Subject(s)
Carcinoid Tumor/pathology , Ileal Neoplasms/pathology , Lymphoma, Large B-Cell, Diffuse/pathology , Neoplasms, Multiple Primary/pathology , Aged , Fatal Outcome , Humans , Ileal Neoplasms/chemistry , Ki-1 Antigen/analysis , Leukocyte Common Antigens/analysis , Lymphoma, Large B-Cell, Diffuse/chemistry , Male , Phosphopyruvate Hydratase/analysisSubject(s)
Adenocarcinoma/diagnosis , Mesothelioma/diagnosis , Neoplasms, Second Primary/diagnosis , Sigmoid Neoplasms/diagnosis , Adenocarcinoma/surgery , Aged , Colon, Sigmoid/pathology , Colon, Sigmoid/surgery , Diagnosis, Differential , Fatal Outcome , Humans , Male , Mesothelioma/surgery , Neoplasms, Second Primary/surgery , Sigmoid Neoplasms/surgeryABSTRACT
We describe a case of renal-cell carcinoma insulated and entrapped in the renal capsule by a calcified and ossified rim. To our knowledge, this is the first time a renal-cell carcinoma of the renal capsule is reported. The fact that the tumor cells originated from the distal/medullary tubules was supported by immunohistochemical studies. The pertinent literature is reviewed.
Subject(s)
Calcinosis/pathology , Carcinoma, Renal Cell/pathology , Kidney Neoplasms/pathology , Kidney/pathology , Calcinosis/diagnostic imaging , Carcinoma, Renal Cell/diagnostic imaging , Humans , Kidney Neoplasms/diagnostic imaging , Male , Middle Aged , Tomography, X-Ray ComputedABSTRACT
An unusual case of a double testicular tumor, with different histology and the same marker chromosome, led to a search of the literature for cases of testicular tumors that were double, bilateral, or familial. The literature on abnormal chromosomes in tumors of the testis is also reviewed. After a discussion of the facts, it is suggested that most of the histological variants of germ cell tumors of the testicle are so closely related that they could be grouped together under the title of 'orchidomata'.
Subject(s)
Chromosome Aberrations , Neoplasms, Germ Cell and Embryonal , Testicular Neoplasms , Testis/pathology , Humans , Male , Neoplasms, Germ Cell and Embryonal/genetics , Neoplasms, Germ Cell and Embryonal/pathology , Testicular Neoplasms/genetics , Testicular Neoplasms/pathologyABSTRACT
An identical abnormal chromosome, i(12p), and a marker chromosome of unknown origin were seen in 2 tumors of different histology (seminoma and embryonal carcinoma) in the same testis. A younger brother of the patient also had undergone orchiectomy for 2 seminomas in the left testis 2 years previously. These findings are discussed in relation to the possible cellular background of testicular tumors and their genetic parameters.
Subject(s)
Chromosome Aberrations , Chromosomes, Human, Pair 12 , Dysgerminoma/genetics , Neoplasms, Multiple Primary/genetics , Teratoma/genetics , Testicular Neoplasms/genetics , Adult , Chromosome Banding , Dysgerminoma/pathology , Humans , Karyotyping , Male , Neoplasms, Multiple Primary/pathology , Teratoma/pathology , Testicular Neoplasms/pathology , Testis/pathologyABSTRACT
Several months (an average of 12.86 months) after perineal needling of the cancerous prostate for the purpose of obtaining tissue for biopsy, a tumor nodule becomes clinically evident in the subcutaneous tissue of the perineum, at the site of the needling in 0.34% of the cases. This nodule presents the same histological picture as the biopsy of the prostatic tumor. This is a review of 15 such cases (12 collected from the literature and an additional three unpublished cases, two of which are personal observations). At the time of needling, no metastases could be clinically detected in any of the patients; the serum acid phosphatase was normal in 73% of them. The average age of the patients was 65.66 years. The perineal nodule was tender in 40% of the cases; its average size was 2.5 cm. Excision of the nodule was the most frequently employed form of management. At the time of reporting, 60% of the patients were living and well, for an average of 18.56 months after excision. In order to prevent perineal implantation, especially in patients who are at risk, it is suggested that a fine needle be employed to obtain prostatic tissue for biopsy, and that every possible therapeutic effort be made.
