and activity of the processes and their tendency to acquire a chronic form and with the action of nonspecific factors on the bronchi, which included smoking, work under dust-contaminated conditions, concurrent nonspecific pulmonary diseases, nonspecific changes of the principal bronchi revealed by bronchoscopy and structural nonspecific changes of the peripheral air ways detected by a morphologic study of the resected material. A bronchospastic component was responsible for the broncho-obstructive syndrome in 57% of the patients.
