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2.
Wounds ; 34(9): E74-E77, 2022 09.
Article in English | MEDLINE | ID: mdl-36252268

ABSTRACT

INTRODUCTION: Autologous homologous skin construct promises to regenerate appendage-bearing skin using a small ellipse of full-thickness tissue that is harvested from the patient and sent to the manufacturer for processing. With so many surgical treatments available for wound management, data on the value and efficacy of this product will play a particularly important role in determining its indications for use. OBJECTIVE: It was hypothesized that the AHSC would be most beneficial in patients who are unable to undergo conventional reconstruction with skin grafts or flaps. The experience of successfully using the product in 2 patients with a relative contraindication to skin grafting is described. CASE REPORTS: The first patient had a history of a collagen genetic mutation and presented after traumatic degloving of the lower extremity, which was initially treated with a dermal regeneration template. The second patient had a previous history of failed skin grafting of a surgical wound following excision of a recurrent nonmelanoma skin cancer of the back. The patients were followed to the end point of complete wound healing at 4 months (case 1) and 5 weeks (case 2). CONCLUSIONS: Although more rigorous medical and financial analysis of this treatment will be necessary, these early data suggest a potential role for the AHSC in the management of wounds for patients who cannot receive conventional techniques for wound coverage.


Subject(s)
Neoplasm Recurrence, Local , Skin Transplantation , Collagen , Humans , Skin/injuries , Skin Transplantation/methods , Wound Healing
3.
Surg Endosc ; 34(6): 2682-2689, 2020 06.
Article in English | MEDLINE | ID: mdl-31399946

ABSTRACT

BACKGROUND: Component separation remains an integral step during ventral hernia repair. Although a multitude of techniques are described, anterior component separation (ACS) via external oblique release (EOR) and posterior component separation (PCS) via transversus abdominis muscle release (TAR) are commonly utilized. The extent of myofascial medialization after ACS or PCS has not been well elucidated. We conducted a comparative analysis of ACS versus PCS in an established cadaveric model. METHODS: Fifteen cadavers underwent both ACS via EOR and PCS via TAR. Following midline laparotomy (MLL), baseline myofascial elasticity was measured. Steps for ACS included creation of subcutaneous flaps (SQF), external oblique release (EOR), and retrorectus dissection (RRD). For PCS, steps included retrorectus dissection (RRD), transversus abdominis muscle division (TAD), and retromuscular dissection (RMD). Maximal advancement of anterior rectus fascia (ARF) was measured following application of tension to the fascia as a whole, and separately at upper, middle, and lower segments. Statistical analysis was performed with Mann-Whitney U test. Values are represented as average myofascial medialization in centimeters. RESULTS: Following MLL an average of 5.0 ± 0.9 cm (range 3.4-6.0 cm) of baseline medialization was obtained. Complete ACS provided 8.8 ± 1.2 cm (range 6.3-10.7 cm) of ARF advancement compared to 10.2 ± 1.7 cm (range 7.6-12.7 cm) with PCS, p = 0.046. In the upper and mid-abdomen, we noted increased ARF advancement with PCS versus ACS (8.1 ± 1.4 cm vs. 6.7 ± 1.2 cm and 11.4 ± 1.5 vs. 9.6 ± 1.4 cm, respectively, p = 0.01). Similar levels of ARF advancement were observed in the lower abdomen, 9.1 ± 1.7 cm versus 8.7 ± 1.8 cm, p = 0.535. CONCLUSIONS: Component separation via both anterior and posterior approaches provide substantial myofascial advancement. In our model, we noted statistically greater anterior fascial medialization after PCS versus ACS as a whole, and especially in the upper and mid-abdomen. We advocate PCS as a reliable and possibly superior alternative for linea alba restoration for reconstructive repairs, especially for large defects in the upper and mid-abdomen.


