ABSTRACT
The authors present a report on the case of a female patient with myelofibrosis where X-ray examinations of the bone skeleton predominantly showed such osteolytic changes which are no typical of myelosclerosis. Morphological criteria rather would have corresponded to osteitis fibrosa cystica generalisata. Laboratory examinations partially indicated primary hyperparathyroidism, this assumption could not be confirmed by other examinations. Also histological findings of repeated bone biopsies did not lead to a uniform diagnosis. Autopsy confirmed the presence of both diseases. The authors consider the synergistic effect of both diseases to be the cause for the development of those bone changes mentioned above.
Subject(s)
Bone Resorption/etiology , Hyperparathyroidism/complications , Osteolysis/etiology , Primary Myelofibrosis/complications , Diagnosis, Differential , Female , Humans , Hyperparathyroidism/diagnosis , Liver/pathology , Lymph Nodes/pathology , Middle Aged , Osteolysis/diagnosis , Primary Myelofibrosis/diagnosis , Spleen/pathologySubject(s)
Brain Diseases/complications , Brain Injuries/complications , Adult , Aged , Brain Diseases/diagnostic imaging , Brain Injuries/diagnostic imaging , Brain Neoplasms/diagnostic imaging , Carotid Artery Diseases/diagnostic imaging , Cerebral Angiography , Diagnosis, Differential , Humans , Male , Middle AgedABSTRACT
The dicephalus dibrachius twin malformation is a rare developmental anomaly. Spontaeous birth is impossible. Prenatal diagnosis of this condition is difficult though essential to prevent danger to the life of the mother. Radiological examination before birth is necessary. Auscultation and bimanual examination only may lead to the erroneous diagnosis of a twin pregnancy, as in this case, where in the end a cesarean sectionwas performed because unseparated twins were suspected.