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1.
Clin Exp Optom ; 96(3): 349-51, 2013 May.
Article in English | MEDLINE | ID: mdl-22970978

ABSTRACT

Primary extramedullary plasmacytomas of the eyelid are rare with only five other cases reported in the literature. A 43-year-old Chinese man presented with painless swelling of the left lower eyelid that developed over the past two years. An incisional biopsy and histopathological analysis of the lesion revealed a primary extramedullary plasmacytoma of the eyelid. The tumour was completely excised. There has been no tumour recurrence over the last five years. This tumour should be among those considered when encountering an atypical adnexal lesion. A systemic examination, relevant clinical investigations, as well as life-long monitoring are essential for these patients due to the strong association of extramedullary plasmacytoma with multiple myeloma. When a lesion can be completely resected, surgery provides similar results to radiotherapy.


Subject(s)
Eyelid Neoplasms/surgery , Plasmacytoma/surgery , Adult , Eyelid Neoplasms/pathology , Humans , Male , Plasmacytoma/pathology
3.
Graefes Arch Clin Exp Ophthalmol ; 249(12): 1755-60, 2011 Dec.
Article in English | MEDLINE | ID: mdl-20607549

ABSTRACT

PURPOSE: To describe the epidemiology of ocular injuries presenting to the University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia. DESIGN: Prospective analysis of all ocular trauma injuries presenting to the Department of Ophthalmology in UMMC from 1 January 2008 to 31 December 2008. PARTICIPANTS: A total of 603 eyes of 546 patients were recruited for the study. METHODS: All patients presenting to the department with ocular trauma injuries were assessed by an ophthalmologist. Data on the type and source of injury, demographic profile of the patients, and clinical presentation were documented using a uniform and validated datasheet. RESULTS: Among eye injury cases, 481 patients (88.1%) were male, with a male-to-female ratio of 7.4:1. Of the patients, 412 (75.5%) were Malaysian while the remaining 134 (24.5%) were of non-Malaysian nationality. The average age was 31.5 years (range 1-81 years). A total of 238 injured eyes (43.6%) were work-related. The common sources of eye trauma include the use of high-powered tools (30.8%), motor vehicle accident (23.1%), and domestic accidents (17.7%). Only six patients (2.5%) reported to having used eye protective device (EPD) at time of their work-related injuries. CONCLUSIONS: A major cause of preventable ocular injuries in Malaysia was work-related trauma. Ocular injuries can be reduced by the use of eye protection devices and the implementation of appropriate preventive strategies to address each risk factor. Effective training is an integral part of occupational safety and health, which should be made mandatory at the workplace. In addition, there should be a continual assessment of safety and health issues at the workplace. A long-term database of all ocular injuries in Malaysia is recommended, to aid research on a larger scale and the development of new preventive strategies for ocular injuries.


Subject(s)
Eye Injuries/epidemiology , Population Surveillance , Academic Medical Centers/statistics & numerical data , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Humans , Infant , Malaysia/epidemiology , Male , Middle Aged , Prospective Studies , Young Adult
4.
International Eye Science ; (12): 627-629, 2010.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-641840

ABSTRACT

Sarcoidosis is a rare and potentially disabling disease in the paediatric age group. Clinical management of such cases is difficult and requires long-term monitoring. We report a case of a 9 years old Caucasian girl who presented initially with bilateral chronic anterior uveitis, cataracts and glaucoma secondary to sarcoidosis. She was treated with Guttae Levobunolol, topical and systemic steroids over the last 2 years but subsequently required cataract extractions with foldable intraocular lens uveitis was well controlled with both topical steroids and low dose methotrexate over the last 2 months following cataract surgery. Her full blood counts and renal functions are monitored regularly. There was no adverse effect from the methotrexate reported so far. Sarcoidosis is a multisystem disease and requires multi-disciplinary input from ophthalmologists, neurologists and paediatricians. Medical and surgical treatment of such ocular manifestations is challenging. This case highlights both the safety of low dose methotrexate in the management of childhood chronic uveitis and the need for prompt treatment in such cases to avert significant morbidity from this disease.