Subject(s)
Hernia, Ventral/surgery , Herniorrhaphy/methods , Cadaver , Female , Humans , Male
4.
Cleft Palate Craniofac J ; 56(1): 90-93, 2019 01.
Article in English | MEDLINE | ID: mdl-29787301

ABSTRACT

BACKGROUND: Cherubism is an autosomal dominant syndrome characterized by excessive bilateral maxillomandibular bony degeneration and fibrous tissue hyperplasia. Conservative management is the preferred treatment as cherubism has a self-limiting course. Functional or emotional disturbances may, however, demand surgical intervention. We report a patient who underwent surgical intervention. METHOD/DESCRIPTION: He had significant enlargement of lower cheeks and bilateral lower lid scleral show. On computed tomography of the face, the patient had significant fibrous tissue involving bilateral maxilla and mandible. The mandibular tumor was excised. Given normal inferior border, bilateral sagittal split osteotomy was performed to infracture and inset the outer cortex. During the procedure, patient required blood transfusion intraoperatively, so the maxillary portion of the procedure was delayed until 6 months later. For the maxilla, bilateral transconjunctival approach was used to resect parts of the orbital floors that were concave, resulting in 1 × 2 cm defects bilaterally which were reconstructed using resorbable plates. Then the anterior maxillary tumor was excised. RESULTS: The patient and his parents were satisfied with his appearance after surgery. The patient was noted to have improvement in contour and decreased scleral show. He has most recently followed up 15 months after the initial surgery. There were no long-term complications. CONCLUSIONS: Severity of cherubism influences the type of surgical intervention. The present case is innovative because this is the first reported case of recontouring orbital floors with resorbable plates and infracturing of the mandible using sagittal split osteotomies for surgical treatment of cherubism.


Subject(s)
Cherubism , Orbit , Cherubism/complications , Cherubism/diagnostic imaging , Cherubism/surgery , Humans , Male , Mandible/surgery , Maxilla/surgery , Orbit/abnormalities , Orbit/surgery , Tomography, X-Ray Computed
6.
Stereotact Funct Neurosurg ; 95(6): 385-391, 2017.
Article in English | MEDLINE | ID: mdl-29232685

ABSTRACT

BACKGROUND: Scalp erosion in patients with deep brain stimulation (DBS) hardware is an uncommon complication that lacks a clearly defined management strategy. Previous studies have described various therapies including conservative treatment with antibiotics and surgical debridement with or without hardware removal. OBJECTIVES: The aim of this study was to review the efficacy of a hardware-sparing management strategy for the treatment of scalp erosion. METHODS: Five patients with previous DBS implantation presented with scalp erosion and visible hardware exposure at the calvarial burr hole site, and underwent tension-free, vascularized, rotational scalp flap, with preservation of the leads under the pericranium. Two of the procedures were performed after an unsuccessful attempt at primary closure and 3 as a primary procedure. Each patient was followed clinically for at least 14 months postoperatively to evaluate for wound-healing and adverse effects. RESULTS: The median duration from initial DBS hardware implantation to erosion and revision surgery was 12 months (range 1.5-62 months). Three patients were documented to have positive intraoperative cultures in spite of the absence of purulence. At the last follow-up, all patients were noted to have complete wound-healing and no evidence of infection or erosion. CONCLUSIONS: DBS scalp erosion can be managed by rotational scalp flap without hardware removal, even in cases where infection is identified.


Subject(s)
Deep Brain Stimulation/adverse effects , Disease Management , Reoperation/methods , Scalp/pathology , Scalp/surgery , Aged , Deep Brain Stimulation/instrumentation , Female , Humans , Male , Middle Aged , Retrospective Studies
7.
Plast Reconstr Surg ; 140(6): 775e-781e, 2017 Dec.
Article in English | MEDLINE | ID: mdl-29176411

ABSTRACT

The American Society of Plastic Surgeons commissioned the Breast Reconstruction Performance Measure Development Work Group to identify and draft quality measures for the care of patients undergoing breast reconstruction surgery. Two outcome measures were identified. The first desired outcome was to reduce the number of returns to the operating room following reconstruction within 60 days of the initial reconstructive procedure. The second desired outcome was to reduce flap loss within 30 days of the initial reconstructive procedure. All measures in this report were approved by the American Society of Plastic Surgeons Breast Reconstruction Performance Measures Work Group and the American Society of Plastic Surgeons Executive Committee. The Work Group recommends the use of these measures for quality initiatives, Continuing Medical Education, Maintenance of Certification, American Society of Plastic Surgeons' Qualified Clinical Data Registry reporting, and national quality reporting programs.

