Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Bioorg Med Chem Lett ; 22(5): 2030-2, 2012 Mar 01.
Article in English | MEDLINE | ID: mdl-22326167

ABSTRACT

The anomeric mixture of a series of O-galactolipid derivatives is revealed to be more toxic against several cancer cell lines than their either single component with the pure α- or ß-configuration. This interesting phenomenon has been confirmed on pairs of synthesized O-galactosyl anomers bearing length-varied alkyl chains at the lipid end. Furthermore, the most potent mixture was determined inoffensive to a normal cell line tested.


Subject(s)
Antineoplastic Agents/chemistry , Antineoplastic Agents/pharmacology , Galactolipids/chemistry , Galactolipids/pharmacology , Cell Line, Tumor , Cell Survival/drug effects , Drug Synergism , Humans , Neoplasms/drug therapy
SELECTION OF CITATIONS
SEARCH DETAIL
...