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1.
Hydroxynybomycin: isolation, structure and bioactivity.
Nadzan, A M; Rinehart, K L; Sokolski, W T.
J Antibiot (Tokyo) ; 30(6): 523-4, 1977 Jun.
Article in English | MEDLINE | ID: mdl-885812

Subject(s)
Anti-Bacterial Agents/isolation & purification , Anti-Bacterial Agents/pharmacology , Bacteria/drug effects , Chemical Phenomena , Chemistry , Magnetic Resonance Spectroscopy , Mass Spectrometry , Spectrophotometry, Infrared
2.
Microbial formation of 4-thiouracil.
Dolak, L; Sokolski, W T; Mizsak, S; Stroman, D W; Sebek, O K.
Antimicrob Agents Chemother ; 11(3): 569-70, 1977 Mar.
Article in English | MEDLINE | ID: mdl-404965

ABSTRACT

A soil organism identified as Streptomyces libani var. soldani was found to produce 4-thiouracil. The product was isolated in a yield of 150 mug/ml of filtered beer and characterized by C-13 magnetic resonance and high-resolution mass spectroscopy. The product has a broad antibacterial spectrum but low specific activity.


Subject(s)
Streptomyces/metabolism , Thiouracil/biosynthesis , Bacillus subtilis/drug effects , Fermentation , Microbial Sensitivity Tests , Thiouracil/pharmacology
3.
The effect of freezing and thawing on cellular function in Lactobacillus leichmannii.
Stapert, E M; Sokolski, W T.
Cryobiology ; 4(4): 174-6, 1968.
Article in English | MEDLINE | ID: mdl-5746211

Subject(s)
Freezing , Lactobacillus/metabolism , Lactobacillus/growth & development , Vitamin B 12/metabolism
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