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Prep Biochem Biotechnol ; 39(2): 201-7, 2009.
Article in English | MEDLINE | ID: mdl-19291582

ABSTRACT

A simple and solvent-free procedure to synthesize alpha,alpha'-bis(substituted benzylidene) cycloalkanones, catalyzed by copper(II) trifluoroacetate through crossed-aldol condensation of various aromatic aldehydes with cyclic ketones is reported. The reaction proceeded smoothly in good to excellent yields.


Subject(s)
Aldehydes/chemistry , Copper/chemistry , Ketones/chemistry , Ketones/chemical synthesis , Organometallic Compounds/chemistry , Trifluoroacetic Acid/chemistry , Catalysis , Molecular Structure , Stereoisomerism
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