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2.
Vrach Delo ; (2): 11-4, 1989 Feb.
Article in Russian | MEDLINE | ID: mdl-2711649

ABSTRACT

A study of system of cellular and humoral immunity, unspecific defense in 187 patients with diffuse toxic goiter before and after treatment with mercasolyl revealed that despite the clinical effect, the agent did not essentially influence the content and functional activity of T-lymphocytes. The effect was more favourable on the content of immunoglobulins, titer of antithyroid antibodies. This was observed in mild and average severe course of the disease. It is suggested that mercasolyl effects lymphocytes synthesizing autoantibodies to the thyroid gland.


Subject(s)
Goiter/drug therapy , Methimazole/therapeutic use , Adult , Autoantibodies/biosynthesis , Drug Therapy, Combination , Female , Goiter/immunology , Humans , Immunity, Cellular , Male , Middle Aged , Thyroid Gland/immunology
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