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J Med Vasc ; 45(4): 177-183, 2020 Jul.
Article in English | MEDLINE | ID: mdl-32571557

ABSTRACT

OBJECTIVE: To evaluate the short and long-term results of in situ prosthetic graft treatment using rifampicin-soaked silver polyester graft in patients with aortic infection. MATERIAL AND METHOD: All the patients surgically managed in our center for an aortic infection were retrospectively analyzed. The primary endpoint was the intra-hospital mortality, secondary outcomes were limb salvage, persistent or recurrent infection, prosthetic graft patency, and long-term survival. RESULTS: From January 2004 to December 2015, 18 consecutive patients (12 men and 6 women) were operated on for aortic infection. Six mycotic aneurysms and 12 prosthetic infections, including 8 para-entero-prosthetic fistulas, were treated. In 5 cases, surgery was performed in emergency. During the early postoperative period, we performed one major amputation and two aortic infections were persistent. Intra-hospital mortality was 27.7%. The median follow-up among the 13 surviving patients was 26 months. During follow-up, none of the 13 patients presented reinfection or bypass thrombosis. CONCLUSION: This series shows that in situ revascularization with rifampicin-soaked silver polyester graft for aortic infection have results in agreement with the literature in terms of intra-hospital mortality with a low reinfection rate.


Subject(s)
Aneurysm, Infected/surgery , Anti-Bacterial Agents/administration & dosage , Aortic Aneurysm/surgery , Blood Vessel Prosthesis Implantation/instrumentation , Blood Vessel Prosthesis , Polyesters , Prosthesis-Related Infections/surgery , Rifampin/administration & dosage , Silver , Adolescent , Adult , Aged , Aged, 80 and over , Aneurysm, Infected/diagnostic imaging , Aneurysm, Infected/microbiology , Aneurysm, Infected/mortality , Anti-Bacterial Agents/adverse effects , Aortic Aneurysm/diagnostic imaging , Aortic Aneurysm/microbiology , Aortic Aneurysm/mortality , Blood Vessel Prosthesis/adverse effects , Blood Vessel Prosthesis Implantation/adverse effects , Blood Vessel Prosthesis Implantation/mortality , Female , France , Hospital Mortality , Humans , Male , Middle Aged , Polyesters/adverse effects , Prosthesis Design , Prosthesis-Related Infections/diagnostic imaging , Prosthesis-Related Infections/microbiology , Prosthesis-Related Infections/mortality , Retrospective Studies , Rifampin/adverse effects , Risk Factors , Silver/adverse effects , Time Factors , Treatment Outcome , Young Adult
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