5.
Cornea ; 27(10): 1186-8, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19034139

ABSTRACT

Primary corneal myxoma is extremely rare. It has only been reported on 2 previous occasions. Secondary corneal myxomas are more common, arising from corneal diseases such as infective keratitis, keratoconus, and bullous keratopathy. Myxomas occur commonly in other soft tissues such as the heart, paranasal sinuses, and muscles but can rarely present in periocular structures including the conjunctiva, orbit, and eyelid. Ours is only the third case of primary corneal myxoma reported in the literature and illustrates several unusual features. These include an inferonasal location between the corneal epithelium and Bowman layer and with no relationship to the corneal stroma, rapid tumor growth over a 3-month period, and no previous ocular trauma or conjunctival pathology. The histology of this lesion has an important part to play in the management of this condition as it determines the cellular origin, establishes a benign or malignant state, and helps with treatment and prognosis. One reported case of primary corneal myxoma recurred within 2 months after local resection. This was treated with bandage soft contact lens, and no recurrence had been reported since. Our case is now 12 months post op and has had no recurrence.


Subject(s)
Corneal Diseases/pathology , Corneal Diseases/surgery , Eye Neoplasms/pathology , Eye Neoplasms/surgery , Myxoma/pathology , Myxoma/surgery , Aged , Corneal Diseases/diagnostic imaging , Eye Neoplasms/diagnostic imaging , Humans , Male , Microscopy, Acoustic , Treatment Outcome
6.
J Cataract Refract Surg ; 33(8): 1426-8, 2007 Aug.
Article in English | MEDLINE | ID: mdl-17662436

ABSTRACT

PURPOSE: To evaluate changes occurring in central corneal thickness (CCT) immediately after uneventful cataract surgery. METHODS: Thirteen consecutive patients who had uneventful phacoemulsification surgery by the same experienced surgeon were prospectively evaluated for CCT measurements 1 hour preoperatively and 1 hour, 1 day, and 1 week postoperatively. The unoperated eye also had CCT measurements simultaneously on all occasions and served as a control. All patients provided informed consent. SETTING: Department of Ophthalmology, Royal Glamorgan Hospital, Llantrisant, UK RESULTS: Mean age of the patients was 69 years. Central corneal thickness was 550.34 microm preoperatively, 626.39 microm at 1 hour, 585.80 microm at 1 day, and 553.80 microm at 1 week. In the control group, CCT remained stable, within +/-2 microm of preoperative readings. CONCLUSIONS: Central corneal thickness increased by approximately 13.81% in the immediate postoperative period (at 1 hour). It remained increased by 6.44% on day 1 compared with preoperative values and gradually reduced to preoperative levels by the 1-week postoperative period (0.57% difference). Intraocular pressure (IOP) measured postoperatively in the first week may be falsely elevated to some extent because of the increased corneal thickness in the immediate postoperative period; thus, not all IOP rises have be treated in this period in healthy uncompromised eyes.


Subject(s)
Cornea/pathology , Corneal Diseases/etiology , Lens Implantation, Intraocular , Phacoemulsification , Postoperative Complications , Aged , Aged, 80 and over , Diagnostic Techniques, Ophthalmological , Female , Humans , Intraocular Pressure/physiology , Male , Middle Aged , Prospective Studies
8.
J AAPOS ; 10(6): 585-6, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17189158

ABSTRACT

Dermatitis artifacta is a factitious dermatological disorder with many forms of presentation in any part of the body. It is commonly documented in dermatological cases but rarely presented as an ophthalmic condition. The diagnosis of dermatitis artifacta is often concluded after rigorous and repeated investigation. Histological sampling of skin lesions is usually required in these cases to exclude masquerading skin lesions such as basal cell carcinoma, vasculitis, or herpetic skin lesions.


Subject(s)
Dermatitis/psychology , Factitious Disorders/psychology , Self Mutilation/psychology , Skin/injuries , Child , Dermatitis/diagnosis , Diagnosis, Differential , Face , Factitious Disorders/diagnosis , Female , Humans , Orbit , Self Mutilation/diagnosis
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