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Rev Med Chir Soc Med Nat Iasi ; 96(3-4): 265-8, 1992.
Article in English | MEDLINE | ID: mdl-1344867

ABSTRACT

New imidazolines derived from sulphonamidated aryloxyalkylcarboxylic acids have been tested for their antihypertensive action and toxicity. The obtained results attest a remarkable biological action, low toxicity and a good absorption in oral administration.


Subject(s)
Antihypertensive Agents/pharmacology , Imidazoles/pharmacology , Morpholines/pharmacology , Animals , Antihypertensive Agents/toxicity , Blood Pressure/drug effects , Cats , Imidazoles/toxicity , Lethal Dose 50 , Mice , Morpholines/toxicity , Structure-Activity Relationship
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