ABSTRACT
Mycobacterium lentiflavum infrecuentemente provoca patogenicidad en el ser humano, aunque se ha descrito como causante de linfadenitis cervical y afectación pulmonar. Generalmente presenta un curso clínico poco agresivo y se asocia un patrón radiológico nódulo-bronquiectásico. En nuestro caso relatamos un paciente con clínica respiratoria inespecífica y presencia de bronquiectasias y lesiones de morfología pseudonodular en la tomografía computarizada (TC) torácica. En la TC torácica de control y tomografía por emisión de positrones (PET) se evidenció aumento de tamaño y del metabolismo de dichas lesiones. Se realiza biopsia para descartar malignidad creciendo en cultivo de la muestra Mycobacterium lentiflavum
Mycobacterium lentiflavum infrequently causes pathogenicity in humans, although it has been identified as causing cervical lymphadenitis and lung involvement. It usually has a poorly aggressive clinical course and a nodule-bronchiectatic radiological pattern is associated. In our case, we report a patient with a nonspecific respiratory clinic and presence of bronchiectasis and pseudonodular morphology lesions in thoracic computed tomography. In the thoracic CT scan of positron emission tomography (PET) there was evidence of an increase in the size and metabolism of these lesions. Biopsy is performed to rule out malignancy, with Mycobacterium lentiflavum growing in sample culture
Subject(s)
Humans , Male , Middle Aged , Mycobacterium/isolation & purification , Mycobacterium Infections/microbiology , Pneumonia, Bacterial/microbiology , Bronchiectasis/microbiology , Mycobacterium Infections/diagnostic imaging , Pneumonia, Bacterial/diagnostic imaging , Tomography, X-Ray Computed , Bronchiectasis/diagnostic imaging , Positron-Emission TomographyABSTRACT
En un informe rutinario dermatopatológico sobre un melanoma se recoge una significativa información pronóstica para el manejo de estos pacientes y que actualmente es empleada en la estadificación de la American Joint Committee on Cancer como el grosor tumoral, la presencia de ulceración, el número de mitosis y la presencia o no de microsatelitosis. Sin embargo, existen múltiples factores que si bien no están incluidos en esta clasificación, han demostrado tener un impacto pronóstico en diversos estudios y que son objeto del presente texto (AU)
Skin histopathology reports of melanoma routinely include important prognostic information used in the staging system of the American Joint Committee on Cancer (AJCC).This information, which influences disease management, includes tumor depth, presence of ulceration, number of mitotic figures, and presence or absence of microsatellites. However, numerous studies have found many other factors that are not included in the AJCC classification but that are nevertheless of prognostic significance. We discuss these factors in this paper (AU)
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Skin Diseases/diagnosis , Skin Diseases/epidemiology , Skin Diseases/pathology , Histology/education , Skin Diseases/etiology , Skin Diseases/microbiology , Skin Diseases , Histology/statistics & numerical data , Histology/trends , Neoplasm Staging/methods , Neoplasm Staging/statistics & numerical data , Neoplasm Staging , Mitotic Index/methods , Mitotic Index/statistics & numerical dataABSTRACT
Skin histopathology reports of melanoma routinely include important prognostic information used in the staging system of the American Joint Committee on Cancer (AJCC). This information, which influences disease management, includes tumor depth, presence of ulceration, number of mitotic figures, and presence or absence of microsatellites. However, numerous studies have found many other factors that are not included in the AJCC classification but that are nevertheless of prognostic significance. We discuss these factors in this paper.
Subject(s)
Melanoma/mortality , Skin Neoplasms/mortality , Age Factors , Disease Progression , Female , Humans , Inflammation , Lymphatic Metastasis , Male , Medical Oncology , Melanoma/classification , Melanoma/pathology , Neoplasm Regression, Spontaneous , Neoplasm Staging/methods , Neoplasm Staging/standards , Organ Specificity , Prognosis , Risk Factors , Sex Factors , Skin Neoplasms/classification , Skin Neoplasms/pathology , Societies, Medical , United StatesABSTRACT
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Subject(s)
Humans , Male , Aged , Lichen Planus/diagnosis , Tacrolimus/therapeutic use , Diagnosis, DifferentialSubject(s)
Keratosis/pathology , Precancerous Conditions/pathology , Aged , Humans , Keratosis/surgery , Male , Precancerous Conditions/surgery , SternumABSTRACT
We present a case of lymphoepithelioma of the larynx, a very rare tumour in this location. The relationship between lymphoepithelial carcinoma of the larynx and Epstein-Barr virus, is still controversial. We describe one new case of this tumour involving the supraglottis, and it's surgery and radioterapic treatment. The diagnostic problems and therapy associated with this rare tumour are discussed.
