[Usher syndrome]. / Sindrom usher.

We present the case report of two brothers, PF-21 years old and PN-19 years old, to whom the fundus examination, perimetry and dark adaptation established the diagnosis of Retinitis Pigmentosa. The otorhinolaryngology exam and the audiogram revealed, in both cases, bilateral sensorineural deafness. The simultaneous presence of these two conditions completes the clinical findings of Usher syndrome. The common ectodermic origin of the retina and the inner ear could explain this pathological association.

[Anterior uveitis in a juvenile chronic arthritis, oligoarticular form]. / Uveita anterioara la un adolescent cu artrita cronica juvenila, forma oligoarticulara.

We present the case of a 16-year-old male teen-ager admitted in the Ophthalmology Clinic Craiova, diagnosed with Anterior neglected acute uveitis in the left eye. Before and simultaneous with the ocular manifestations, the patient complained of pain on the hips joints. The pediatric examination, based on the clinical features and the laboratory findings, diagnosed him with Juvenile chronic arthritis, oligoarthritis type. The evolution was good under the corticosteroid therapy.

[Doyne retinal dystrophy--case report]. / Distrofia retiniana "în fagure de miere" Doyne--prezentare de caz.

We present the case of a female patient, 16-years old, whose the fundus examination revealed the presence, in the macular region, of drusen type lesions; the clinical aspect completed with AFG, perimetry, dark adaptation, ERG resulted in the diagnosis of Doyne's honeycomb retinal dystrophy. The disorder, included in the Familial drusen, is due to an inborn error of metabolism localized the RPE. It seems that the defect is in an intercellular matrix protein which leads to the development of abnormal basement membranes.

[Histopathological changes in pseudoexfoliative syndrome]. / Modificari histopatologice în sindromul exfoliativ.

PURPOSE: The purpose of this study was to analyse the structural modifications of the anterior structures of the human eyes with exfoliation syndrome in optic microscopy. MATERIAL AND METHOD: For this we used bulbar conjunctival fragments and the anterior part of the eyes who were eviscerated for the complications of exfoliative glaucoma. For the optic microscopy the human specimens were preserved in paraffin and stained with hematoxiline-eosine, PAS and Congo red method. RESULTS: We have demonstrated in this study using this three coloration that the abnormal material is exfoliative material and not amyloid in all the ocular structures that were studied (conjunctiva, cornea, lens and ciliary body). CONCLUSIONS: All the anterior structures of the eyes that were examined present typical histopathological alterations of the exfoliation syndrome. The Congo red coloration demonstrate that the abnormal material present in all the structures that were examined is exfoliation material and not amyloid.

[Conjunctival changes in pseudoexfoliative syndrome]. / Modificari conjunctivale in sindromul exfoliativ.

PURPOSE: Histopathologic study of conjunctival biopsy specimens in patients with or without exfoliation syndrome and mature cataract to reveal the presence of exfoliative material. MATERIAL AND METHOD: There were studied a group of patients with different ages who needed surgical cataract extraction; all patients were examined preoperative for the presence of exfoliation syndrome. The conjunctival biopsy specimens were obtained at the end of cataract surgical procedure in eyes both with exfoliation syndrome and in fellow eyes without clinical evidence of the disease. RESULTS: It has been recorded the presence of the exfoliative material in eyes both with exfoliation syndrome and in fellow eyes without clinical evidence of the disease. CONCLUSIONS: Conjunctiva appears to be an independent source of exfoliation material with early detection in preclinical stage of exfoliation syndrome in fellow eyes that appeared to be clinically unaffected.

[Neovascular glaucoma--prevention]. / Glaucomul neovascular--profilaxie.

PURPOSE: The aim of this paper is to analyse the incidence of neovascular glaucoma on a group of patients treated by laser photocoagulation for proliferative diabetic retinopathy and retinal vascular occlusions. MATERIAL AND METHOD: We have studied a group of 277 patients: 112 male and 165 female with ages between 26 and 83 years. 256 patients had proliferative diabetic retinopathy and 21 patients retinal vascular occlusions with ischemic involvement. All this patients were treated with retinal laser photocoagulation. Follow-up period was between 6 months and 2 years. RESULTS: Only 3 patients from the entire group treated with laser photocoagulation had developed neovascular glaucoma. CONCLUSIONS: Prophylactic panretinal photocoagulation is the only method that appears to prevent the neovascular glaucoma and eliminate his devastating complications.

[Incidence of the uveal pseudoexfoliation syndrome in patients with diabetes mellitus]. / Incidenta sindromului de pseudoexfoliere uveala la pacientii cu diabet zaharat.

PURPOSE: To study the incidence of the uveal pseudoexfoliation syndrome in diabetic patients with or without diabetic retinopathy. MATERIAL AND METHOD: There were studied a group of diabetic patients with different ages, with or without diabetic retinopathy; the control group was represented by the non-diabetic patients with similar ages. RESULTS: It has been recorded a high incidence of the uveal pseudoexfoliation syndrome in diabetic patients compare with non-diabetic patients at the same age. CONCLUSIONS: It seems that uveal pseudoexfoliation syndrome is determined by a collagen metabolic alteration which is also present in diabetes mellitus, among other metabolic alterations; this will be the explication for high incidence in diabetic patients.