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1.
Rev Mal Respir ; 36(2): 214-218, 2019 Feb.
Article in French | MEDLINE | ID: mdl-30446182

ABSTRACT

INTRODUCTION: Intrathoracic textiloma is a rare complication possibly leading to misdiagnosis. It could present as haemoptysis, lung abscess, pseudo-tumour or a chronic cough. CASE REPORT: A 65-year-old patient with a history of multiple cardiac problems and needing long-term anticoagulation, complained since 2007 of recurrent haemoptysis of increasing abundance, the etiological investigation of which was negative. A thoracic CT-scan revealed a lesion in the lingula in contact with the pericardial plates of an implanted automatic defibrillator dating from 1989. In 2016, after two failures of arterial embolization, a diagnostic and therapeutic surgical exploration was undertaken on this patient who was a high operative risk. A segmental resection revealed an intra-pulmonary textiloma on pathological examination. CONCLUSION: The diagnosis of intrathoracic textiloma remains rare and its late presentation is non specific. Radiological imaging with a CT-scan and/or MRI could lead to the diagnosis. Surgery remains the reference treatment for the diagnosis and cure of intrathoracic textiloma with pathological examination, essential for confirmation. A means of prevention has to be developed because swab count is not totally reliable.


Subject(s)
Foreign Bodies/diagnosis , Hemoptysis/diagnosis , Lung/pathology , Surgical Mesh/adverse effects , Thoracic Surgical Procedures/adverse effects , Aged , Diagnosis, Differential , Foreign Bodies/complications , Foreign Bodies/pathology , Hemoptysis/etiology , Humans , Late Onset Disorders/diagnosis , Late Onset Disorders/etiology , Late Onset Disorders/pathology , Male , Time Factors
3.
Genetika ; 44(1): 54-61, 2008 Jan.
Article in Russian | MEDLINE | ID: mdl-18409387

ABSTRACT

The pivotal-differential model of evolution of polyploid species of cereals has been experimentally reproduced, and the pattern of the formation of a recombinant genome has been analyzed. It has been found that mutual substitution of chromosomes of the original genomes is subjected to selection pressure and, hence, is nonrandom. The selection occurs at the level of homeologs, whose selective advantages are determined by interactions between the genotype and the environment. If a homeolog has distinct selective advantages, the chromosomal composition of the corresponding homeologous group is completed rapidly, which leads to the formation of intergenomic recombination at the level of whole chromosomes. If homeologs have the same competitiveness, the composition of the group is stabilized more slowly. Domination of the genetic systems of the basic genome ensures a high rate of pairing of homeologous chromosomes of the recombinant genome during meiosis, which leads to recombinations at the level of chromosomal segments. It has been demonstrated that different combinations of chromosomes from original genomes are selected at different conditions of plant growth.


Subject(s)
Chromosomes, Plant/genetics , Edible Grain/genetics , Evolution, Molecular , Genome, Plant/genetics , Polyploidy , Recombination, Genetic , Meiosis/physiology
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