Subject(s)
Carcinoma, Squamous Cell/diagnostic imaging , Laryngeal Neoplasms/diagnostic imaging , Aged , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/surgery , Humans , Laryngeal Neoplasms/pathology , Laryngeal Neoplasms/surgery , Male , Tomography, X-Ray ComputedABSTRACT
Presentamos un caso de linfoepitelioma de laringe, un raro tumor en esta localización. La relación entre este tumor y el virus Epstein-Barr, establecida en otras localizaciones, es en esta muy discutida. Describimos un nuevo caso de este tumor, de origen supraglótico, junto a su tratamiento quirúrgico y radioterápico, así como los problemas de diagnóstico que plantea esta rara entidad (AU)
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Subject(s)
Male , Humans , Aged , Tomography, X-Ray Computed , Carcinoma, Squamous Cell , Laryngeal NeoplasmsABSTRACT
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Subject(s)
Adult , Female , Humans , Hyperkeratosis, Epidermolytic/diagnosis , Hyperkeratosis, Epidermolytic/etiology , Hyperkeratosis, Epidermolytic/pathology , Hyperkeratosis, Epidermolytic/therapy , Nevus, Pigmented/diagnosis , Nevus, Pigmented/etiology , Nevus, Pigmented/pathology , Nevus, Pigmented/complications , Keratins/analysis , Hair Diseases/complications , Hair Diseases/diagnosis , Hair Diseases/pathology , Skin Neoplasms/complications , Skin Neoplasms/diagnosis , Skin Neoplasms/pathology , Skin/pathology , Skin/cytology , Skin Diseases/complications , Skin Diseases/diagnosis , Skin Diseases/pathologyABSTRACT
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Subject(s)
Female , Middle Aged , Humans , Folliculitis/surgery , Folliculitis/diagnosis , Folliculitis/physiopathology , Histological Techniques , Epidermal Cyst/surgery , Epidermal Cyst/diagnosis , Epidermal Cyst/etiology , Vulvar Diseases/surgery , Vulvar Diseases/diagnosis , Vulvar Diseases/etiology , Vulvar Neoplasms/diagnosis , Vulvar Neoplasms/etiology , Vulvar Neoplasms/pathology , Diabetes Mellitus, Type 2/diagnosis , Diabetes Mellitus, Type 2/complications , Diabetes Mellitus, Type 2/pathology , Diabetes Mellitus, Type 2/drug therapy , Sebaceous Gland Neoplasms/diagnosis , Sebaceous Gland Neoplasms/pathology , Sebaceous Gland Neoplasms/ultrastructure , Sebaceous Gland Neoplasms/genetics , Vulva/pathology , Histocytological Preparation Techniques , Hypoglycemic Agents/therapeutic useABSTRACT
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Subject(s)
Aged , Male , Humans , Carcinoma, Basal Cell/surgery , Carcinoma, Basal Cell/diagnosis , Carcinoma, Basal Cell/etiology , Carcinoma, Basal Cell/pathology , Scalp/anatomy & histology , Scalp/pathology , Scalp Dermatoses/diagnosis , Scalp Dermatoses/pathology , Scalp Dermatoses/therapy , Keratosis, Seborrheic/diagnosis , Keratosis, Seborrheic/etiology , Keratosis, Seborrheic/pathology , Histological Techniques , Histology, Comparative/methods , Skin Neoplasms/diagnosis , Skin Neoplasms/immunology , Skin Neoplasms/pathology , Histocytological Preparation Techniques , Skin/pathology , Skin/ultrastructure , Skin/anatomy & histologyABSTRACT
El carcinoma basocelular de células granulares es un subtipo de carcinoma basocelular caracterizado por la presencia de células neoplásicas con hallazgos citológicos de células granulares, que forman parte o constituyen la totalidad de la tumoración. Es una variante rara, y el caso que presentamos es el octavo descrito en la literatura mundial. Los estudios inmunohistoquímico y ultraestructural demuestran que las células granulares proliferantes son de origen epitelial (AU)
Subject(s)
Male , Middle Aged , Humans , Carcinoma, Basal Cell/diagnosis , Carcinoma, Basal Cell/etiology , Carcinoma, Basal Cell/pathology , Immunohistochemistry/methods , Microscopy/methods , Carcinoma , Lysosomes/pathology , Phagosomes/pathology , Granular Cell Tumor/diagnosis , Granular Cell Tumor/pathology , Neoplasms, Glandular and Epithelial/diagnosis , Neoplasms, Glandular and Epithelial/pathology , Desmosomes/pathology , Neoplasms, Muscle Tissue/pathology , Neoplasms, Muscle Tissue/diagnosis , Keratins/analysis , Keratins , Stromal Cells/cytology , Stromal Cells/pathologyABSTRACT
A relation between kidney and inner ear disease, specifically neurosensorial hearing loss, has been established. Likewise, the role of tonsillitis in certain glomerulonephritides is well known. A case of post-streptococcal mesangial glomerulonephritis with IgA deposit (Berger's disease) and neurosensorial hearing loss is reported. The absence of any relevant family or personal history suggests an immunological origin for both disorders.
Subject(s)
Glomerulonephritis, IGA/complications , Glomerulonephritis, IGA/immunology , Hearing Disorders/etiology , Adult , Audiometry, Pure-Tone , Female , Glomerulonephritis, IGA/pathology , Hearing Disorders/diagnosis , Humans , Kidney/pathology , Streptococcus/pathogenicity , Tonsillitis/etiologyABSTRACT
Granular cell tumor is a neoplasm usually benign, which only in two percent of the cases affects the esophagus. Histologically it is composed by two kind of cells: granular and angled body cells. The histogenesis of this tumor remains controversial; however, it has been recently demonstrated, by immunohistochemical methods, the presence of proteins that are specific of the nervous system. The diagnosis is frequently done incidentally and by endoscopic biopsy. We report a case of granular cell tumor of the distal esophagus found incidentally during a routine endoscopic examination. We review the English and Spanish literatures, focussing on the histological and diagnostic peculiarities. The clinical management and the different available therapeutics, according to symptoms and tumor size, are discussed.
Subject(s)
Esophageal Neoplasms/pathology , Granular Cell Tumor/pathology , Adult , Humans , MaleABSTRACT
The finding of a double primitive pulmonary neoplasm in the same patient is a fact rarely published, between 0.5 and 3.5% depending on the series, most of them surgical or necropsies series. We present the case of a patient who after being diagnosed of bronchial epidermoid carcinoma and treated with radiotherapy, developed, one year later, a relapsing homolateral pleural effusion due to an oat-cell type carcinoma. We review the incidence of this association in the scientific literature, outlining the difficulty to establish the diagnosis in patients non treated with radical surgery.
