Subject(s)
Abnormalities, Multiple/genetics , Chromosomes, Human, Pair 14/genetics , Prader-Willi Syndrome/genetics , Child , Female , Genetic Markers/genetics , Humans , Infant , Intellectual Disability/genetics , Karyotyping , Male , Phenotype , Prader-Willi Syndrome/diagnosis , Translocation, GeneticABSTRACT
The results are described of a retrospective study, per questionnaire among parents who adopted children from developing countries. Results are given of 228 children. Approximately 100 gastro-intestinal, 80 upper respiratory (nose-, ear- and throat-)diseases and 50 dermatologic problems were diagnosed. We further studied the state of nutrition and the medical information which the parents received from the country of origin. 30-40% of the children arrived malnourished and the catch-up growth was determined after a stay of at least 6 months in the Netherlands. Suggestions are made for a general medical examination of adopted children from the developing countries.
Subject(s)
Adoption , Child Nutritional Physiological Phenomena , Ethnicity , Health Surveys , Child , Child, Preschool , Developing Countries , Female , Growth , Health Status , Humans , Infant , Male , Morbidity , NetherlandsABSTRACT
The variability and predictability of the plasma concentration of ampicillin and kanamycin in new-born infants being treated for infections are discussed. For kanamycin a standard dose regimen of 7.5 mg/kg/12h is recommended.
Subject(s)
Ampicillin/blood , Infant, Newborn , Kanamycin/blood , Age Factors , Humans , Kinetics , Time FactorsABSTRACT
Ampicillin blood levels after i.m. injection were analysed according to a one and a two-compartment pharmacokinetic model. The two-compartment model gave no substantially better fit to the data than a one-compartment model. To fit the one-compartment model two computer programs based on different numerical methods, were tested. The BMD program gave satisfactory results in all cases.