8.
J Craniofac Surg ; 28(3): 693-695, 2017 May.
Article in English | MEDLINE | ID: mdl-28468150

ABSTRACT

BACKGROUND: Craniofacial teams employ multidisciplinary clinics to optimize patient care. Different clinic formats exist among teams. Formats include providers rotating from room to room as separate specialties, patients rotating from room to room to either separate specialties or as 1 group, as well as providers rotating together as 1 group. Surveys were used to study family preferences between the different formats and to compare them with trends of national practices. METHODS: Families of the authors' team clinic patients were surveyed from November 2012 to February 2013, after a clinic format change from patients moving between rooms to see providers, to providers moving between rooms to see patients. This survey focused on patient satisfaction, clinic format preference, and their perception of efficiency. A second, national survey was distributed to 161 American craniofacial teams approved by the American Cleft Palate-Craniofacial Association to survey clinic formats, provider satisfaction, and experience with other formats. Institutional survey data were tabulated as percentages and further analyzed using the Mann-Whitney Test. The national survey data was then tabulated and compared with authors' institutional results. RESULTS: Thirty-nine of 54 (72.2%) families responded to the institutional survey. Providers moving between rooms were associated with greater patient satisfaction (mean 4.8 of 5, 5 being most satisfied) (0<0.0001), shorter perceived clinic time (76.9%), and an increased sense of comfort (84.6%). The difference in satisfaction rates was statistically significant (P <0.0001) between the primary clinic formats of providers rotating (mean of 4.8) and patients rotating (mean of 2.4).The national survey had 93 responses of 161 (57.7%). 54.9% of respondents have providers rotating between examination rooms, and 32.3% have patients moving between rooms. Other formats included the entire team moving as a group between rooms (10.8%) and specialties sitting together in 1 room while patients rotate (9.7%). Respondents were satisfied with current formats (mean 4.24 of 5, 5 being most satisfied). 22.2% had tried a different format previously. CONCLUSION: The most common American cleft and craniofacial clinic format is providers moving between rooms; however, all formats have high provider satisfaction. At our institution, patients prefer when providers move between rooms. Our study suggests that clinic formats do not need to be standardized, and the clinic format utilized should be tailored to the individual needs of the institution.


Subject(s)
Cleft Palate/surgery , Oral Surgical Procedures/standards , Patient Satisfaction , Plastic Surgery Procedures/standards , Societies, Medical , Adolescent , Child , Child, Preschool , Female , Humans , Male , Surveys and Questionnaires , United States
9.
Surg Obes Relat Dis ; 13(2): 144-149, 2017 Feb.
Article in English | MEDLINE | ID: mdl-28029599

ABSTRACT

BACKGROUND: Abdominoplasty is increasingly performed after weight loss surgery. However, performing a laparoscopic sleeve gastrectomy (LSG) after abdominoplasty poses technical challenges. OBJECTIVE: The present study aimed to compare operative events and postoperative outcomes between LSG patients with and without a history of prior abdominoplasty. SETTING: University hospital, Qatar. METHODS: A case-control study was conducted on 2 groups of patients with (n = 33) and without (n = 69) prior abdominoplasty who underwent LSG. Patient demographics, baseline characteristics, as well as operative and postoperative events were compared between the 2 groups. RESULTS: A total of 102 patients with an average age of 39.6±7.7 years and body mass index (BMI) of 42.8±5.9 kg/m2 were included. There were no significant differences between the 2 groups in terms of demographic characteristics, preoperative BMI, and co-morbidities. The number of ports required was significantly higher in the LSG patients with a history of prior abdominoplasty than in the nonabdominoplasty patients. The operation time was also significantly longer in the abdominoplasty patients than in the nonabdominoplasty patients (90.3±36.7 minutes versus 57.1±17.7 minutes; P<.0001). However, no significant differences were observed in terms of postoperative complications, length of hospital stay, and weight loss results. CONCLUSION: LSG after abdominoplasty is associated with longer operative times and the need for additional port placement to overcome the decreased working space. However, operative strategies should be considered to overcome the technical challenges during LSG in patients who underwent a prior abdominoplasty.


