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J Nippon Med Sch ; 85(1): 56-59, 2018.
Article in English | MEDLINE | ID: mdl-29540648

ABSTRACT

Purpura fulminans associated with antithrombin 3 (AT 3) deficiency is very rare in adults and neonates. It can be categorized into three principal forms - neonatal, idiopathic and acute infectious. Purpura fulminans has been reported to cause cardiac, pulmonary and renal damage in rare cases. We describe an adult case of purpura fulminans developing in association with AT 3 deficiency without infection following a surgical procedure, and acute kidney injury (AKI) developing secondary to rhabdomyolysis and disseminated intravascular coagulation (DIC). To the best of our knowledge there have been no previous cases of purpura fulminans and AKI developing in association with acquired AT 3 deficiency without infection after surgery.


Subject(s)
Acute Kidney Injury/etiology , Antithrombin III Deficiency/complications , Postoperative Complications/etiology , Purpura Fulminans/etiology , Acute Disease , Adult , Appendicitis/surgery , Digestive System Surgical Procedures , Disseminated Intravascular Coagulation/complications , Humans , Male , Rhabdomyolysis/etiology
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