1.
Bioorg Med Chem Lett
; 22(5): 2030-2, 2012 Mar 01.
Article
in English
| MEDLINE
| ID: mdl-22326167
ABSTRACT
The anomeric mixture of a series of O-galactolipid derivatives is revealed to be more toxic against several cancer cell lines than their either single component with the pure α- or ß-configuration. This interesting phenomenon has been confirmed on pairs of synthesized O-galactosyl anomers bearing length-varied alkyl chains at the lipid end. Furthermore, the most potent mixture was determined inoffensive to a normal cell line tested.