Subject(s)
Abdominoplasty , Gastrectomy/methods , Laparoscopy/methods , Adolescent , Adult , Aged , Bariatric Surgery/instrumentation , Bariatric Surgery/methods , Case-Control Studies , Female , Gastrectomy/instrumentation , Humans , Laparoscopy/instrumentation , Length of Stay/statistics & numerical data , Middle Aged , Obesity, Morbid/surgery , Operative Time , Postoperative Complications/etiology , Prospective Studies , Retrospective Studies , Second-Look Surgery , Surgical Instruments/statistics & numerical data , Treatment Outcome , Young Adult
10.
J Craniofac Surg ; 27(2): 356-60, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26825746

ABSTRACT

BACKGROUND: A multidisciplinary approach to patients with craniofacial abnormalities is the standard of care by the American Cleft Palate-Craniofacial Association (ACPA). The standards of team care, however, do not require provision of social support services beyond access to a social worker. The purpose of this investigation is to study social support services provided by ACPA teams, funding sources for services, and family interest in services. METHODS: A survey was submitted to ACPA cleft and craniofacial team leaders (N = 161), which evaluated the provision of potentially beneficial social support services, and their funding sources. A second survey administered to patient families at our institution gauged their level of interest in these services. Statistical analysis evaluated the level of interest among services. RESULTS: Seventy-five of 161 (47%) teams and 39 of 54 (72%) families responded to the surveys. Services provided included scholarships (4%), summer camp (25%), social media (32%), patient support groups (36%), parties (42%), parent support groups (46%), other opportunities (56%), and social workers (90%). The majority of funding for social workers was by the institution (61%) whereas funding for ancillary services varied (institution, team, fundraisers, grants, and other sources). Families indicated an average interest of 2.4 ±â€Š1.41 for support groups, 2.5 ±â€Š1.63 for summer camps, 2.92 ±â€Š1.66 for parties, 3.16 ±â€Š1.65 for social media, and 3.95 ±â€Š1.60 for scholarships (P value <0.05). CONCLUSIONS: The ACPA standards of team care do not require teams to provide social support services beyond access to a social worker. Among our survey respondents, the authors found that in addition to a social worker, teams offered social support services, which were not required. The social worker position is usually institutionally funded, whereas funding sources for additional services varied. Respondents at our center desired additional social support services. The authors recommend a hybrid model of hospital and nonhospital funding to provide social and support services to patients with craniofacial deformities.


Subject(s)
Cleft Palate/therapy , Craniofacial Abnormalities/therapy , Health Facilities , Patient Care Team , Social Support , Social Work , Surveys and Questionnaires , Female , Humans , Male
11.
J Plast Reconstr Aesthet Surg ; 69(2): 221-6, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26654701

ABSTRACT

The superficial inferior epigastric vasculature plays a critical role in free abdominal tissue transfer. However, its anatomic variations are incompletely characterized. An investigation was conducted on the preoperative imaging of patients undergoing free-flap breast reconstruction by a single surgeon between 2008 and 2013. This study included patients who underwent abdominal magnetic resonance angiogram (MRA). A coordinate system was used to draw the main trunk and primary branches from each patient's superficial inferior epigastric system. Each hemiabdomen's branching pattern was categorized as simple, complex, or absent. The number of superficial-to-deep inferior epigastric connections and the presence or absence of a superficial system crossing the midline were recorded. Interrater reliability was assessed for two raters. This analysis included 53 patients (106 hemiabdomens). A total of 80 (75%) hemiabdomens were categorized as having simple and 10 (9%) as complex branching patterns. A total of 16 (15%) hemiabdomens had no identifiable vessels. At least one superficial-to-deep connection was found among 89 hemiabdomens (84%). Superficial systems crossing the midline were found in 14 patients (26%). Our findings support the high degree of anatomic variation in the superficial inferior epigastric system, including a significant number of patients lacking superficial-to-deep connections and bilaterally communicating systems. These variations may be identified on preoperative MRA.


