Subject(s)
Eugenol , Oils, Volatile , Phytotherapy , Plant Extracts , Syzygium/chemistry , Animals , Eugenol/adverse effects , Eugenol/pharmacology , Eugenol/therapeutic use , Facial Pain/drug therapy , Fever/drug therapy , Humans , Insect Repellents , Oils, Volatile/adverse effects , Oils, Volatile/pharmacology , Oils, Volatile/therapeutic use , Plant Extracts/adverse effects , Plant Extracts/pharmacology , Plant Extracts/therapeutic use , Premature Ejaculation/drug therapyABSTRACT
An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology and dosing.
Subject(s)
Evidence-Based Medicine , Phytotherapy , Plant Extracts/therapeutic use , Trigonella , Clinical Trials as Topic , Dose-Response Relationship, Drug , Drug Interactions , Humans , Plant Extracts/adverse effects , Plant Extracts/pharmacokinetics , Plant Extracts/pharmacologyABSTRACT
An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.
Subject(s)
Aloe , Evidence-Based Medicine , Medicine, Traditional , Phytotherapy , Plant Extracts/therapeutic use , Clinical Trials as Topic , Dose-Response Relationship, Drug , Drug Interactions , Humans , Plant Extracts/adverse effects , Plant Extracts/pharmacokinetics , Plant Extracts/pharmacology , Research DesignABSTRACT
This systematic review discusses the proposed uses, dosing parameters, adverse effects, toxicology, interactions and mechanism of action of kava. The widespread concern regarding the potential hepatotoxicity of kava is discussed. A recommendation is made to consolidate and analyse available reports and to continue postmarket surveillance in an international repository to prevent duplicates and promote collection of thorough details at the time of each report so that any association with kava is clearly defined.
Subject(s)
Kava/adverse effects , Kava/chemistry , Plant Preparations/adverse effects , Data Collection , Dose-Response Relationship, Drug , Drug Interactions , Humans , Plant Preparations/pharmacokinetics , Plant Preparations/pharmacologyABSTRACT
An evidence-based systematic review including scientific evidence, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.
Subject(s)
Lavandula , Oils, Volatile/pharmacology , Oils, Volatile/therapeutic use , Phytotherapy , Plant Extracts/pharmacology , Plant Extracts/therapeutic use , Plant Oils/pharmacology , Plant Oils/therapeutic use , Animals , Dose-Response Relationship, Drug , Humans , Oils, Volatile/adverse effects , Plant Extracts/adverse effects , Plant Oils/adverse effectsABSTRACT
An evidence-based systematic review including scientific evidence, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.
Subject(s)
Phytotherapy , Plant Oils/pharmacology , Plant Oils/therapeutic use , Thymus Plant , Animals , Dose-Response Relationship, Drug , Humans , Plant Extracts/pharmacology , Plant Extracts/therapeutic use , Plant Oils/adverse effectsABSTRACT
An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.
Subject(s)
Boswellia , Evidence-Based Medicine , Plants, Medicinal , Animals , Dose-Response Relationship, Drug , Folklore , Humans , Phytotherapy , Plant Extracts/pharmacology , Plant Extracts/therapeutic useABSTRACT
An evidence-based systematic review including scientific evidence, expert opinion, folkloric precedent, history, pharmacology, kinetics/ dynamics, interactions, adverse effects, toxicology, and dosing.
ABSTRACT
The proposed uses, dosing parameters, adverse effects, toxicology, interactions and mechanism of action of kava is systematically reviewed in monograph format.
ABSTRACT
Red clover, a legume resembling soy is used by man as a phytoestrogen. Other uses include asthma, pertussis, cancer and gout. The authors systematically review this herb in terms of pharmacology, efficacy, safety, side effects, standardization, dosing, toxicology as well as other parameters.
ABSTRACT
The use, adverse effects, mechanism of action, pharmacology, interactions and supporting evidence of shark cartilage is presented. Dosage, toxicology and safety parameters are also discussed.
ABSTRACT
Horse chestnut seed extract (HCSE) is widely used in Europe for the management of chronic venous insufficiency (CVI). Although traditionally recommended for a variety of medical conditions, CVI is the only indication for which there is strong supportive scientific evidence. Review of the literature reveals 14 randomized controlled trials, of which seven are methodologically of high quality, albeit limited by small sample sizes and short durations. These studies support the superiority of HCSE over placebo, and suggest equivalence to compression stockings and to oral oxerutins. In the future, a longer and adequately powered randomized trial is warranted to compare HCSE to standard of care, and to further assess safety and long-term efficacy. There are no data to suggest that horse chestnut flower, raw seed, branch bark, or leaf are effective for any indication, and it is recommended that these products not be used, as they are known to be toxic when ingested.
