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1.
Neurol India ; 70(2): 660-663, 2022.
Article in English | MEDLINE | ID: mdl-35532635

ABSTRACT

Background: Electrophysiological investigations are now very common in clinical investigations. Event-related potential (ERP) is also common in most electrophysiological recording in which P300 is considered as the best indicator of psychological status. P300wave latency and amplitude are the best indicators of superior mental function status. Variability in P300 has been demonstrated in diseases exhibiting cognitive abnormalities. Objective: The present study aimed to generate the normative data of P300 wave latency and amplitude in healthy young adults of 18-25 years age group in healthy young adults. Material and Methods: Hundred healthy young adults age (18-25 years) were analyzed for P300 using auditory oddball paradigm [Octopus NCV/EMG/EP-4 Channel Machine (Model name- CMEMG 01)], after taking anthropometric measurements (height, weight, and BMI). Whole data were collected after taking the willing consent of participants recruited for the study, and approval of Institute's ethics committee was taken before the start of study. Normally, distributive data were presented in the form of mean, standard deviation, and Pearson correlation was used to see check the correlation using MS-excel 2007. Results: The mean P300 latency and amplitude were 281.38 ± 33.39 ms and 4.53 ± 1.67µV, respectively, in healthy young adults with mean age 19.81 ± 1.80 years. With age the P300 latency was significantly positively correlated. Conclusions: This study results reflected normative data of P300wave latency and amplitude in healthy young adults of 18-25 years age group.


Subject(s)
Event-Related Potentials, P300 , Evoked Potentials, Auditory , Adolescent , Adult , Electroencephalography , Event-Related Potentials, P300/physiology , Evoked Potentials/physiology , Evoked Potentials, Auditory/physiology , Humans , Young Adult
2.
J Basic Microbiol ; 54(8): 843-50, 2014 Aug.
Article in English | MEDLINE | ID: mdl-23828308

ABSTRACT

An extremely halotolerant bacterium designated as HPSSN35C was isolated from saline soil of Dwarka beach, India. It exhibited growth over a wide range of NaCl in medium varying from 0 to 6 M. The isolate produced peach-pink pigment above ∼1.3 M NaCl. The culture was characterized using biochemical tests, bioMerieux Staph identification kit, API ID32 Staph system, and Biolog. Due to slow growth and extreme salt tolerance no ID was obtained in Biolog. Antibiotic sensitivity to various antibiotics was tested. Phenotypic characterization showed that it belonged to the novobiocin resistant staphylococci group. Analysis of 16S rRNA gene sequence comparison of 1452 base pairs showed that isolate is closely related to Staphylococcus saprophyticus group with close relationship to Staphylococcus arlettae (99% similarity). The halotolerant S. arlettae described in literature till date have been reported to tolerate 4.5 M NaCl and produce white to yellow pigment. The present study reports for the first time extremely halotolerant S. arlettae exhibiting growth up to ∼6 M NaCl and producing peach-pink pigment above ∼1.3 M NaCl.


Subject(s)
Salt Tolerance/genetics , Soil Microbiology , Staphylococcus/growth & development , Bacterial Typing Techniques , Base Sequence , Drug Resistance, Bacterial , India , Microbial Sensitivity Tests , Molecular Sequence Data , Novobiocin/pharmacology , Phylogeny , Pigments, Biological/biosynthesis , RNA, Ribosomal, 16S/genetics , Salinity , Sequence Analysis, DNA , Sodium Chloride/metabolism , Soil/chemistry , Staphylococcus/drug effects , Staphylococcus/genetics , Staphylococcus/isolation & purification
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