Subject(s)
Abdominal Muscles/transplantation , Epigastric Arteries/anatomy & histology , Free Tissue Flaps/blood supply , Magnetic Resonance Angiography/methods , Mammaplasty/methods , Abdominal Muscles/blood supply , Female , Follow-Up Studies , Humans , Reproducibility of Results , Retrospective Studies
12.
Plast Reconstr Surg ; 136(6): 815e-829e, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26595037

ABSTRACT

LEARNING OBJECTIVES: After studying this article, the participant should be able to: 1. Understand the existing principles for lower extremity reconstruction for both traumatic and ablative defects. 2. Understand the important factors for lower extremity reconstruction-based anatomical regions. 3. Discuss perforator flaps and their application in lower extremity reconstruction. SUMMARY: The Gustilo-Anderson open fracture classification is briefly reviewed. A comprehensive overview of the available flaps and methods for lower extremity reconstruction is provided.


Subject(s)
Lower Extremity/surgery , Plastic Surgery Procedures/methods , Amputation, Surgical , Humans , Surgical Flaps
13.
J Plast Reconstr Aesthet Surg ; 68(12): 1719-26, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26526860

ABSTRACT

OBJECTIVE: Limited data exist regarding the effect of radiation timing on complications of tissue expander/implant-based breast reconstruction. This study seeks to compare outcomes of tissue expander/implant reconstruction in patients undergoing postmastectomy radiotherapy, those with previous radiation therapy following breast conservation therapy, and those who did not receive radiation therapy. METHODS: The records of the patients of a single surgeon were reviewed from January 2007 to July 2013. All patients undergoing tissue expander/implant breast reconstruction were placed into one of three groups based on the timing of radiation therapy: postmastectomy (Current), previously following breast conservation therapy (Prior), and no radiotherapy (No XRT). Medical records were reviewed for any reported complications, and statistical analysis was performed. RESULTS: A total of 210 patients (265 breasts) were included in the analysis. Current patients were more likely than No XRT patients to experience expander infection (20% vs. 2.6%, p = 0.001) and expander removal (26% vs. 8.3%, p = 0.007). Prior patients were more likely than No XRT patients to undergo conversion to tissue flap reconstruction (10.5% vs. 0.6%, p = 0.031). No significant differences were found between groups with respect to cellulitis, abscess formation, hematoma, seroma, skin flap necrosis, expander exposure, implant exposure, or implant infection. CONCLUSIONS: This study supports the relative safety of tissue expander/implant breast reconstruction in selected groups of patients who have received radiation therapy. Differences in rates of expander infection, expander removal, and conversion to tissue flap reconstruction represent potential areas for further research.


Subject(s)
Breast Implants , Breast Neoplasms/radiotherapy , Breast Neoplasms/surgery , Mammaplasty/methods , Female , Humans , Mastectomy , Middle Aged , Postoperative Complications , Retrospective Studies , Risk Factors , Time Factors , Tissue Expansion , Tissue Expansion Devices , Treatment Outcome
14.
Adolesc Health Med Ther ; 6: 159-63, 2015.
Article in English | MEDLINE | ID: mdl-26366109

ABSTRACT

Fibroadenomas are one of the most common benign tumors of the breast in the adolescent population. They account for 68% of all breast masses and 44%-94% of all biopsied breast lesions. Fibroadenomas can range from asymptomatic masses to painful and rapidly growing tumors that can cause significant esthetic distortions of the breast. Given the prevalence of fibroadenomas in the adolescent population and the psychosocial morbidity of finding a mass in the adolescent breast, it is imperative for physicians treating adolescent patients to be familiar and up to date with this disease process. The goal of this article is to provide a brief review of the classification, etiology, symptoms, initial work-up, and update on the management of breast fibroadenomas in the adolescent population.

