[Resistance of hospital Staphylococci to beta-lactam antibiotics]. / Rezistentnost' gospital'nykh stafilokokkov k betalaktamnym antibiotikam.

Resistance of hospital Staphylococci to beta-lactam antibiotics was studied. The strains were isolated in two obstetric hospitals during an outbreak of purulent inflammatory infections in them. A modification of the "clover leaf" procedure providing elucidation of the resistance mechanism was used in the study. Development of the resistance to the beta-lactam antibiotics was shown to be mainly due the activity of beta-lactamases which makes it possible to discuss their role in the mechanism of resistance development.

[Methods of determination of toxicity of pertussis vaccine. 1. Change in the weight of the thymus gland and the spleen in mice after administration of pertussis vaccine]. / K voprosu o metodakh opredeleniia toksichnosti kokliushnykh vaktsin. Soobshchenie 1. Izmenenie vesa timusa i selezenki u myshei posle vvedeniia kokliushnoi vaktsiny.

Experiments were conducted on mice, strain NIH, line HSFS/N, immunized with pertussis vaccine. Determination of thymocyte pool proved to be a more sensitive method of detection of the stress effect of the vaccine than determination of the thymus weight. The test can be used for the elaboration of the method of assessment of the toxicity of pertussis preparations.