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1.
Fiziol Cheloveka ; 36(6): 32-40, 2010.
Article in Russian | MEDLINE | ID: mdl-21254604

ABSTRACT

At 8 healthy examinees-volunteers of 22-25 years the functional effects of super-threshold (above 1.2 T) and subthreshold (70-80% of a motor threshold) rTMS of premotor cortexes medial departments were compared. Functional brain activity changes were estimated (before and 1 hour after stimulation) by comparing data including neuropsychological testing, visual and spectral-coherent EEG-analysis, and also haemodynamic parameters. The number of the work's problem included selection of activating orientated stimulation's frequency, and also specification objective EEG--criteria of efficiency rTMS. It is established the effect of EEG-analysis during different frequency photostimulation for a choice of activating rTMS. The received results reveal EEG-coherence as one of the most informative characteristics of cerebral neuro-dynamics under rTMS-influence. Dependence of stimulation's functional effects (activated or brake character) from initial level of the intercentral coherent communications is noted. It is revealed that rTMS of the healthy examinees causes certain changes of functional activity of a brain, distinct from placebo-effects. rTMS-effect dependent on intensity (super--or sub-threshold), and also from features of an initial intercentral rations. More expressed functional changes are observed in the left hemisphere. It is shown big by reactance of the left hemisphere on this influence. In formation of brain responses on rTMS the active role of the vascular factor is shown.


Subject(s)
Brain Waves/physiology , Cerebrum/physiology , Transcranial Magnetic Stimulation/methods , Adult , Humans , Male
2.
Article in Russian | MEDLINE | ID: mdl-2173303

ABSTRACT

Complex study of the effect of sodium nitroprusside intra-arterial and intravenous infusion under local and general anesthesia on the cerebral, peripheral, and general hemodynamics during cerebral angiography was carried out in 43 patients with neurosurgical pathology (17 females and 26 males from 17 to 58 years of age). The authors proved the efficacy of intraarterial and, to a lesser measure, of intravenous sodium nitroprusside infusion in relieving spasm of the cerebral arteries developing during cerebral angiography.


Subject(s)
Anesthesia, Local/methods , Cerebral Angiography/methods , Nitroprusside/therapeutic use , Adolescent , Adult , Brain Neoplasms/diagnostic imaging , Cerebral Arteries/drug effects , Cerebrovascular Disorders/diagnostic imaging , Cerebrovascular Disorders/prevention & control , Drug Evaluation , Female , Humans , Male , Middle Aged , Spasm/prevention & control
4.
Article in Russian | MEDLINE | ID: mdl-4002954

ABSTRACT

Specific features of motor activity disorders were studied in 87 patients before and after removal of a parasagittal meningioma. Motor disorders are most severe in localization of the tumor in the region of the middle third of the superior sagittal sinus and falx and less severe when the tumor is found in the posterior parts of the anterior third of the superior sagittal sinus. The disorders are more marked after operation with extensive resection of areas of the superior sagittal sinus involves in the tumor and with occlusion of the formed venous drainage passages. The motor disorders are particularly severe after removal of parasagittal meningiomas and are often bilateral with multiple components (including disturbances in the pyramidal and extrapyramidal systems, afferent regulation of movements, and coordinated work of both hemispheres in the formation of motor acts). Not only the direct effect of the pathological focus on the cerebral motor zones situated at different levels but disorders of cerebral and peripheral circulation are of importance in the pathogenesis of these disturbances.


Subject(s)
Brain Neoplasms/surgery , Meningeal Neoplasms/surgery , Meningioma/surgery , Paralysis/etiology , Adult , Aged , Cerebrovascular Circulation , Electroencephalography , Female , Humans , Male , Middle Aged , Paralysis/physiopathology , Plethysmography, Impedance , Postoperative Complications/etiology , Postoperative Complications/physiopathology
5.
Article in Russian | MEDLINE | ID: mdl-860625

ABSTRACT

The data of electromyographic studies of the bioelectrical activity of the facial muscles following plastic repair of the facial nerve with the aid of the descending branch of the hypoglossal nerve permit to interpret the succession and quality of the reinnervation of the muscles. Myoelectrogenesis, as shown by the examinations of 13 patients, develops earlier and with greater completeness in the muscles around the mouth than in the orbicular eye muscle and the frontal muscle, which corresponds to the clinical observations. In the process of reinnervation the activity of the zygomaticus muscle favoured the formation of joint and voluntary movements of the orbicular muscle of the eye and of the frontal muscle.


Subject(s)
Facial Nerve/surgery , Facial Paralysis/surgery , Hypoglossal Nerve/surgery , Electromyography , Facial Paralysis/diagnosis , Follow-Up Studies , Humans
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