15.
Surgery ; 156(1): 183-9, 2014 Jul.
Article in English | MEDLINE | ID: mdl-24856669

ABSTRACT

INTRODUCTION: Biologic matrices used in abdominal wall reconstruction are purported to undergo remodeling into connective tissue resembling native collagen. Key steps in that process include inflammatory response at the mesh/tissue interface, cellular penetration, and neovascularization of the matrix, followed by fibroblast proliferation and collagen deposition. We aimed to examine the concept of biologic mesh remodeling/regeneration in a series of explanted porcine biologic meshes. MATERIALS AND METHODS: A cohort of patients who underwent removal of porcine biologic mesh was identified in a prospective database. Mesh/tissue samples were analyzed using standard hematoxylin/eosin and Masson's trichrome staining. Main outcome measures included: inflammatory response at the mesh/tissue interface, foreign body reaction (FBR), cellular penetration, neovascularization, and new collagen deposition. All evaluations were performed by a blinded senior pathologist using established grading scales. RESULTS: A total of 14 cases with implant time ranging from 4 to 33 months were identified and analyzed. All meshes were placed as intraperitoneal underlay. There were 7 non-cross-linked and 7 cross-linked grafts. Cross-linked grafts were associated with mild FBR and moderate fibrous capsule formation. Similarly, non-cross-linked grafts had mild-to-moderate FBR and encapsulation. Furthermore, non-cross-linked grafts were associated with no neovascularization and minimal peripheral mesh neocellularization. Cross-linked grafts demonstrated neither neovascularization nor neocellularization. Although no grafts were associated with any quantifiable new collagen deposition within the porcine biologic matrix, minimal biodegradation/remodeling was observed at the periphery of the non-cross-linked grafts only. CONCLUSION: The biologic behavior of porcine meshes is predicated on their ability to undergo mesh remodeling with resorption and new collagen deposition. In the largest series of human biologic explants, we detected no evidence of xenograft remodeling, especially in the cross-linked group. Although underlay mesh placement and other patient factors may have contributed to our findings, the concept of porcine biologic mesh regeneration does not seem to be prevalent in the clinical setting.


Subject(s)
Biocompatible Materials , Collagen , Foreign-Body Reaction , Neovascularization, Physiologic , Surgical Mesh , Biomarkers/metabolism , Collagen/metabolism , Female , Foreign-Body Reaction/pathology , Foreign-Body Reaction/physiopathology , Humans , Male , Middle Aged , Single-Blind Method
16.
Plast Reconstr Surg ; 133(1): 32-39, 2014 Jan.
Article in English | MEDLINE | ID: mdl-24105087

ABSTRACT

BACKGROUND: The incidence of obesity is on the rise in the United States and worldwide. Complications following panniculectomy are higher for super obese patients, often requiring readmission and additional interventions. In this study, the authors compare the outcomes of patients who underwent primary closure of their resection wounds to the outcomes of patients who underwent initial open wound management with a negative-pressure dressing. METHODS: The records of all patients who underwent panniculectomy between 2007 and 2012 were reviewed. Of 14 patients with a body mass index greater than 50, nine underwent primary closure and five were treated with open wound management. A retrospective chart review was performed. RESULTS: There were no statistically significant differences in age or preoperative comorbidities, but body mass index was higher for the open wound management group (66.4 versus 58.9, p = 0.039). There were no statistically significant differences in mean operative time, resection weight, estimated blood loss, or hospital length of stay. The primary closure group had a 44 percent readmission rate and a 33 percent reoperation rate for wound complications. The open wound management group had no wound-related readmissions or secondary procedures for débridement. CONCLUSIONS: Open wound management in the massive panniculectomy patient reduces hospital readmission and secondary operations. This case series provides reasons to support the consideration of open wound management following massive panniculectomy in the super morbidly obese patient population.


