ABSTRACT
Plants from the Aster species are known to be a rich source of bioactive chemical compositions and are popularly known for their medicinal properties. To investigate the relationship between the nine species of Aster, the floral fragrance and volatile profile patterns were characterized using E-nose and HS-SPME-GC-MS. Initial optimization for fragrance analysis was performed with Aster yomena using E-nose by evaluating the scent patterns in different flowering stages. Aster yomena exhibited varied scent patterns in each flowering stage, with the highest relative aroma intensity (RAI) in the full flowering stage. PCA analysis to compare and analyze the scent characteristics of nine Aster species, showed a species-specific classification. HS-SPME-GC-MS analysis of flowers from nine Aster species revealed 52 volatile compounds including ß-myrcene, α-phellandrene, D-limonene, trans-ß-ocimene, caryophyllene, and ß-cadinene. The terpenoid compounds accounted for the largest proportion. Among the nine Aster species flowers, Aster koraiensis had sesquiterpenes as the major component, and the remaining eight varieties had monoterpenes in abundance. These results could distinguish the species according to the scent patterns and volatile components of the nine Aster species. Additionally, flower extracts from the Aster species' plants exhibited radical scavenging antioxidant activity. Among them, it was confirmed that Aster pseudoglehnii, Aster maackii, and Aster arenarius had high antioxidant activity. In conclusion, the results of this study provide fundamental data of the volatile compound properties and antioxidant activity of Aster species, offering basic information of valuable natural sources that can be utilized in the pharmaceutical, perfume, and cosmetic industries.
ABSTRACT
BACKGROUND: Total knee arthroplasty (TKA) is widely accepted treatment for moderate or severe osteoarthritis and rheumatoid arthritis. Significant blood loss can be seen during the early postoperative period where a blood transfusion may be necessary. Closed suction drainage is known to prevent the formation of hematomas in the operative field, decrease tension on incisions, diminish delayed wound healing and reduce the risk of infection. Subcutaneous indwelling closed suction drainage method has been known to be beneficial and an alternative to the intraarticular indwelling method. This prospective randomized study was to compare the visible, hidden, total blood loss and postoperative hemodynamic change of subcutaneous and intraarticular indwelling closed suction drainage method after TKA. MATERIALS AND METHODS: One hundred and sixty patients with primary osteoarthritis who underwent unilateral TKA were enrolled; group A with subcutaneous (n = 78) and group B with intraarticular (n = 79) indwelling closed suction drainage method. Total blood loss, visible blood loss, internal blood loss, postoperative day 1, 5(th), 10(th) day hemoglobin, hematocrit levels were compared. Allogeneic blood transfusion rate and complications related to soft tissue hematoma formation were additionally compared. RESULTS: Allogenic transfusion requirements between subcutaneous drainage group and intraarticular drainage groups (6.4% vs. 24.1%) were significantly different (P = 0.002). Although the minor complications such as the incidence of bullae formation and the ecchymosis were higher in the subcutaneous indwelling group, the functional outcome at postoperative 2 year did not demonstrate the difference from intraarticular drainage group. CONCLUSION: Subcutaneous indwelling closed suction drainage method is a reasonable option after TKA for reduction of postoperative bleeding and transfusion rate.
ABSTRACT
PURPOSE: The purpose of this study was to determine the size of each meniscus and compare it with the contralateral limb using conventional knee magnetic resonance imaging (MRI) taken from previously uninjured, healthy, young volunteers. METHODS: The knee joints of 60 healthy volunteers (aged 21 to 43 years, 30 men and 30 women) were enrolled in this study. Standard 3.0-T MRI in a controlled setting was used. By use of the mid-coronal images, the height and width of each medial and lateral meniscus were measured. By use of the mid-sagittal images, the height and width of the anterior and posterior horns of each meniscus was measured. The whole length spanning from the most anterior margin to the most posterior margin of each meniscus was also measured. Mean, standard deviation, and 95% confidence interval values were determined for each measurement. RESULTS: There were 3 incomplete discoid lateral menisci (10%) in men and 2 incomplete discoid menisci (6.7%) in women. The study group with non-discoid knees comprised 27 men and 28 women. The power of this study ranged from 0.57 to 0.66. All values showed good reliability (intraclass correlation coefficient range, 0.887 to 0.974). There were no significant differences between right and left menisci (all P > .05). There were significant differences between genders. All parameters showed significant differences (P < .05) except the medial meniscus width (P = .221). CONCLUSIONS: In this small subset of patients, there were no differences between right and left meniscal measurements according to MRI. Therefore, when one is performing meniscal allograft transplantation, contralateral knee MRI may be useful to determine the required size. Identifying both the overall width and length of each meniscus is important when preparing an allograft. CLINICAL RELEVANCE: Contralateral knee MRI may be used for more accurate meniscal size measurement in patients undergoing meniscal allograft transplantation.
