Subject(s)
Myotonic Dystrophy/diagnosis , Adult , Electromyography , Hand Strength , Humans , Male , Neurologic ExaminationABSTRACT
OBJECTIVE: To know the clinical profile, presence of various risk factors for stroke at moderate altitude and to study its relationship with hypertension and polycythemia at moderate altitude. METHODS: We analyzed the data of 100 patients, consecutively admitted to a hospital situated at an moderate altitude of 2200 meters MSL of Sub-Himalayan ranges and studied the age, gender, geographical distribution, clinical features and presence of various risk factors in relation to stroke. This is not only the first study conducted in Himachal Pradesh but also first study in India to be conducted at moderate altitude (2000-3000 meters MSL). RESULTS: Males outnumbered females (66% males, 34% females) with rural predominance (73% rural, 27% urban). Cerebral infarction (69%) was more common but primary intracerebral haemorrhage (26%) was more common than found in the West. Hypertension (62%) and smoking (60%) were most common risk factors present and polycythemia was not a significant risk factor at this altitude. CONCLUSION: Incidence of stroke was found to be lower than the study conducted at low altitude. incidence of various types of stroke was similar to other Indian studies. The combination of opposite effects of decreased hypertension and increased haematocrit could not be demonstrated at this altitude and smoking was more common than in other studies and other risk factors prevalent were same as that for low altitude.
Subject(s)
Altitude , Stroke/epidemiology , Adult , Aged , Aged, 80 and over , Cerebral Infarction/epidemiology , Female , Humans , Hypertension/complications , Hypertension/epidemiology , Incidence , India/epidemiology , Male , Middle Aged , Polycythemia/complications , Polycythemia/epidemiology , Reference Values , Risk Factors , Smoking/adverse effects , Smoking/epidemiology , Stroke/diagnosis , Stroke/etiologyABSTRACT
Cysticercosis consists of infection with the small bladder-like larvae of the pork tapeworm Taenia solium. The life cycle of parasite is maintained between man and pig infected with cysticerci. Epilepsy is the most common presentation of neurocysticercosis; focal signs, headache, involuntary movements and global mental deterioration are other symptoms. Psychosis is a rare presentation and may be seen in up to 5% of patients. We present a 25 years old male, who had been under treatment from psychiatry OPD for psychosis for one year, developed generalized tonic-clonic seizures. CT scan of brain revealed multiple calcified and hypodense lesions with surrounding oedema. Histopathological examination of subcutaneous nodule confirmed the diagnosis of neurocysticercosis.
Subject(s)
Cysticercus/isolation & purification , Neurocysticercosis/diagnosis , Psychotic Disorders/diagnosis , Adult , Animals , Antipsychotic Agents/therapeutic use , Diagnosis, Differential , Follow-Up Studies , Humans , India , Male , Psychotic Disorders/drug therapy , Risk Assessment , Severity of Illness Index , Tomography, X-Ray Computed/methodsABSTRACT
We present a 55 years old male with severe anemia with history of pain abdomen for 2 weeks and malena of 10 days duration. He was taking NSAID (Diclofenac sodium). Upper GI endoscopy done twice did not reveal any abnormality. Upper gastrointestinal (UGI) barium series with small bowel follow through revealed a diverticulum on medial wall of second part of duodenum and there was evidence of ulcer in diverticulum. He underwent diverticulectomy. On follow up after 6 months patient was asymptomatic.
Subject(s)
Diclofenac/adverse effects , Diverticulum/chemically induced , Duodenal Diseases/chemically induced , Gastrointestinal Hemorrhage/chemically induced , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Fluoroscopy , Humans , Low Back Pain/drug therapy , Male , Middle AgedABSTRACT
A random, observer blind, crossover design of study was undertaken in twelve normal male volunteers. Both propranolol (40 mg) and atenolol (50 mg) in single dose oral administration had significantly reduced the heart rate, systolic blood pressure and the value for double product under resting and postexercise conditions compared to the corresponding pretreatment values. Orally administered activated charcoal (15 g) had abolished the haemodynamic effects of propranolol but failed to do so against atenolol under both resting and postexercise periods. The results suggest the possibility of successful antidotal intervention with activated charcoal in the case of propranolol overdosage only.