Subject(s)
Abdominal Wound Closure Techniques , Abdominoplasty/methods , Negative-Pressure Wound Therapy/methods , Obesity, Morbid/surgery , Postoperative Complications/prevention & control , Aged , Blood Loss, Surgical , Body Mass Index , Comorbidity , Female , Humans , Incidence , Length of Stay , Male , Middle Aged , Obesity, Morbid/epidemiology , Patient Readmission , Retrospective Studies , Severity of Illness Index , Wound Healing
17.
Aesthet Surg J ; 32(7): 846-60, 2012 Sep.
Article in English | MEDLINE | ID: mdl-22942112

ABSTRACT

BACKGROUND: Appearance, aging, and disorders of the breast are multifactorial. There are intrinsic, patient-specific characteristics, such as breast growth during puberty and propensity for breast cancer, which are primarily inherited. There are also environmental factors, which can be potentially controlled. Monozygotic twins provide an excellent research opportunity to examine the role of extrinsic factors in subjects with identical genetic predispositions. OBJECTIVES: The authors investigate the role and significance of various environmental and acquired factors on breast aesthetics. METHODS: Identical female twins were recruited during the Twins Days Festival in Twinsburg, Ohio, in 2009 and 2010. After consent was obtained, enrolled subjects completed a comprehensive survey on their medical and personal history. Standardized digital photographs were taken by medical photographers. Sixteen aesthetic breast features were subjectively rated by 6 plastic surgery residents blinded to the survey results. These ratings were then analyzed against survey data to determine the significance of different exogenous factors on breast appearance. RESULTS: A total of 161 pairs of identical female twins (n = 322) with a mean (SD) age of 47.6 (14.5) years were recruited. Twins who moisturized their skin daily had significantly fewer rhytids (P = .002). Twins who received hormone replacement therapy after menopause had more attractive breast shape, size, projection, areolar shape, and areolar size (P < .03). However, twins who had a higher body mass index, greater number of pregnancies, and larger cup sizes had significantly less attractive breasts (P < .05). Twins who smoked cigarettes and consumed alcohol also had significantly less attractive breasts (P < .05). Twins who breastfed had less attractive areolar size and shape but better skin quality than their counterparts who never breastfed (P < .03). Finally, there was a significantly higher incidence of breast pain in twins who primarily slept on their sides compared with twins who primarily slept on their backs (P < .008). CONCLUSIONS: This study implicates several environmental factors that significantly affect the aesthetic quality of breasts.


Subject(s)
Breast/anatomy & histology , Twins, Monozygotic , Adult , Aged , Aging , Alcohol Drinking/epidemiology , Body Mass Index , Breast Feeding , Female , Hormone Replacement Therapy/methods , Humans , Middle Aged , Photography , Postmenopause , Reproductive History , Single-Blind Method , Smoking/adverse effects
18.
Am Surg ; 78(5): 540-4, 2012 May.
Article in English | MEDLINE | ID: mdl-22546125

ABSTRACT

The umbilicus is the main access route to the abdominal cavity in laparoscopic surgeries. However, its anatomical configuration is rarely studied in the surgical and anatomical literature. With introduction of laparoendoscopic single-site surgery and considering the significant number of primary and postoperative umbilical hernias, we felt the necessity to comprehensively study the umbilical structures and analyze their protective function against hernias. Twenty-four embalmed cadavers were studied in the anatomy laboratory of Case Western Reserve University. Round hepatic, median and medial ligaments, umbilical ring, umbilical and umbilicovesicular fasciae, and pattern of attachment to the ring were dissected and measured. Mean age was 82.1 years, ranging between 56 and 96 years, with a male-to-female ratio of 1.4:1. Ninety-two per cent was white and 8 per cent black adults. According to shape and attachment pattern of ligaments, umbilical ring is classified into five types. Hernia incidence was 25 per cent. All hernia cases lacked the umbilical fascia and the round hepatic ligament was not attached to the inferior border of the ring. The umbilical ring and its morphologic relation with adjacent ligaments are described and classified into five types. In contrary to sparse existing literature, we propose that umbilical fascia is continuation and condensation of umbilicovesicular rather than transversalis fascia. It was absent in cadavers forming conjoined median and medial ligaments with a single insertion site to the ring. Round ligament insertion to the inferior border of the ring provides another protective factor. These two protective measures were absent in all the observed umbilical hernias.


