ABSTRACT
Three autochthonous cases of cutaneous-ganglionar rickettsiosis transmitted by dogs ticks (Amblyomma maculatum in one of them) are reported. Two of the three cases were undoubtely produced by Rickettsia conorii according to the results of the specific indirect immunofluorescence technique IEF-IgM anti R. conorii. A third case is included due to the clinical epidemiological similarity, the positive serum reactivity with Proteus O x 19 and the rapid response to tetracycline. Autochthonous rickettsiosis by R. conorii has not been previously registered in the American area what confers special interest to this communication. The search of the disease in the other countries of the region is suggested.
Subject(s)
Boutonneuse Fever/epidemiology , Skin Diseases, Infectious/epidemiology , Adolescent , Animals , Bites and Stings/complications , Boutonneuse Fever/diagnosis , Boutonneuse Fever/drug therapy , Boutonneuse Fever/transmission , Child , Female , Humans , Male , Serologic Tests , Skin Diseases, Infectious/diagnosis , Skin Diseases, Infectious/drug therapy , Skin Diseases, Infectious/transmission , Ticks/microbiology , Uruguay/epidemiologyABSTRACT
Los autores hacen una revisión de la problemática referida a la fiebre Q, tanto desde el punto de vista clínico como epidemiológico. El primer caso nacional se comunicó en el año 1956, en un adulto, obrero de frigorífico. En 1966 se comunica el primer caso en un niño. A partir de esa fecha se realizan varias encuestas serológicas en humanos y en animales. En seres humanos los hallazgos varían entre 4,2% y 5,5% según el año estudiado. En animales se hallaron valores que oscilaron entre 0.9% (animal para abasto) y 30% (animal tipo industria) para bovinos. En ovinos, en el único estudio se halló un 10,3% de positivos. En equinos los valores de positividad variaron de 5,5% a 21.7%. En suinos se refiere un porcentaje de positividad del 21.2% en la primera encuesta, sendo en la más reciente del 0.0%. En aves y cobayos no se evidenciaron sueros positivos. Entre 1975 y 1985 los autores estudiaron 14 brotes en seres humanos en establecimentos de procesamiento de carne, con un total de 1358 casos estudiados, habiéndose confirmado el 60% de ellos. Pasan revista a la sintomatología común, así como el tipo de tarea de los pacientes. Para los estudios serológicos, como los diagnósticos de los casos clínicos, los autores utilizaron la fijación del complemento, la aglutinación capilar y la microaglutinación en lámina
Subject(s)
Child , Adult , Cattle , Animals , Humans , Q Fever/epidemiology , Disease Outbreaks/epidemiology , Horses , Q Fever/diagnosis , Serologic Tests , Sheep , Swine , UruguaySubject(s)
Disease Outbreaks/epidemiology , Q Fever/epidemiology , Adult , Animals , Cattle , Child , Horses , Humans , Q Fever/diagnosis , Q Fever/transmission , Serologic Tests , Sheep , Swine , UruguayABSTRACT
The first outbreak of Q fever in Uruguay occurred in 1956. The infection, which is caused by Coxiella burnetti, occurs in sheep, cattle, swine, and horses, but not in fowl or guinea pig. Most of the cases studied have been traced to cattle. Fourteen outbreaks of this disease were studied between 1975 and 1985. All of the 1,358 clinically suspected cases (814 serologically confirmed) reported in Uruguay occurred in workers at meat-processing plants. Diagnoses of cases and serologic surveys were made by use of complement fixation, capillary agglutination, and layer microagglutination techniques.
Subject(s)
Antibodies, Bacterial/analysis , Coxiella/immunology , Disease Outbreaks , Q Fever/epidemiology , Agglutination Tests , Animals , Complement Fixation Tests , Humans , Meat-Packing Industry , Q Fever/veterinary , UruguaySubject(s)
Measles virus/immunology , Multiple Sclerosis/immunology , Adult , Antibodies, Viral/analysis , Female , Humans , Immunity, Cellular , Male , Middle AgedABSTRACT
Avian plague virus was used as antigen in a counterimmunoelectrophoresis technique. This virus was selected because it detects only type-specific influenza A antibodies in human sera, avoiding the possible interference of other antigens with anodic migration. The results with reference sera, as well as the correlation of positive sera found by counterimmunoelectrophoresis and complement fixation with the proposed antigen, in the absence of other types of antibodies to fowl plague virus antigen, support the conclusion that the counterimmunoelectrophoresis technique reveals type-specific antibodies. The test is more sensitive than immunodiffusion but less sensitive than complement fixation. Its sensitivity, simplicity, and rapidity make it suitable for serologic surveys of human influenza A.