Subject(s)
Anatomy, Regional/methods , General Surgery/education , Hernia, Umbilical/surgery , Herniorrhaphy/education , Umbilicus/anatomy & histology , Umbilicus/surgery , Abdominal Wall/anatomy & histology , Abdominal Wall/surgery , Aged , Aged, 80 and over , Cadaver , Female , Herniorrhaphy/methods , Humans , Male , Middle Aged
19.
J Plast Reconstr Aesthet Surg ; 65(10): e267-80, 2012 Oct.
Article in English | MEDLINE | ID: mdl-22633392

ABSTRACT

Breast reconstruction following mastectomy has become, in many centers the standard of care. An increasingly encountered trend is the use of neoadjuvant chemotherapy to downstage high stage tumors and to decrease tumor burden prior to definitive oncologic surgery. These agents clearly provide a survival benefit, but also have the potential to adversely affect the surgical course of immediate and delayed breast reconstruction. The use of new biologic and hormonal agents may also have effects on surgery and reconstruction. Furthermore, chemotherapeutic agents as a whole may impair cellular functions necessary for normal recovery from surgery. In this paper we present a concise review for the reconstructive surgeon on adverse effects of chemotherapeutic, hormonal and biologic agents used for treatment of breast cancer, important perioperative issues, and also discuss their potential effect on breast reconstruction.


Subject(s)
Chemotherapy, Adjuvant/adverse effects , Graft Rejection/prevention & control , Mammaplasty/methods , Mastectomy/methods , Neoadjuvant Therapy/adverse effects , Adult , Age Factors , Aged , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Biological Products/adverse effects , Biological Products/therapeutic use , Breast Neoplasms/pathology , Breast Neoplasms/surgery , Female , Hormone Replacement Therapy/adverse effects , Hormone Replacement Therapy/methods , Humans , Mammaplasty/adverse effects , Middle Aged , Postoperative Care/methods , Prognosis , Risk Assessment , Wound Healing/drug effects
20.
J Plast Reconstr Aesthet Surg ; 65(7): 924-30, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22406261

ABSTRACT

BACKGROUND: Many surgeons now incorporate Acellular Dermal Matrix (ADM) into expander-based breast reconstruction. ADM is safe, provides full expander coverage, eliminates the need for additional muscular dissection and has improved aesthetic outcomes. However, its use increases surgical costs. Whether this cost is offset by decreased operative times or a reduced number of revision procedures is unknown. METHODS: We have developed a new technique that minimises the amount of ADM required in many patients. The 'partial sling' approach has been used for 145 consecutive patients (197 breasts) by a single surgeon from 2007 to 2010. After mastectomy, any portion of the pectoralis major insertion at, or <1 cm from, the planned inframmary fold is left intact and becomes the inferior margin of the expander pocket. The minimal size of ADM required is then determined by measuring from the pectoralis to the lateral breast margin. In this study, we exclusively used AlloDerm. Preoperative breast measurements, intra-operative fill volume, time to exchange procedure, number of expansion procedures and complications were recorded for all patients. RESULTS: Patients were grouped according to the surface area (cm(2)) of ADM required. Good aesthetic outcomes were obtained in all groups. Two groups had a significant difference in intra-operative fill volumes but this did not correlate to an increase in the number of expansion procedures required. Of 197 reconstructed breasts less than 64 cm(2) of ADM was used for 40 breasts (20%). CONCLUSIONS: The partial AlloDerm sling can minimise the costs associated with ADM use in breast reconstruction for many patients without increasing complications or altering aesthetic outcomes.


Subject(s)
Breast Implants , Breast Neoplasms/surgery , Collagen/therapeutic use , Mammaplasty/methods , Mastectomy , Skin, Artificial , Tissue Expansion Devices , Adult , Aged , Chi-Square Distribution , Collagen/economics , Female , Humans , Middle Aged , Postoperative Complications , Retrospective Studies , Treatment Outcome
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